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39 Cards in this Set

  • Front
  • Back
ECHO stands for?
Economic, Clinical and Humanistic Outcomes
Define Pharmacoeconomics
the descriptions and analysis of the costs and consequences of pharmaceutical and pharm services and its effect on the individ., health care systems, and society
Economic outcomes focuses on what?
The direct, indirect, and intagible costs compared with the consequences of medical treatment alternatives
Humanistic outcomes focuses on what?
Consequnces of disease or treatment on patient functional status, or quality of life.
Clinical outcomes focuses on what?
medical events that occur as a result of disease or treatment
What is the difference between direct medical and nonmedical costs?
Direct Medical costs - cost incurred for for medical prodcuts and services used for the prevention, detection, and treatment of a disease.

Direct non-medical - cost for nonmedical services that are a RESULT of a disease or illness, but do NOT require purchasing of medical serivces
Pharmacoecomnic evaluation is based on ____
balancing consequences and and costs
Define indirect costs
Costs that results form morbidity and mortality
Morbidity - incurred from missing work which is lost of productivity
Mortality - costs due to premature death
Distinguish between positive and negative consequences of economic assessments?
Postive consequences may translate into life years gained, disability days avoided, health and well-being.

Negative consequences included harmful side effect, exacerbations of the disease, drub toxicty, treatment failure, and death
How is internediate consequences difference from final consequence?
Intermediate are used to demonstraet clinical efficacy becuase their uses helps to lessen the costs and time reuqired to perform a clinical trials.

Also used in cost-effectiveness analyses predictive of final consequences of interest.
What is the difference between partial and full economic evalauations?
Full economic evaluation examine the cost of consequences of the entire program and treamtent - usually comparing one more treatment alternatives.

Partial eval include a simple tabluation of the outcomes or resrouces consumed.
Give an example of a partial evaluation?
1. Cost Analyses
2. Efficacy evaluations
3. Cost - outcome analysis
Define Cost MInimization Analysis
Only compares the costs benefits of therapeutic treatments; its job is to find the least costly treatment alternative. It is assumed that they are therapeutically equivalent. If equivalency can't be established, another method should be used.
Define Cost of Illness
Measures the direct and indirect cost of a particular diease or illness
Define Cost-Benefit Analysis
Compares the costs of benefits of alternative treatments and programs. Expressed as a cost - to -benefits ratio.
What is the difference between direct medical and nonmedical costs?
Direct Medical costs - cost incurred for for medical prodcuts and services used for the prevention, detection, and treatment of a disease.

Direct non-medical - cost for nonmedical services that are a RESULT of a disease or illness, but do NOT require purchasing of medical serivces
Pharmacoecomnic evaluation is based on ____
balancing consequences and and costs
Define indirect costs
Costs that results form morbidity and mortality
Morbidity - incurred from missing work which is lost of productivity
Mortality - costs due to premature death
Distinguish between positive and negative consequences of economic assessments?
Postive consequences may translate into life years gained, disability days avoided, health and well-being.

Negative consequences included harmful side effect, exacerbations of the disease, drub toxicty, treatment failure, and death
How is internediate consequences difference from final consequence?
Intermediate are used to demonstraet clinical efficacy becuase their uses helps to lessen the costs and time reuqired to perform a clinical trials.

Also used in cost-effectiveness analyses predictive of final consequences of interest.
What is the difference between partial and full economic evalauations?
Full economic evaluation examine the cost of consequences of the entire program and treamtent - usually comparing one more treatment alternatives.

Partial eval include a simple tabluation of the outcomes or resrouces consumed.
Give an example of a partial evaluation?
1. Cost Analyses
2. Efficacy evaluations
3. Cost - outcome analysis
Define Cost MInimization Analysis
Only compares the costs benefits of therapeutic treatments; its job is to find the least costly treatment alternative. It is assumed that they are therapeutically equivalent. If equivalency can't be established, another method should be used.
Define Cost of Illness
Measures the direct and indirect cost of a particular diease or illness
Define Cost-Benefit Analysis
Compares the costs of benefits of alternative treatments and programs. Expressed as a cost - to -benefits ratio.
Cost effectiveness analysis
Method to compare alternatives, or programs where cost is measured in monetary terms and consequences are measured in units.
Define Cost-Utility analysis (CUA)
An anylsis that adjusts (reduces) future costs and consequences to reflect present fiscal values
How is CUA normally expressed?
It's expressed and cost per QALY gained, or some other health state utility measurement.
What are the different techniques for Analysis?
Discounting
Sensitivity Analysis
Decision Analysis
Incremental Cost Analysis
What type of analysis would be performed to help manage uncertainty in an economic evaluation? To help reveal a threshold value for changing a drug-use decision?
Sensitivity Analysis
When should discounting be performed?
f the cots and consequences of program and treatment alternatives accrue during different periods within one year.
Define decision analysis
It's a technique often used in pharmacoeconomic evaluations to structure the logical and chronological order of the analysis
Describe Incremental Cost Analysis
Focus on the additional costs and additional clinical outcomes of alternative strategies

Used to answer the question, "Is the extra effoert woth the extra cost?"
When making decisions based on Medicaid or Medicare formulary, which perspectives should be the dominant one?
The government or societal perspective'
Who perspective should be considered when discussing a drug's quality of life and co-payment costs?
The Patient's perspective
Whose perspective is dominant in countries with a nationalized medical system?
Society's perspective
The science of testing questionnaires to measure attributes of individuals is called what?
Psychometrics
What are the 2 psychometric properties that must be included in any measurement scale or instrument?
Reliability - relationship between variation and random error

Validity - the extent to which differences in scale scores reflect the true difference in the individuals studied.
What are 2 practical concerns of the critics o use of HRQOL assessments in individual patient care?
1. respondent burden
2. reliability of scores obtained form shorter questionnaires