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65 Cards in this Set
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- Back
What 3 fungi can cause dermatophtosis (pruritic papules, vesicles, brocken hair, and nails) may also see a red ring with central clearing?
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Epidermophyton
Trichophyton Microsporum |
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What fungi is the main cause of Tinea Versicolor?
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Malassezia furfur***
see spagehetti and meatballs on micro slide lol |
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If on a slide you saw a tree like shaped pus draining abscess in the subcutaneous layer what is this?
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Petrollidium, Madurella
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If you were asked to pick out the Cigar shaped budding yeast on a slide, and the person tells you they got this from a wound (being stuck by a rose) what is it?
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Sporothrix shenkii
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This fungi is spread by inhalation*** via endospores. It lives in soil and is most found in the southwest USA. Has a very high death rate
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Coccidoidomycosis
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What 3 fungi can cause dermatophtosis (pruritic papules, vesicles, brocken hair, and nails) may also see a red ring with central clearing?
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Epidermophyton
Trichophyton Microsporum |
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What fungi is the main cause of Tinea Versicolor?
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Malassezia furfur***
see spagehetti and meatballs on micro slide lol |
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If on a slide you saw a tree like shaped pus draining abscess in the subcutaneous layer what is this?
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Petrollidium, Madurella
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If you were asked to pick out the Cigar shaped budding yeast on a slide, and the person tells you they got this from a wound (being stuck by a rose) what is it?
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Sporothrix shenkii
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This fungi is spread by inhalation*** via endospores. It lives in soil and is most found in the southwest USA. Has a very high death rate
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Coccidoidomycosis
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This is an infection seen in immunocompromised people. it is non-disseminated an see fever, cough, arthralgias, and a positive skin test?
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Valley fever
aka Desert Rheumatism; San Joaquin Valley Fever |
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This fungi is from the Ohio and mississippi river valley.
inhale spores, macrophages engulf them, spores become oval budding yeast, these live in soil, from bat and bird shit*** looks like pulmonary TB, spreads to liver and spleen, and heals by calcification |
Histoplasmosis
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Found in Ohio and Mississippi areas
great lakes found in moist soil and inhaled, cause skin and bone ulcerative granulomas MOST COMMON IN THE FALL |
BLASTOMYCOSIS
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DEVELOP PSEUDOHYPHAE IN TISSUE
esp common from bird/pigeon droppings. this is an AIDS defining illness**** Positive with an INDIA INK STAIN**** |
Cryptococcosis Neoforms
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This produces germ tubes and pseudohyphae during infections****
Vulvovaginitis and Thrush*** esophagitis, intertrigo, and endocarditis |
Candida albicans
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This is a common mold in decaying vegetation
see a V-shaped septate hyphae grow in WARM body cavitis lung cavitations caused by TB or Wegner's or in deep recesses of sinuses. Key word are Fungus balls*** Allergic Bronchopulmonary --> might see asthma + high IgE titers |
Aspergillosis
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This fungi does not grow in the body but makes a aflatoxin on cereal, grains, and oats.
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Aspergillus flavus
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This attacks pts with weakened immune systems
inhaled multiply in blood vessels walls, found in the GI, lungs Pts at highest risk are Diabetics, burn victims, and who have leukemia. Non-septae hyphae are seen with right angled branches |
mucormycosis: Mucor or Rhizopus
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what are the 2 major blood protozoa?
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babesia and Plasmodia
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the lifecycle of malaria....know it!
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what is the only life cycle of the malarial plasmodia that can survive in RBCs?
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Merzoites
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What is the only stage of malaria that is consumed by a mosiquto and thus is the ONLY way malaria is transmitted?
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gametocytes
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Is all development of malaria in the human or animal sexual or asexual?
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All in human and animal is ASEXUAL
only SEXUAL reproduction is in Mosquito |
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What is the Tx for malaria?
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chloroquine
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what is Tx for chloroquine resistent malaria?
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Doxycycline or Tetracycline or Clindamycin
+ Quinine |
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If you are treating P.vivax what drug must you add to the combination of drugs?
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Primaquine
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What malaria will cause black urine due to hemolysis of RBC debris?
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Plasmodium falciparum***
worst of the malaria bc can infect all stages of RBC lifecycle. See P.vivax and P.ovale can only infect immature RBCs This black urine is called BLACK WATER FEVER |
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What is the only Malaria to infect RBCs within 72 hr cycle?
