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67 Cards in this Set

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Purpose of having folded pattern of cortex?
allows for an increase in the SA of the cortical gray matter without a corresponding increase in size of the cranial vault
Compare
Gyrus
Sulcus
Fissure
Gyrus - elevation on surface of hemisphere
Sulcus - depression or groove between gyri
Fissure - a large and constant sulcus may be called a fissure, but the 2 terms are sometimes used interchangeably
In which fissure can you visualize the insula?
opening lateral fissure
What are the boundaries of the frontal lobe?
On lateral surface:
posterior boundary: central sulcus
Inferior boundary: lateral sulcus

On medial surface:
posterior: arbitrary line from central sulcus to CC
inferior: CC/cingulate gyrus (limbic lobe)
What are the boundaries of the parietal lobe?
on lateral surface:
anterior: central sulcus
interior: lat sulcus and an arbitrary line directed posteriorly from the lateral sulcus
Posterior: upper half of an arbitrary line connecting parieto-occiptal sulcus with the pre-occipital notch

Medial surface:
Anterior: frontal lobe
Posteror/inferior: parieto-occipitosulcus and cingulate gyrus
What are the boundaries of the temporal lobe?
on lateral surface:
superior: lateral sulcus and it posterior projection
posterior: lower portion of arbitrary line connecting the parieto-occital sulcus and the pre-occipital notch

on medial surface:
imaginary line joining the parieto-occipital sulcus and the pre-occipital notch
What are the boundaries of the occiptal lobe?
lateral surface: line joining the parieto-occipital sulcus to the pre-occiptal notch

medial: posterior borders of the parietal and temporal lobes
4 functional groups of the cortex?
Motor areas
Sensory areas
Language areas
Frontal association areas
General role of association areas of the cortex
produce a meaningful perceptual experience of the world, enable us to interact effectively, and support abstract thinking and language.
Components of the primary motor cortex
Precentral gyrus
Bordered by: Precentral sulcus + Central sulcus
Consequence of lesion to primary motor area
UMN signs
Location of the premotor or motor association areas
includes:
anterior part of precentral gyrus
parts of sup, middle and inf frontal gyri
Consequences of a lesion to the premotor or motor association area
Apraxia = deficits in learned, skilled motor activity, in absence of paralysis.
Location of primary somatosensory area
postcentral gyrus
Consequence of lesion to primary somatosensory area
- decreased awareness of sensory info
- reduced proprioception, touch and pain sensation
Location of the somatosensory association area
superior parietal lobules, extending onto medial surface
Consequence of lesion to somatosensory association area
Tactile agnosia = Impaired ability to recognize or identify objects by touch alone.
Location of the primary auditory area
superior surface of superior temporal gyrus - Heschl's gyri (aka transverse temporal gyri)
Consequences of a lesions to primary auditory area
- subtle impairment in hearing
- cannot localize sounds
- usually okay because bilateral input
Location of auditory association area
superficial temporal gyrus and area posterior to primary auditory area in lateral sulcus
Consequences of a lesions to auditory association area
Deficit in sound interpretation (even though can hear normally)
Location of primary visual area
in walls of posterior part of calcarine sulcus, extending onto lateral surface
Consequences of lesion to primary visual area
blindness in opposite visual field
Location of visual association area
surround primary visual are on medial and lateral surfaces
Consequences of lesion to visual association area
- Visual agnosia = unable to recognize object in opposite visual field, despite intact vision
- also, deficit in pursuit or tracking in IPSILATERAL eye
Location of the primary taste area
- on insula and adjacent medial surface of parietal-frontal operculum at base of centra sulcus (operculum = lid or cover, overlying cortical area)
- can be visualized deep in lateral fissure btw temporal and frontal lobes
Location of secondary taste area
orbital cortex of frontal lobe and amygdala
Function of secondary taste area
taste information is integrated with olfactory information
Functions of frontal association areas
aka prefrontal cortex
- concerned with complex aspects of behaviour (ie affect, personality, attention)
- extensive connection with dorsomedial (DM) nucleus of thalamus
Consequences of lesion to frontal association cortex
- change in emotion, motivation, personality, initiative, judgement, conentration, social behaviour, carelessness of appearance/dress
Location of motor speech area of broca
part of inferior frontal gyrus of dominant hemisphere (usually left)

