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102 Cards in this Set
- Front
- Back
what is the forebrain divided into?
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telencephalon and diencephalon
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what is the other name for the midbrain?
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mesencephalon
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what is the other name for the hindbrain? what is it divided into?
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rhombencephalon; metencephalon and myelincephalon
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what does the telencephalon form?
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grey (cortex) and basal ganglia
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what does the diencephalon form?
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thalamas and hypothalamus
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what does the mesencephalon form?
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superior and inferior colliculus
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what does the metencephalon form?
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pons and cerebellum
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what does the myelincephalon form?
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medulla and spinal cord
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what is the striatum made of?
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caudate and putamen
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what is the lenticulate nucleus made of?
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the putamen and globus pallidus
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what fibers travel from the cortex to the striatum?
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cortical striate fibers
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the remnant of what sulcus separates the dorsal and ventral thalamus?
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sulcus limitans
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what does the dorsal part of the thalamus deal with? ventral?
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dorsal: sensory
ventral: motor, autonomic impulses (heart rate, respiration, etc) |
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what part of the thalamus receives the optic tract and auditory impulses respectively?
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lateral and medial geniculate
lat: optic med: auditory |
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what structures are included in the limbic lobe?
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amygdala, hippocampus, cingulate gyrus, hippocampal gyrus
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what is another name for the central sulcus?
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rolandic fissure
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what area is the precentral gyrus? what does it give rise to?
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area 4, gives rise for the most part to the corticospinal tract
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what are the 3 subdivisions of the inferior frontal gyrus?
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par orbitalis, pars triangularis, and pars opercularis
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where are areas 44 and 45? what are they collectively called?
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in front of the base of the precentral gyrus, called Broca's speech area
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what is Broca's area responsible for? what happens if a lesion is here?
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production of speech; muscles of the larynx/pharnyx will lose their motor associations (they will not be paralyzed)
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what are the area numbers of the postcentral gyrus? what are the area numbers of the rest of the parietal lobe?
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from anterior to posterior: 3, 1, 2
rest of the parietal lobe: 5 and 7 (sensory association cortex) |
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what is hemineglect? what can it result from?
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results from a lesion in area 5 or 7; people don't recognize the opposite side of their body as belonging to themselves
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where are areas 41 and 42? what are they responsible for?
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anterior and posterior temporal gyri; auditory impulses come into consciousness here
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where is area 22? what is it responsible for?
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superior and middle temporal gyri; is the auditory association cortex
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what is receptive aphasia? what does it result from?
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pt can't understand what is being spoken; results from a lesion in area 22
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what is expressive aphasia? what does it result from?
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loss of ability to speak; results from a lesion in Broca's area
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where is Wenicke's area? what does a lesion here result in?
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inferior to the posterior part of the lateral fissure; lesion results in loss of language all together
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where does vision come to a conscious level?
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area 17 (primary visual cortex), which is on either side of the calcarine fissure
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where is the visual association cortex located? what does this allow for?
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areas 18 and 19 (lateral from area 17); allows us to know what we see
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what occurs if a lesion is present in area 18? 19?
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18: cortical blindness (person can see, but doesn't understand what is seen)
19: person will know what to do with an object, but won't be able to name the object |
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what kind of disease is Alz?
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disease of the association cortex
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what gyrus is important in the ability to lay down new memories?
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cingulate
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what represents the closure of the anterior neuropore from embryological development?
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lamina terminalis
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what does the posterior commissure connect?
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2 areas on either side of the superior colliculus called the pretectal nuclei (concerned with visual reflexes)
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what relays impulses from the hypothalamus to the brainstem?
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dorsal longitudinal fasciculus
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what is the subcallosal gyrus important in?
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receiving olfactory sensations
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where is the paraolfactory area of Broca? what does it do?
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anterior to the lamina terminalis; receives olfactory sensations
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where does the fornix terminate?
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in the mamillary bodies
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what is contained in the uncus?
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amygdala
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what can a massive internal bleed cause?
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uncal herniation due to pressure on the tentorium cerebelli
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what is another name for the insular cortex?
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isle of reile
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what is the difference between the insular cortex and the parietal lobe?
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insular: visceral association center
parietal: somatic sensory cortex |
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what provides dopamine to the cerebral cortex? what would a lack of this structure be seen in?
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substantia nigra, Parkinson's disease
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what are the only sensations from the body that do not pass through the posterior limb of the internal capsule on their way to the primary cortex?
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olfaction, vision, and auditory
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what is the subicular?
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transition between a 6-layered cortex and a 3-layered cortex
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what structure does the subicular transition into, which then interdigitates with the dentate gyrus?
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the cornuu ammonis (Ammon's horn)
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what structure of the fornix are important in memory and emotions?
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fimbra
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what is Papez's circuit?
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HF --> fornix --> mammillary bodies --> mammilothalamic tract --> anterior nucleus of dorsal thalamus --> anterior limb of internal capsule --> cingulate gyrus --> cingulum --> hippocampal gyrus --> HF
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what structures make up the limbic lobe?
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amygdala, hippocampus, cingulate gyrus, olfactory impulses
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what kind of neurons are the olfactory neurons?
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bipolar sensory neurons
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what is the name of the cells that olfactory neurons synapse on?
