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8 Cards in this Set

  • Front
  • Back
Tissue type matching is not done for blood transfusions because?
RBC are not nucleated hence don't contain Class I MHC or HLA type I molecules.

they have type A or type B
Mutation in what predisposes a person to hemochromatosis?
HLA-A3
Mutation in what predisposes a person to anklyosing spondylitis and reactive arthritis (Reiter's?)?
HLA-B27
HLA defect seen in mutiple sclerosis?
HLA-DR2

think multiple sclerosis is two works hence 2
HLA defect seen in SLE?
HLA-DR3

SLE is three letters!!
What HLA defect is seen in Type I DM?
HLA- DR 2,3,4

type 1...then 2,3,4
HLA defect seen in Rheumotoid arthritis?
Dr14, Dw4, DR 4
What chrosome is the MHC gene found?
chromosome 6..

MHC when expressed forms HLA molecules.