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Plasmodium Malariae
this is also the only malaria to infect MATURE RBCs |
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What can cause a malaria like syndrome?
But is transmitted by the tick found in northeast US and California? on blood smear will see trophozoites in RBCs occuring in pairs or tetrads? |
Babesia***
Tx: Quinine + Clindamycin |
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What is a protozoa that is transmitted by inhalation, casuses a diffuse interstitial pneumonia, commonly affects AIDS and Neonates....immunocompromised. is 100% fatal is not treated and 50% fatal even with Tx. See alveolar cysts and frothy exudates, disseminates to liver, spleen, and bone marrow.
Dx: Bronchial lavage with silver stain Tx: TMP-SMX |
Pneumocystitis jiroveci
Think pneumo = lung. Said to make sure you know that the Dx is made by silver stain and not by X-ray*** Also look for the grounf glass appearance aka frosted glass sign....wtf i know lol |
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This is a protozoa transmitted via cats***
you will see multiple ring lesions in the brain aquired from contaminated food or inhalation onto the GI mucosa Esp dangerous in pregnant women |
Part of the TOUCH syndrome
Toxoplasma gondii Tx: Pyrimethamine + Sulfadiazine + Leucovorin |
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What protoza is transmitted by the SAND FLY?
reservior are dogs, foxes, rodents. Causes Kala Azar** which if untreated causes Black Sickness |
Leishmania donovani
sanfly bites, then reticuloendothelial system causes Kala-Azar. If this is untreated you will see fever, wt loss, and HYPERpigmentation aka Black Sickness :( Tx: Stibogluconate is cutaneous Amphotericin B if systemic |
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What causes mucocutaneous ulcers and destruction of the nasal cartilage?
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Leishmania brasiliensis
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What causes a red papule at the bite which enlarges with satellite lesions causing ulcers which coalesce. 100% mortality without Tx.
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Leshmani mexicana or Leishmania tropica
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What causes Chagas disease?
The vector is from the kissing bug might cause arrythmias or toxic megacolon / mega esophagus |
Trypanosoma cruzi
Tx: Nifurtimox |
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Vector is the Tse-Tse fly***
reservio is the human found in west africa along water ways Causes AFRICAN SLEEPING SICKNESS eventually after infection enter lymph nodes and brain Present with fever that spikes every 2 weeks, then lyphadenopathy, and finally encephalopathy with headache, sleered speech, mood changes, followed by death and common |
Trypanosoma brucei
Tx: Suramin or Pentamidine If the person has encephalitis though Tx with Melarsoprol or Eflornithine |
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This is Dx with a Wet Mount or Ab detection
the cysts have 4 nuclei the disease is spread via cysts Trophozoite is the adult form Unique is cysts divide into 8 trophozoites which cause a tear drop or flask-shaped ulcer in the colon and blood diarrhea. Nothing kills these not boiling water or bleach |
Entamoeba histolytica
only way to kill these is by iodine or filters |
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this Protozoa has a 4 nuclei cyst
also has flagella in trophozoite form infects the sm intesting associated with hickers and campers drinking stream water**** Foul smelling diarrhea Dx: String test, Wet mount, Ab |
Giardia lamblia
check the poo** |
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causes severe diarrhea in AIDS and immunocompromised
infects sm intestine severe watery diarrhea and NON-bloody CAN GET VIA TAP WATER AND PUBLIC WATER SOURCE Dx: AF stain of fecal smear detects oocytes*** |
Cryptospordium
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these are trophozoites with 1 nuclei and 4 flagella with an undulating membrane and is pear shaped***
Dx: wet mount causes an STD* |
Trichomonas vaginalis
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This is an amoeba caused by swimming in the warm water in Southern US
enters the nasal cavity and passes thru the cribiform plate to cause meningoencephalitis RAPIDLY FATAL**** |
Naegleria fowleri
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An amoeba causes keratits in health contact lens users
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Acanthamoeba castellanii
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Schistosomas are all Blood Flukes and are types of flatworms. They are all carried in snails.