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mitral cells
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what 5 things is the medial olfactory tract made of?
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septum pellucidum
olfactory trigone medial portion of the anterior perforated substance subcallosal gyrus paraolfactory area of Broca |
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neurons from the medial olfactory tract send their axons to the hypothalamus via what bundle? where does this bundle terminate?
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medial forebrain bundle; terminates on the ventromedial hypothalamic nucleus
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what is the pathway of the lateral olfactory tract?
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prepiriform cortex --> anterior perforated substance --> corticomedial amygdaloid nucleus --> basolateral nucleus --> hippocampal gyrus --> HF
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what kind of impulses can stimulate Papez's circuit?
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olfactory
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what is the last part of the cortical areas to become myelinated in man?
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the prefrontal cortex
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what 2 things can result from lesions in the amygdala?
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placidity or sham rage
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what is dr. kinney's favorite disease that can affect the limbic structures?
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paraneoplastic limbic encephalitis
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what disease often affects chronic alcoholics and impairs their ability to lay down new memories? what area of the brain does this affect?
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Wernicke-Korsakoff psychosis; affects the mammillary bodies
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what is akinetic mutism?
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loatheness to move, depression, decreased memory
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what transmits impulses from the mammillary bodies to the anterior nucleus of the thalamus?
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mammalothalamic tract
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what is the result of bilateral paralysis of the abducens nuclei?
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eyes turn medially, bilateral internal strabismus, diplopia
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what does paralysis of conjugate gaze mean?
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patient cannot move their eyes in the horizontal plane
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what nutrient deficiency accompanies chronic alcohol consumption?
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thiamine
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what is thiamine required for?
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trans-ketolase activity, especially in the hexose-monophosphate shunt
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what part of the brain degenerates in chronic alcoholics?
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anterior vermis of the cerebellum
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what is confabulation?
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when the patient makes up logical stories to fill in gaps in their memory
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what is kluver-bucy syndrome?
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when herpes simplex attacks the medial temporal lobes, particularly the amygdala and the hippocampus
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what is psychic blindness?
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patients don't understand what they see and they examine everything orally
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depression is linked to lesions where?
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in the left frontal lobe
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mania is linked to lesions where?
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in the right frontal lobe
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what kind of abnormal brain anatomy is associated with schizophrenia?
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decreased superior temporal gyrus volume compared to controls, enlarged ventricles, decreased blood flow to the frontal cortex
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what parts of the brain does Pick's disease affect? what parts does it never affect?
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affects the frontal and/or temporal lobe, but NEVER the parietal and occipital lobes
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how to Pick's patients present?
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with behavioral problems first and then they become demented
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what kind of disease is Pick's disease?
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a lobar degeneration disorder
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what kind of disease is Alz disease?
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a disease of associated cortex
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how is Pick's disease different from Alz disease?
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Alz affects ALL the lobes of the CNS
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what is decreased in people with depression?
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NE, serotonin, or both
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what structure of the brain makes NE?
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locus ceruleus
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what structure of the brain makes serotonin?
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dorsal raphe nucleus
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stress causes an increase of what hormone that, in turn, causes the release of what other hormone?
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ACTH, causes release of cortisol
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what is the generic name for prozac?
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fluoxetine
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what is the generic name for celexa?
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citalopram
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what is the generic name for lexapro?
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escitalopram
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what is the generic name for zoloft?
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sertraline
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what is the generic name for paxil?
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paroxetine
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name 5 SSRIs and their side effects.
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prozac: very long half-life, significant sexual side effects
celexa: acts much quicker, least amount of sexual side effects lexapro: acts quickly and has few sexual side effects zoloft: causes diarrhea, and sexual side effects paxil: sexual side effects |
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what is the generic name for wellbutrin? what does this drug do?
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buproprion; increases both NE and dopamine while countering sexual side effects from SSRIs
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name 3 serotonin and NE reuptake blockers.
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remeron
effexor cymbalta |
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what is the generic name for remeron?
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mirtazepine
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what is the generic name for effexor?
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venlafaxine
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what is the generic name for cymbalta?
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duloxetine
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what 2 drugs are used for suicide prevention?
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lithium and clozaril
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what are the 5 contraindications for ECT?
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incranial mass
recent CVA recent MI osteoporosis decreased cognitive abilities |
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what does succinylcholine do?
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blocks neuromuscular functioning
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what are the 2 predictors for success with ECT?
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total seizure time of 226 seconds
improved score on a Folstein mini mental mental state exam |
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what produces acetylcholine and degenerates in Alz disease?
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nucleus basalis of meynert
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what pathway terminates in the red nucleus?
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the dentatorubrothalamic pathway of the superior cerebellar peduncle
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what are the 2 parts of the red nucleus? what do they give rise to or send axons to?
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caudal red nucleus: gives rise to the crossed rubrospinal tract
rostral red nucleus: neurons send axons up to the ventralis lateralis |
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what frontal-subcortical circuit, when damaged, results in executive dysfunction?
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dorsolateral prefrontal circuit
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what frontal-subcortical circuit, when damaged, results in disinhibition or mood lability?
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orbitofrontal circuit
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what frontal-subcortical circuit, when damaged, results in apathy/abulia?
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anterior cingulate circuit
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