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46 Cards in this Set
- Front
- Back
Major Depressive Episode
5 or more of the following sx during the same 2 week period and represents a change from previous functioning. At least one of the sx must be (1) depressed mood or (2) loss of interest or pleasure. |
1. Depressed mood most of the day, nearly every day (can be irritable in kids and teens)
2. Markedly diminished interest in all, or almost all, activities 3. Significant weight loss/gain or decrease/increase in appetite 4. Insomnia or hypersomnia 5. Psychomotor agitation or retardation (observable by others, not just subjectively) 6. Fatigue or loss of energy 7. Feelings of worthlessness or excessive guilt 8. Poor concentration or inability to make decisions 9. Recurrent thoughts of death, recurrent SI with or without specific plan |
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MDD-Symptoms
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MDD and Mental Status Exam
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MDD: Workup
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Pediatric MDD Presentation
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Kids-may present as lack of wt gain, GI upset, headaches, irritability, malaise, aggression
Teens-may present as irritability, severe misconduct, poor grades, “wrong crowd” 60% have first degree relative with MDD |
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MDD in elderly
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Agitation and somatic concerns common
“Pseudodementia Don’t neglect psychotherapy Don’t undertreat |
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General medical conditions that may biologically cause MDD
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General medical conditions that can cause MDD
• Autoimmune (SLE) • Endocrine (hypothyroid, DM, adrenal) • Postviral infections (influenza, HIV, mono) • Toxicity (lead, mercury) • CNS (Parkinson’s, CVA, Alzheimer’s) • CA • Metabolic (B12 deficiency) |
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MDD 3 Tx Phases & Goal
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MDD: 3 treatment phases:
1. Acute 2. Continuation (6-12mos) 3. Maintenance Goal is full restoration of functioning and prevention of relapse/recurrence |
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MDD: Psychiatry Referral
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MDD: Psychiatry Referral
• Patient or family request • Uncertain diagnosis • Suicidal • Psychotic features • Substance abuse • Other psychiatry comorbidities • Needs ECT • Failure of 2 reasonable med trials |
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SAD: Treatment
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SAD: Treatment
• Mild sx: spend time outdoors, sunlight • Phototherapy o Suppresses brain’s secretion of melatonin o 10,000 lux for 30 minutes in am o Need prescription; Insurance coverage • May use antidepressant |
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Dysthymia
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Dysthymia:
o Extremely chronic, yet milder depression o Usually “double depression” o Can be very negative, sarcastic, never happy o Marriage/friendships not rewarding o Same sx as MDD, but don’t meet full criteria o 40% of those with MDD meet criteria o Sx → clinically sign distress/impairment |
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DYSTHYMIA: Depressed mood for most of the day, for more days than not, for at least 2 years. In kids & teens, mood can be irritable and must be at least 1 year.
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While depressed, 2 or more of the following:
1. Poor appetite or overeating 2. Insomnia or hypersomnia 3. Low energy, fatigue 4. Low self esteem 5. Poor concentration, difficulty making decisions 6. Hopelessness |
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Postpartum Depression
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Postpartum Depression
o Within 4 weeks postpartum o Postpartum “blues” may or may not precede it (<2 wks; 60%) o Sx are identical to MDD o Feel inadequate to care for baby o Most recover in a few months to a year |
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Adjustment Disorders
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Postpartum Depression
o Within 4 weeks postpartum o Postpartum “blues” may or may not precede it (<2 wks; 60%) o Sx are identical to MDD o Feel inadequate to care for baby o Most recover in a few months to a year |
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Adjustment Disorders
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Adjustment Disorders
o Clinically significant emotional or behavioral symptoms that develop in response to a stressor o Reaction is disproportionate to the nature of the stressor or functioning is sign impaired o Symptoms must occur within 3 months o |
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Adjustment Disorders: Treatment
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Adjustment Disorders: Treatment
o Depends on symptom severity o Usually supportive o Medication not normally needed o Possibly short term psychotherapy o Encourage exercise, relaxation training, socialization, support groups |
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Depressive Disorder, NOS
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Depressive Disorder, NOS
Depressive symptoms not meeting criteria for any specific depressive disorder |
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Bipolar Spectrum Mood Disorders