All cause splenomegaly** Describe the lifecycle |
free swimmin immature form in water enter via skin
enter blood enter liver MATURE into adults Migrate to mesenteric vessels |
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What flukes are in:
veins of colon? Veins of sm intestine? Veins of bladder via venous plexus of rectum |
Veins of colon - mansoni
veins of sm intestine - japonicum veins of bladder via plexus of rectum - hematobium |
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What fluke is associated with bladder bleeding and see blood in the urine.
also might cause bladder ca? |
Hematobium
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What fluke is from ingestion of contaminated fish
cysts form exist the small intestine and move retrograde through the bile duct MATURE in bile duct, mate, and eggs leave with stool leads to cholangitis and chronic infection can lead to cholangiocarcinoma |
Clonorchis sinensis
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ingested contaminated crab
cysts exist sm intest migrate through the diaphragm and enter the lung** MATURE into adults make eggs are coughed up bloody cough and chronic....mimic TB*** |
Paragonimus Westermani
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What tapeworm is known as the PIG TAPEWORM?
Settles in brain and eyes and develop into cysticerci |
Taenia solium
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This is known as the beef tapeworm***
sometimes worms emerge out of anus |
Taenia saginata
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This is known as the fish tapeworm
consumes B12 and causes B12 deficiecy? |
Diphyllobothrium latum
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The DOG tapeworm
more common in kids.....who else would ingest feces lol eggs develop in liver, lung, and brain |
Echinococcus granulosus
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The most common tapeworm in USA
different from other tapeworms DO NOT need intermediate animal and one infection causes hundreds to thousands of worms into intestine Most common in southeast US esp in children |
Hymenolepsis nana
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The most common tapeworm in cats and dogs
get it from eating infected fleas from infected cats or dogs most infections are asymptomatic but may cause diarrhea and/or prutitis ani (itchy butt) |
Dipylidium caninum
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This is a ROUNDWORM (Nematode)
aka "pinworm" #1 helminth in US Dx: you do the scotch tape test perianal pruritis esp at night |
Enterobius vermicularis
ingest eggs hatch in sm intest mature move to colon mate At night female migrate to anus to lay eggs |
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The largest intestinal Nematode***
Dx: detect eggs in stool via O&P Has to visit the intestine 2 times to get the infection you ingest eggs migrate to lungs enter bronchi and trachea coughed up and swallowed go to small intest mature to adult form now move to colon mate and produce eggs passed in stool |
ascaris lumbricoides
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American Hookworm aka New workd hookworm
found in US and tropics causes an iron deficient anemia larvae penetrate skin and enter blood enter the lungs ascend up are swallowed then go to sm intest MATURE feed on blood in the GI tract common in barefoot |
Necator americanus
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Old world hookworm
tropical areas has the same pathogenesis as Necator americanus but has teeth!!!! |
Ancylostoma duodenale
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causes trichinosis
eastern europe, west africa, US fever, myalgia, periorbital edema, eosinophilia, +/- CNS and cardiac symptoms get from eating raw or undercooked pork/bear/seal can enter skeletal muscle and develop into cysts esp trapezius** |
Trichinella spiralis
can also cause arrhythmias of heart |
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Causes filariasis which is massive lymph node obstruction with limb edema
ELEPHANTIASIS vector: mosquito (+) blood test bc |
Wuchereria bancrofti
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Causes onchocerciasis aka LIZARD SKIN
BLINDNESS - RIVER BLINDNESS vector: blackfly found in Africa and Central America Dx: (-) blood test - does not enter blood (+) skin test - migrates through skin |
Onchocerca volvulus
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Causes loiasis
Vector: deer fly (aka mango fly) will see adult form crawling across the conjunctiva*** found in central and west africa (+) blood test |
Loa Loa
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What of worm are taken up by the vector from the host to be retransmitted to another host?
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microfilariae
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known as guinea fire worm
causes dranunculiasis common in middle east and India LITERALLY MAKES YOUR SKIN CRAWL ingest from drinking water Dx: worm movement under skin Tx: NO meds!!! Instead roll on a stick |
Dranunculus medinensis
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causes anisakiasis
get from raw seafood via sushi and sashimi (esp salmon and red snapper) causes gastroenteritis, eosinophilia, occult blood stool, and symptoms of appendicitis |
Anisakis simplex
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causes cutaneous larvae migrans aka "creeping eruption"
from cats and dogs southern USA |
Ancylostom caninum/brazilienze
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