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5 Cards in this Set
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Uses include PE, DVT, MI, Arterial thrombosis and occluded shints
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woo know this!
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What drug does the following?
Activates plasminogen*** catalyzes degradation of fibrinogen V and VII |
Streptokinase
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What drug is less antigenic then streptokinase bc it is derived from human fetal renal cells rather than from bacteria?
Works to degrade fibrin by ACTIVATING PLASMINOGEN |
Urokinase
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What drug does the following?
plasminogen activator aka Alteplase fibrin selective and so will only activate plasmin that is already bound to fibrin. instead of acting as thrombolytic all over the body like other agents it only targets areas that have already begun to form clots. Does not have as many complications*** Very effective in MI, PE, and acute ischemic stroke |
tPA
Tissue Plasminogen Activator |
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Thrombolytics work by......
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lyse or break down already formed clots :)
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