* upside down U shape near intersection of premotor area and lateral sulcus
Function of broca's area
expression of speech
Consequences of lesion to broca's area
Nonfluent aphasia:
- cannot get words out properly even though normal comprehension
- aware of problem
Location of sensory speech are of Wernicke
- posterior part of the superior temporal gyrus, with extensions around the posterior end of the lateral sulcus into the parietal region (DOMINANT hemisphere - usually in left)

* armpit of lateral fissure
Function of wernicke's area
reception of speech (comprehension)
Consequences of lesion to wernicke's area
Fluent aphasia
speech fluent but nonsensical
- usually unaware of the problem
Consequence of lesion to language are of NON dominant hemisphere
Aprosodia
= deficit in intonative, rhythm
Types of association fibers
Short: connect cortical areas in adjacent gyri
Long: pass bw cortical areas that are further removed from each other
Superior longitudinal fasciculus
aka arcuate fasciculus (because arches over lateral fissure)
- located above the insula
- connects: frontal <-> parietal <-> temporal lobes
- connects wernickes and broca's areas
Consequence of lesion to arcuate fasciculus to speech
Conduction aphasia
Speech fluent but paraphasia word substitutions
errors (ex treen instead of train)

* due to sensory from broca not being properly passed to broca
Inferior occipitofrontal fasciculus
- runs below insula
- connects: frontal <-> temporal <-> occipital lobes
Unicate fasciculus
- part of inferior occipitofrontal fasciculus
- connect frontal and temporal lobe
Superior occipitofrontal fasciculus
- fibers fun adjacent and perpendicular to corpus collosum along most of its course
- connect: occipital and frontal lobes
Cingulum
- runs beneath cingulate gyrus and parahippocampal gyrus
- connects areas of limbic cortex with each other`
Commisural fibers
- connect R and L hemispheres
- largest one: corpus collosum
Connections made with body of CC
parietal lobes
posterior part of 2 frontal lobes
Connections made with splenium of CC
connects occipital lobes
posterior temporal lobes
Connections made with genu of CC
fibers originating in or proceeding to frontal areas
Connections made with rostrum of CC
thin shelf of fibers projecting backwards in genu
Connection made within radiations of CC
fibers fan out as they project to all parts of cortex
forceps minor : at anterior end
foreceps major : at posterior end
Anterior commissure
connects:
two anterior temporal lobes and
olfactory bulbs
Posteior commissure
connects the two pretectal nuclei
Projection fibers
thalamus <-> cortex
descending fibers to: striatum, brainstem and spinal cord
Internal capsule
compact bundle formed from gathering of projection fibers
Limbs of internal capule
anterior limb: cuts bw head of caudate and lenticular nucleus

posterior limb: cuts bw thalamus and lenticular nucleus

Genu = where two limbs meet
What is the lenticulate nucleus?
= putamen + globus pallacius
Location of basal nuclei and thalamus in relation to internal capsule
- caudate nucl. and thalamus always medial

- palladium and putamen always lateral
What type of information is processed by the thalamus?
What type of information is processed by the thalamus?
- all sensory information (except olfaction)
- basal ganglia
- cerebellum
- all sensory information (except olfaction)
- basal ganglia
- cerebellum
Major sensory relay nuclei of the thalamus + functions
- Ventral posterior (VPL, VPM) = somatosensory
- Medial geniculate nucleus (MGN) = hearing
- Lateral geniculate nucleus ( LGN) - vision
Major motor nuclei of the thalamus and their functions
- ventral lateral (VL)
- Ventral anterior (VA)

* connect with basal ganglia and cerebellum
Thalamic Limbic nuclei ?
Limbic nuclei in anterior thalamus connects with cingulate gyrus
MCA supplies..
most of lateral surface of the brain
ACA supplies..
medial surface of frontal and parietal lobes

* overlap onto lateral surface and supply thin border of the cortex
PCA supplies...
medial surface of temporal and occipital lobes

* overlap onto lateral surface and supply thin border of the cortex
Which vessels in brain are particularly susceptible to high BP?
- inferior choroidal aa.
- deep penetrating arteries of the MCA
What provides most blood supply to uncus?
Anterior choroidal arteries ( typically off int. carotid but sometimes arise from MCA)
What supplies internal capsule and basal ganglia?
Lenticulostriate arteries ( medial off ACA or lateral off MCA)