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5 Cards in this Set

  • Front
  • Back
Four Groups of Postraumatic Stress Syndromes
1. Dissociation (ASD only?)
2. Intrusion
3. Avoidance
4. Hyperarousal
4 Useful predictors of PTSD
1.***Persistence of PT symptoms for >10-14 days
2. Immediate pre-trauma psychiatric history
3. Previous trauma experience
4. Perceived social support
Neuroendocrinology of PTSD
-Catecholamines
-Glucocorticoids
Catecholamines
-abnormal urinary NE, EPI
-Downregulation of Alpha-adrenergic receptors
-Yohimbine can trigger flashbacks and panic attacks

Glucocorticoids
-Dexamethasone hypersuppression
-Decreased?? 24 hr cortisol secretion
--->rapid response and shutoff
Neurophsyiology of PTSD
-Psychophysiology
-Event related potentials
Psychophysiology
-hyper-responsiveness and decreased habituation

Event related potentials
-impaired attention and stimulus discrimination
Neuroanatomy of PTSD
-Imaging
-Biological model
Imaging
-smaller hippocampal volume

Model
-Event normally dually triggers amygdala (emotion) and hippocampus (context)
-High cortisol levels thought to inhibit hippocampal pathways