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7 Cards in this Set

  • Front
  • Back
What are some GOLD agents currently used in treatment for Rheumatoid Arthritis?
Auranofin and gold sodium thiomalate
When is GOLD not used for RA and what is the antidote for overdose?
Acute attacks

Dimercaprol
Match with the drugs:

A) Inhibits the production and secretion of tumor necrosis factor
B) a phosphodiesterase inhibitor that causes TNF secretion inhibition
C) a monoclonal antibody that is directed against TNF
D) recombinant TNF receptor- binds TNF in bloodstrem.
E) FULLY human monoclonal antibody against TNF

Adalimumab
Infliximab
Etanercept
Pentoxyfilline
Thalodomide
Adalimumab-----E
Infliximab---C
Etanercept---D
Pentoxyfilline---B
Thalodomide---A
DOC for acute gout attacks
Colchicine

works by binding tubulin , disrupting cells abiility to find to affected area, stopping mitosis, and inhibiting release of leukotrienes. Cantraindicated in pregnancy
How does Allopurinol work in GOUT?
Inhibits Xanthine oxidase.

Stop using it when you start people on 6-mercaptopurine
Can you use Aspirin for GOUT?
No. Even though NSAIDs are acceptable for GOUT. NOT ASPIRIN.

It competes with secretion of Uric acid at the renal transporters in PCT.
What drug would you use from chronic GOUT?

DOC for acute?
Probenecid

Colchicine