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16 Cards in this Set
- Front
- Back
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most effective agent for rapidly progressing RA
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GOLD
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most common SE for Gold
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dermatitis of skin and membranes
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D-penicillamine is used for
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chelating agent...not RA anymore
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steroids can reduce inflammation by inhibiting
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phospholipase A2
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thalidomide MOA
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inhibits TNF
used for HIV skin lesions, leprosy, |
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pentoxyfilline MOA and use
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phosphodiesterase inhibitor so inhibits TNF secretion
used for acute alcoholic hepatitis |
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Infliximab MOA and Use
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monoclonal antibody against TNF
use: RA, Ankl sponylitis, psoriatic arthritis, ulcerative colitis and crohns |
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etanercept MOA
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recombinant TNF receptor
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Adalimumab MOA
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fully human AB against TNF
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DOC for acute attacks of Gout
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colchicine
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MOA for colchicine
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binding tubulin, stops migration of cells to area and prevents release of leukotrienes
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allopurinol MOA
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inhibits xanthine oxidase, inhibiting uric acid production
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chronic gout treated with...
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probenecid
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probenecid competes with....
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urate at renal transporters....but ultimately inhibits reabsorption of uric acid
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what syndrome would you see chronic gout in
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lesch nyhan (XR)
dfect in HGPRT... |
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never use what in gout
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aspirin
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