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65 Cards in this Set

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  • Back
What 3 fungi can cause dermatophtosis (pruritic papules, vesicles, brocken hair, and nails) may also see a red ring with central clearing?
Epidermophyton
Trichophyton
Microsporum
What fungi is the main cause of Tinea Versicolor?
Malassezia furfur***

see spagehetti and meatballs on micro slide lol
If on a slide you saw a tree like shaped pus draining abscess in the subcutaneous layer what is this?
Petrollidium, Madurella
If you were asked to pick out the Cigar shaped budding yeast on a slide, and the person tells you they got this from a wound (being stuck by a rose) what is it?
Sporothrix shenkii
This fungi is spread by inhalation*** via endospores. It lives in soil and is most found in the southwest USA. Has a very high death rate
Coccidoidomycosis
What 3 fungi can cause dermatophtosis (pruritic papules, vesicles, brocken hair, and nails) may also see a red ring with central clearing?
Epidermophyton
Trichophyton
Microsporum
What fungi is the main cause of Tinea Versicolor?
Malassezia furfur***

see spagehetti and meatballs on micro slide lol
If on a slide you saw a tree like shaped pus draining abscess in the subcutaneous layer what is this?
Petrollidium, Madurella
If you were asked to pick out the Cigar shaped budding yeast on a slide, and the person tells you they got this from a wound (being stuck by a rose) what is it?
Sporothrix shenkii
This fungi is spread by inhalation*** via endospores. It lives in soil and is most found in the southwest USA. Has a very high death rate
Coccidoidomycosis
This is an infection seen in immunocompromised people. it is non-disseminated an see fever, cough, arthralgias, and a positive skin test?
Valley fever
aka Desert Rheumatism; San Joaquin Valley Fever
This fungi is from the Ohio and mississippi river valley.
inhale spores, macrophages engulf them, spores become oval budding yeast,

these live in soil, from bat and bird shit***

looks like pulmonary TB, spreads to liver and spleen, and heals by calcification
Histoplasmosis
Found in Ohio and Mississippi areas
great lakes
found in moist soil and inhaled, cause skin and bone ulcerative granulomas

MOST COMMON IN THE FALL
BLASTOMYCOSIS
DEVELOP PSEUDOHYPHAE IN TISSUE

esp common from bird/pigeon droppings.

this is an AIDS defining illness****

Positive with an INDIA INK STAIN****
Cryptococcosis Neoforms
This produces germ tubes and pseudohyphae during infections****

Vulvovaginitis and Thrush***
esophagitis, intertrigo, and endocarditis
Candida albicans
This is a common mold in decaying vegetation
see a V-shaped septate hyphae
grow in WARM body cavitis
lung cavitations caused by TB or Wegner's or in deep recesses of sinuses.

Key word are Fungus balls***
Allergic Bronchopulmonary --> might see asthma + high IgE titers
Aspergillosis
This fungi does not grow in the body but makes a aflatoxin on cereal, grains, and oats.
Aspergillus flavus
This attacks pts with weakened immune systems
inhaled
multiply in blood vessels walls, found in the GI, lungs

Pts at highest risk are Diabetics, burn victims, and who have leukemia.
Non-septae hyphae are seen with right angled branches
mucormycosis: Mucor or Rhizopus
what are the 2 major blood protozoa?
babesia and Plasmodia
the lifecycle of malaria....know it!
what is the only life cycle of the malarial plasmodia that can survive in RBCs?
Merzoites
What is the only stage of malaria that is consumed by a mosiquto and thus is the ONLY way malaria is transmitted?
gametocytes
Is all development of malaria in the human or animal sexual or asexual?
All in human and animal is ASEXUAL

only SEXUAL reproduction is in Mosquito
What is the Tx for malaria?
chloroquine
what is Tx for chloroquine resistent malaria?
Doxycycline or Tetracycline or Clindamycin
+
Quinine
If you are treating P.vivax what drug must you add to the combination of drugs?
Primaquine
What malaria will cause black urine due to hemolysis of RBC debris?
Plasmodium falciparum***

worst of the malaria bc can infect all stages of RBC lifecycle. See P.vivax and P.ovale can only infect immature RBCs

