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7 Cards in this Set
- Front
- Back
What are some GOLD agents currently used in treatment for Rheumatoid Arthritis?
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Auranofin and gold sodium thiomalate
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When is GOLD not used for RA and what is the antidote for overdose?
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Acute attacks
Dimercaprol |
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Match with the drugs:
A) Inhibits the production and secretion of tumor necrosis factor B) a phosphodiesterase inhibitor that causes TNF secretion inhibition C) a monoclonal antibody that is directed against TNF D) recombinant TNF receptor- binds TNF in bloodstrem. E) FULLY human monoclonal antibody against TNF Adalimumab Infliximab Etanercept Pentoxyfilline Thalodomide |
Adalimumab-----E
Infliximab---C Etanercept---D Pentoxyfilline---B Thalodomide---A |
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DOC for acute gout attacks
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Colchicine
works by binding tubulin , disrupting cells abiility to find to affected area, stopping mitosis, and inhibiting release of leukotrienes. Cantraindicated in pregnancy |
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How does Allopurinol work in GOUT?
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Inhibits Xanthine oxidase.
Stop using it when you start people on 6-mercaptopurine |
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Can you use Aspirin for GOUT?
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No. Even though NSAIDs are acceptable for GOUT. NOT ASPIRIN.
It competes with secretion of Uric acid at the renal transporters in PCT. |
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What drug would you use from chronic GOUT?
DOC for acute? |
Probenecid
Colchicine |