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32 Cards in this Set
- Front
- Back
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What is the DOC combo for HCV?
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Ribavarin (mimics GTP) + Interferon (inhibits RNA translation/induces MHC-1 expression)
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How does the mechanism of ganciclovir differ from acyclovir?
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Acyclovir requires viral thymidine kinase --> doesn't treat CMV
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What class of anti-virals are nevirapine, delavridine and efavirenz?
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NNRTIs
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What os the DOC for severe adenovirus infections and smallpox?
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cidofovir
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What levels of Ca++ and alkaline phosphatase would be expected with osteoporosis?
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Normal Ca++
Normal Alk Phosphatase |
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What is the distinctive lab finding and x-ray appearance of Paget's dz?
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Severely high alkaline phosphatase, mosaic pattern on x-ray
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What type of cartilage is found in intervertebral discs and menisci?
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Fibrocartilage (Type I collagen)
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What are the malignant cartilage and bone tumors?
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the sarcomas (osteosarcoma, Ewing's sarcoma, chondrosarcoma)
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What bone tumor is associated with Codman's triangle?
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Osteosarcoma
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What dz is caused by X-linked absence of dystrophin protein?
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Duchenne Muscular Dystrophy
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What are the 3 neural crest tumors?
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meningioma, schwannoma, neurofibroma (all benign)
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Lewy bodies are associated with what dz?
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Parkinson's
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oligoclonal bands are characteristic of what dz?
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MS
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Which pituitary problem leads to panhypopituitarism?
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Sheehan's Syndrome
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Which adenoma produces mineralocorticoids?
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Conn
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What is Plummer's dz?
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Nodular toxic goiter w/ hyperplasia, hypertrophy and colloid accumulation
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What malignant thyroid tumor is a/w radiation exposure?
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papillary CA
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What are the secondary causes of hyperparathyroidism?
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chronic renal failure, vit D def
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what is the cause of MODY
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glucokinase defect
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Which MEN is a/w tumors in the adrenal cortex?
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MEN I
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what are the vast majority of skin tumors?
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basal cell carcinoma (80%) - low metastatic potential
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what is the difference between pemphigus and pemphigoid?
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Pemphigus = IgG Ab against desmosomes --> intraepidermal blister --> positive nikolsky's sign
Pemphigoid = IgG Ab against hemidesmosomes --> seperation at epidermal basement membrane --> negation Nikolsky's sign |
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what toxin produces "honeycomb" pneumonitis?
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Cadmium
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What is the PAS stain used for?
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glycogen, mucopolysaccharides
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Lactobaccilus and Streptococci are normal flora of what organ?
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Vagina
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Which organism is a/w endocarditis post-dental procedure?
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Strep. viridans
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What is the Rib Rules of Three?
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T1-T3 --> Transverse process level with spinous process
T4-T6 --> Transverse process halfway to superior spinous T7-T9 --> Transverse process level w/ superior spinous process T10 --> like T7-9 T11 --> like T4-6 T12 --> like T1-3 |
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What are the typical ribs?
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3-10
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What is the motion of the ribs
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1-5 --> Pump handle
6-10 --> bucket handle 11-12 --> caliper |
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What are the primary muscles of respiration?
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Diaphragm, Intercostals
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What rib is at the inferior angle of the scapula?
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T7
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What is the Hardy-Weinberg Equlibrium?
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(p- + 2pq + q- = 1)
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