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18 Cards in this Set
- Front
- Back
What are 4 epithelial hyperplasia type presentations of HPV?
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Focal Epithelial hyperplasia
Squamous Papilloma Verruca Vulgaris Condyloma accuminatum (3) |
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Describe Focal Epithelial Hyperplasia?
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Caused by HPV 13 and 32 - multiple soft non-tender papules that can cluster together to give a cobblestone appearance. Usually normal in colou, found on labial buccal and lingual mucosa.
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What is the histology of Focal Epithelial Hyperplasia?
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Broad club-shaped rete ridges, with later fusion. Mitosoid bodies.
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What is the treatment for Focal Epithelial Hyperplasia?
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Often spontaneous regression, but simple surgical excision for diagnostic/aesthetic purposes.
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Describe Squamous Papilloma?
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Most common benign epithelial neoplasm seen intraorally. Solitary lesion typically found on soft palate/uvula or tongue.
Finger like fronds, usually pedunculated. Range of colours (red to white) |
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What is the histology of Squamous Papilloma?
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Orthokeratinized or parakeratinised. Papillary proliferation of surface epithelium. Finger like projections of fibrous connective tissue that support the epithelial proliferation.
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What is the treatment for Squamous Papilloma?
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Conservative excision, including base. Prognosis is excellent, recurreneces uncommone.
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Is there a risk of malignant transformation with Squamous Papilloma?
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No
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What does Verruca Vulgaris look like? Who does it frequently affect and where?
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Sessile, exophytic, papillary lesion. Can be multiple. Red border, white dry lumpy middle
Frequently effects children - hands and facial skin |
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Whats the treatment for Verruca Vulgaris?
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Spontaneous regression common in kids. Excision, cryotherapy, keratolytic agents can be used. May recur.
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Condyloma Acuminatum look like?
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Oral lessions, multiple, seeile, cauliflower surface
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What is it caused by and known as?
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HPV 6, 11, 16 and 18
Know as Venereal Warts |
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What is the treatment for Condyloma Acuminatum?
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Excision, cryotherapy, laser excision.
Recurrence is common - 30% after each treatment episode. |
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What is Condyloma Acuminatum associated with?
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Squamous cell carcinoma of the uterine cervix
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What is the histology of Mulluscum Contagiosum?
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Lobular proliferation of surface epithelium with basophillic viral filled molluscum bodies in the cells
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What is Molluscum Contagiosum caused by and what does it look like?
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DNA poxvirus
Multiple pink papules affect the skin of the neck, or genitalia. Each papule has a central core or depression |
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What is the treatment of Molluscum Contagiosum?
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Curettage or liquid Nitrogen, although they often resolve spontaneously in immune competent hosts in 6-9 monhts
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What is Hairy Leukoplakia caused by, look like, and tx?
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Epstein-Barr virus, often superimposed candidiasis.
Non removale white plaques of the lateral tongue No tx necessary |