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20 Cards in this Set

  • Front
  • Back
What are the 4 A's of Schizophrenia?
1. Abnormal Associations

2. Autistic Thinking/Behavior

3. Abnormal Affect

4. Ambivalence
What is ambivalence in terms of schizophrenia?
Knowing you have schizophrenia but still believing that people are following you
What is the lifetime risk of schizophrenia?
About 0.7%
In which sex does schizophrenia have a higher incidence?
Men
Is there a sex difference in prevalence, why/why not?
NO, because men die off faster with schizophrenia
What is the first phase of schizophrenia?
The "Prodromal" psychosis - period of attenuated psychotic symptoms before the onset of overt psychosis
What are 4 symptoms seen in the prodromal schizophrenia?
1. Visual/auditory illusions

2. Mild paranoid ideas or ideas of reference

3. Negative symptoms

4. Difficulty with cognition
What are the 5 characteristic symptoms of schizophrenia?
1. Delusions

2. Hallucinations

3. Disorganized speech

4. Disorganized / catatonic

5. Negative Symptoms
What must be the duration of schizophrenia to be diagnosed?
>6 months
What are the most common delusions?
Persecutory and delusions of reference (thinking innocuous stimuli pertain/are relevant to the patient)
What are the most common type of hallucinations?
Auditory
What is a current hypothesis as to the pathology of schizophrenia?
Hyperdomaminergic mesolimbic pathways lead to aberrant salience being attributed to random stimuli
What are 5 negative symptoms?
1. Alogia - Reduce verbal communication

2. Flat Affect

3. Anhedonia - reduced interest or pleasure (esp anticipatory pleasure)

4. Avolition - Reduced motivation

5. Asociality - reduced social drive and interaction
What are the 2 major mood symptoms in schizophrenia?
1. Depression

2. Anxiety
What is a major cognitive comorbidity seen in schizophrenia?
Cognitive deficits - global deficit in cognition 1-2 SD's below mean
What are the 5 areas of greatest deficit seen in schizophrenia?
1. Verbal learning and memory

2. Visual learning and memory

3. Attention

4. Speed of processing

5. Executive function
When are cognitive deficits first noticeable?
At time of first measurement (ex: 6-7 years)
When are cognitive deficits most dramatic?
Between ages 12-17
What are the 4 phases of schizophrenia?
1. Premordid phase

2. Prodromal phase

3. Psychotic phase

4. Stable Phase
Antipsychotic medications generally only treat what symptoms?
Positive symptoms