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14 Cards in this Set
- Front
- Back
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What is seborrheic keratosis?
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-at or beyond middle age
-benign -usually on trunk -round, flat, coin-like plaques that feel velvety/granular/greasy and often look stuck on |
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Describe keratoacanthoma
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-male>female, especially in Caucasians
-flesh-colored dome-shaped nodule with a keratin-filled plug |
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Describe actinic keratosis
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-too much sun
-dysplasia before malignant CA -some have cutaneous horn |
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Basal cell carcinoma
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SUN!!!
slow gorwing, rarely metastasizes pearly gray with telangiectasias |
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Squamous cell carcinoma
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-SUN!!!
-male>female -too much UV-->DNA damage-->damages Langerhans cells--> therefore no surveillance-->allows malignant cells to grow -#1 skin cancer on sun-exposed sites in older adults |
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Melanoma
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-SUN!!
-most are cured by excisional removal -most imp sign=change in color -may be pruritic -risk facotrs: sun, pre-existing nevus, genetics, carcinogens |
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Bowen disease
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-Genital region
-thickened, gray-white plaques -related to HPV, typically type 16 -10% transition to squamous cell CA |
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What part of the skin loses its attachment in pemphigus?
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loss of attachment between keratinocytes and fluid fills within the spaces, resulting in vesicles
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What is the pathology behind pemphigoid?
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Antibodies develop against adhesion sites between basal cells and basement membrance; this causes loss of attachment, fluid fills the area, lifting the entire cutaneous epithelial layer from its basement membrane-->Bullae
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What disease has a rash that takes on a "christmas tree pattern" and is often preceded by a herald patch?
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Pityriasis rosea
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What fungal species are most likely to cause Tinea versicolor?
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Pityrosporum orbicularis/Pityrosporum ovale/Malassezia furfur
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If a skin scraping of a rash under microscope appears as a mixture of hyphae and spores, what disease is likely?
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Tinea versicolor
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A xanthoma is a cholesterol accumulation in what layer o skin?
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dermis
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With what syndrome is a cavernous hemangioma/Port Wine stain associted?
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Sturge-Weber-->congenital disease with faulty mesoderm and ectoderm development, resulting in hemangiomas associated with meninges. Seizures!
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