This black urine is called BLACK WATER FEVER
What is the only Malaria to infect RBCs within 72 hr cycle?
Plasmodium Malariae
this is also the only malaria to infect MATURE RBCs
What can cause a malaria like syndrome?
But is transmitted by the tick
found in northeast US and California?
on blood smear will see trophozoites in RBCs occuring in pairs or tetrads?
Babesia***

Tx: Quinine + Clindamycin
What is a protozoa that is transmitted by inhalation, casuses a diffuse interstitial pneumonia, commonly affects AIDS and Neonates....immunocompromised. is 100% fatal is not treated and 50% fatal even with Tx. See alveolar cysts and frothy exudates, disseminates to liver, spleen, and bone marrow.
Dx: Bronchial lavage with silver stain
Tx: TMP-SMX
Pneumocystitis jiroveci

Think pneumo = lung. Said to make sure you know that the Dx is made by silver stain and not by X-ray***

Also look for the grounf glass appearance aka frosted glass sign....wtf i know lol
This is a protozoa transmitted via cats***
you will see multiple ring lesions in the brain
aquired from contaminated food or inhalation onto the GI mucosa
Esp dangerous in pregnant women
Part of the TOUCH syndrome

Toxoplasma gondii

Tx: Pyrimethamine + Sulfadiazine + Leucovorin
What protoza is transmitted by the SAND FLY?
reservior are dogs, foxes, rodents.
Causes Kala Azar** which if untreated causes Black Sickness
Leishmania donovani

sanfly bites, then reticuloendothelial system causes Kala-Azar. If this is untreated you will see fever, wt loss, and HYPERpigmentation aka Black Sickness :(

Tx: Stibogluconate is cutaneous
Amphotericin B if systemic
What causes mucocutaneous ulcers and destruction of the nasal cartilage?
Leishmania brasiliensis
What causes a red papule at the bite which enlarges with satellite lesions causing ulcers which coalesce. 100% mortality without Tx.
Leshmani mexicana or Leishmania tropica
What causes Chagas disease?
The vector is from the kissing bug
might cause arrythmias or toxic megacolon / mega esophagus
Trypanosoma cruzi

Tx: Nifurtimox
Vector is the Tse-Tse fly***
reservio is the human
found in west africa along water ways
Causes AFRICAN SLEEPING SICKNESS
eventually after infection enter lymph nodes and brain
Present with fever that spikes every 2 weeks, then lyphadenopathy, and finally encephalopathy with headache, sleered speech, mood changes, followed by death and common
Trypanosoma brucei

Tx: Suramin or Pentamidine

If the person has encephalitis though Tx with Melarsoprol or Eflornithine
This is Dx with a Wet Mount or Ab detection
the cysts have 4 nuclei
the disease is spread via cysts
Trophozoite is the adult form
Unique is cysts divide into 8 trophozoites which cause a tear drop or flask-shaped ulcer in the colon and blood diarrhea.