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Bipolar Spectrum Mood Disorders
o “Manic depression” o Usually present depressed o Caution with antidepressants o High risk of suicide, esp when depressed |
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Bipolar Disorder
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Bipolar Disorder
o 1-2% of U.S. population o Late teens-early 20s o Family history important o Failure/worsening with antidepressants o Possible seasonal changes |
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Manic episode: DSM-IV
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Manic episode: DSM-IV
Distinct period of abnormally and persistently elevated or irritable mood, lasting at least 1 week (or any duration if hospitalization necessary). |
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Manic Episode
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Besides mood disturbance, > 3 of the following:
– Inflated self esteem or grandiosity – Decreased need for sleep – More talkative than usual; pressure to keep talking – Flight of ideas; racing thoughts – Distractibility – ↑ goal directed activity or psychomotor agitation – Excessive involvement in activities that are high risk |
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Manic Episode
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Manic Episode
o Mood disturbance is sufficiently severe to cause marked impairment, to necessitate hosp to prevent harm to self or others, or psychotic features o Manic-like episodes that are clearly caused by antidepressant treatment (meds, ECT, light therapy) should not count toward dx of bipolar disorder |
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Hypomanic Episode
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Hypomanic Episode
o Distinct period of persistently elevated or irritable mood lasting > 4 days that is clearly different form the usual mood o Need 3 or more of same 7 sx of mania o Episode associated with an unequivocal change in functioning that is uncharacteristic of the person o Disturb in mood and change in funct is observable by others o Episode is not severe enough to cause marked impairment, to necessitate hospitalization, and no psychotic features |
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Cyclothymia
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Cyclothymia
o For at least two years, the presence of numerous periods with hypomanic sx and numerous periods with depressive sx that do not meet criteria for a MDE o During the two year period, the person cannot be without sx for more than 2 mos |
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Anxiety Disorder Prevalence
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Anxiety Disorders
o Up to 25% lifetime prevalence rate o Most common ages 20-45 o Female > Male o Start earlier in childhood/adolescence o 1 in 7-8 kids/teens |
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Anxiety Disorders
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Anxiety Disorders
o Frequent visits to primary care provider o Majority are untreated (unrecognized as anxiety) o Often is a comorbid mood disorder: anxious depression o ETOH 2-4x more common with anxiety dx |
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Hallmarks of Anxiety Disorders
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HALLMARKS OF ANXIETY DISORDERS
o Physiological Arousal o Sweating, flushing, shortness of breath, GI upset/diarrhea, palpitations/chest pain, insomnia, shaking, dizziness o Subjective Apprehension (aware of feeling nervous) o Worry, tension, inability to concentrate, restlessness, feelings of fear/dread |
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Anxiety Disorder Etiology
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Anxiety disorder etiology
Genetic Biologic o ANS: excessive response to moderate stimuli o GABA, Serotonin, and Norepinephrine GABA & serotonin are calming agents Psychosocial: Modeling from parents Learned: Conditioned response, parents |
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Anxiety Disorder: 1st Must R/O -
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Anxiety Disorder: 1st Must R/O
• Hyperthyroidism • Hypoglycemia • COPD • Hyperparathyroidism • Cardiac arrhythmias |
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Drugs that Can Induce Anxiety
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Drugs that can induce anxiety:
B-adrenergic agonists Steroids Thyroid hormone, etc Caffeine Amphetamines Cocaine Withdrawal from alcohol or sedatives |
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Panic Disorder
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Panic Disorder
• 2-3x higher in females • Usually begins early adulthood • Major life transitions can precipitate • 4-8x increased risk in first degree relative • Chronic, relapsing nature • Recurrent panic attacks (5-30min) • Panic” vs. panic attack • Usually no trigger • May avoid normal activities • Attacks may occur daily or rarely |
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Panic Disorder Hallmark
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Panic Disorder Hallmark:
Worry about future panic attacks |
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PANIC ATTACK - Intense fear or discomfort in which 4 or more of 13 sx abruptly appear and reach peak within ten minutes
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1. Fear of losing control
2. Palpitations, tachycardia 3. Trembling, shaking 4. Shortness of breath 5. Feeling of choking 6. Chest pain or discomfort 7. Nausea or GI distress 8. Feeling dizzy, lightheaded 9. Derealization or depersonalization 10. Sweating 11. Chills/hot flushes 12. Paresthesias 13. Fear of dying |
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Agoraphobia
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Agoraphobia
o At least one of the attacks has been followed by > 1 month > 1 of the following: 1. Persistent concern about having another attack 2. Worry about implications of the attack or its consequences (e.g., losing control, having an MI, “going crazy”) o Signif change in behavior related to the attacks |
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Panic Disorder: DSM-IV
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Panic Disorder: DSM-IV
o Recurrent unexpected panic attacks o > 1 of the attacks has been followed by > 1 of these: 1. Persistent concern about having another attack 2. Worry about the implications of the attack or its consequences (e.g., losing control, having an MI, “going crazy”) o Significant change in behavior related to the attacks |
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Post Traumatic Stress Disorder
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Post Traumatic Stress Disorder
Males-combat exposure Females-sexual abuse, assault Acute-sx <3 months Chronic-sx >3months Delayed onset-sx manifest after 6months Intense guilt, feeling “dead inside” common |
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PTSD: DSM-IV: Exposure to a traumatic event where both of the following are present -
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PTSD: DSM-IV: Exposure to traumatic event where –
1. The person experienced, witnessed, or was confronted with an event that involved actual or threatened death or serious injury 2. The response involves a sense of helplessness or fear (in kids, may manifest as disorganized or agitated behavior) |
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PTSD: DSM-IV:
Three symptom clusters: |
PTSD: DSM-IV: 3 symptom clusters:
1) Reexperiencing the trauma 2) Avoidance of stimuli 3) Hyperarousal |
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PTSD: DSM-IV
Traumatic event is “relived” by experiencing at least one: |
1. Intrusively distressing recollections of event (in kids, may be repetitive play that involves specific aspects of the trauma)
2. Recurrent distressing dreams about the event 3. Sense that the event is recurring via “flashback” episodes 4. Intense psychological distress in response to cues that recall the event 5. Physiological sx cued by remembering the event |
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PTSD: DSM-IV: Persistent avoidance of stimuli associated with the trauma and “numbing” of general responsiveness.
At least three of the following: |
1. Avoidance of thoughts, feelings, or conversations associated with the event
2. Avoidance of activities, places, or people that arouse memories of the event 3. Inability to recall an important aspect of event 4. Diminished interest in previously enjoyed activities 5. Feeling of detachment from others 6. Blunted affect (e.g., unable to have emo bonding) 7. Negative view of future |
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PTSD: DSM-IV, cont: Persistent symptoms of hyperarousal as indicated by at least 2 of the following:
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1. Insomnia
2. Explosive behavior 3. Difficulty concentrating 4. Hypervigilance 5. Exaggerated startle response • Symptoms have persisted for > 1month • Symptoms result in clinically significant impairment in social or occupational functioning |
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GAD
Generalized Anxiety Disorder: Anxiety associated with > 3 of the following: (only 1 required for kids) |
– Restlessness, keyed up, on edge
– Easily fatigued – Difficulty concentrating or mind going blank – Irritability – Muscle tension – Insomnia Anxiety or physical sx cause clinically signif distress or impairment in social, work, or other functioning |
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Social Anxiety: DSM-IV
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• Marked and persistent fear of > 1 social or performance situation where the person is exposed to unfamiliar people or to possible scrutiny by others.
• Fears that he/she will act in a way (or show anxiety sx) that will be humiliating. (In kids, anxiety must occur with peers, not just with adults) • Exposure to feared situation almost always provokes anxiety, which may present as panic attack. • Person recognizes fear as unreasonable |
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Social Anxiety: DSM-IV
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Social Anxiety: DSM-IV
• Feared situation is avoided or else endured with intense anxiety • Avoidance, anxious anticipation, or distress interferes significantly with the person’s normal routine, occupational functioning, or social activities/relationships • If under age 18, duration is at least 6 mos |
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Social Anxiety
Premorbid Risk Factors |
Social Anxiety Premorbid Risk Factors:
Childhood shyness Overprotective or rejecting parents Exposure to domestic violence Death in family Early parent/child separation Other childhood trauma |
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Anxiety Disorder, NOS
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Anxiety Disorder, NOS
Anxiety symptoms that don’t meet criteria for any specific anxiety disorder |