Nothing kills these not boiling water or bleach
Entamoeba histolytica

only way to kill these is by iodine or filters
this Protozoa has a 4 nuclei cyst
also has flagella in trophozoite form
infects the sm intesting
associated with hickers and campers drinking stream water****
Foul smelling diarrhea
Dx: String test, Wet mount, Ab
Giardia lamblia
check the poo**
causes severe diarrhea in AIDS and immunocompromised
infects sm intestine
severe watery diarrhea and NON-bloody
CAN GET VIA TAP WATER AND PUBLIC WATER SOURCE
Dx: AF stain of fecal smear detects oocytes***
Cryptospordium
these are trophozoites with 1 nuclei and 4 flagella with an undulating membrane and is pear shaped***
Dx: wet mount
causes an STD*
Trichomonas vaginalis
This is an amoeba caused by swimming in the warm water in Southern US
enters the nasal cavity and passes thru the cribiform plate to cause meningoencephalitis
RAPIDLY FATAL****
Naegleria fowleri
An amoeba causes keratits in health contact lens users
Acanthamoeba castellanii
Schistosomas are all Blood Flukes and are types of flatworms. They are all carried in snails.
All cause splenomegaly**
Describe the lifecycle
free swimmin immature form in water enter via skin
enter blood
enter liver
MATURE into adults
Migrate to mesenteric vessels
What flukes are in:
veins of colon?
Veins of sm intestine?
Veins of bladder via venous plexus of rectum
Veins of colon - mansoni
veins of sm intestine - japonicum
veins of bladder via plexus of rectum - hematobium
What fluke is associated with bladder bleeding and see blood in the urine.
also might cause bladder ca?
Hematobium
What fluke is from ingestion of contaminated fish
cysts form exist the small intestine and move retrograde through the bile duct
MATURE in bile duct, mate, and eggs leave with stool
leads to cholangitis and chronic infection can lead to cholangiocarcinoma
Clonorchis sinensis
ingested contaminated crab
cysts exist sm intest
migrate through the diaphragm and enter the lung**
MATURE into adults make
eggs are coughed up
bloody cough and chronic....mimic TB***
Paragonimus Westermani
What tapeworm is known as the PIG TAPEWORM?
Settles in brain and eyes and develop into cysticerci
Taenia solium
This is known as the beef tapeworm***
sometimes worms emerge out of anus
Taenia saginata
This is known as the fish tapeworm
consumes B12 and causes B12 deficiecy?
Diphyllobothrium latum
The DOG tapeworm
more common in kids.....who else would ingest feces lol
eggs develop in liver, lung, and brain
Echinococcus granulosus
The most common tapeworm in USA
different from other tapeworms
DO NOT need intermediate animal
and one infection causes hundreds to thousands of worms into intestine
Most common in southeast US esp in children
Hymenolepsis nana
The most common tapeworm in cats and dogs
get it from eating infected fleas from infected cats or dogs
most infections are asymptomatic but may cause diarrhea and/or prutitis ani (itchy butt)
Dipylidium caninum
This is a ROUNDWORM (Nematode)
aka "pinworm"
#1 helminth in US
Dx: you do the scotch tape test
perianal pruritis esp at night
Enterobius vermicularis

ingest eggs
hatch in sm intest
mature
move to colon
mate
At night female migrate to anus to lay eggs
The largest intestinal Nematode***
Dx: detect eggs in stool via O&P
Has to visit the intestine 2 times to get the infection
you ingest eggs
migrate to lungs
enter bronchi and trachea
coughed up and swallowed
go to small intest
mature to adult form now
move to colon
mate and produce eggs passed in stool
ascaris lumbricoides
American Hookworm aka New workd hookworm
found in US and tropics
causes an iron deficient anemia
larvae penetrate skin and enter blood
enter the lungs
ascend up
are swallowed
then go to sm intest
MATURE
feed on blood in the GI tract
common in barefoot
Necator americanus
Old world hookworm
tropical areas
has the same pathogenesis as Necator americanus but has teeth!!!!
Ancylostoma duodenale
causes trichinosis
eastern europe, west africa, US
fever, myalgia, periorbital edema, eosinophilia, +/- CNS and cardiac symptoms
get from eating raw or undercooked pork/bear/seal

can enter skeletal muscle and develop into cysts esp trapezius**
Trichinella spiralis

can also cause arrhythmias of heart
Causes filariasis which is massive lymph node obstruction with limb edema
ELEPHANTIASIS
vector: mosquito
(+) blood test bc
Wuchereria bancrofti
Causes onchocerciasis aka LIZARD SKIN
BLINDNESS - RIVER BLINDNESS
vector: blackfly
found in Africa and Central America
Dx: (-) blood test - does not enter blood
(+) skin test - migrates through skin
Onchocerca volvulus
Causes loiasis
Vector: deer fly (aka mango fly)
will see adult form crawling across the conjunctiva***
found in central and west africa
(+) blood test
Loa Loa
What of worm are taken up by the vector from the host to be retransmitted to another host?
microfilariae
known as guinea fire worm
causes dranunculiasis
common in middle east and India
LITERALLY MAKES YOUR SKIN CRAWL
ingest from drinking water
Dx: worm movement under skin
Tx: NO meds!!! Instead roll on a stick
Dranunculus medinensis
causes anisakiasis
get from raw seafood via sushi and sashimi (esp salmon and red snapper)
causes gastroenteritis, eosinophilia, occult blood stool, and symptoms of appendicitis
Anisakis simplex
causes cutaneous larvae migrans aka "creeping eruption"
from cats and dogs
southern USA
Ancylostom caninum/brazilienze