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38 Cards in this Set
- Front
- Back
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Person: discovered Bombay Phenotype in 1952 |
Bhende
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Bombay Phenotype: mode of inheritance
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Recessive
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Bombay Phenotype: All antigens are [absent/present]
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absent
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Bombay Phenotype: All antibodies are [absent/present]
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present
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Bombay Phenotype: phenotype with forward grouping
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Group O
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What are the two kinds of anti-H?
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Produced by Bombay; Produced as cold agglutinins
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Anti-H produced by Bombay: class of immunoglobulin
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IgM
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Anti-H produced by Bombay: reacts best at which temperature
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37 degrees Celsius
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Anti-H produced as cold agglutinins: most frequently subgroup of [..]
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A1
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Anti-H produced as cold agglutinins: reacts best at which temperature
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Room Temp
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Order of reactivity with anti-H
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O > A2 > B > A2B > A1 > A1B
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Three classifications of Bombay
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RBC H deficient/non-secretor
RBC H partially deficient/non-secretor RBC H deficient/secretor |
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Substances weakly expressed in secretions of RBC H deficient/secretor bombay type
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ABH substances
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Which typing isn't done for newborns?
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Backward typing
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Disease: depressed ABH antigens; mixed field agglutination microscopically
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Hodgkins disease
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Example of hemolytic disease that induces stress hematopoiesis
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Thalasesemia
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error that can be resolved by repeating the test
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Technical error
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Resistance to transfusion
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Refractoriness
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ABO Discrepancy: In case of missing/weak Abs, do not perform which kind of typing?
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Backward
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ABO Discrepancy: Pxs with leukemia/lymphoma/immunosuppressive drugs have missing/weak Abs due to [..]
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hypogammaglobulinemia
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ABO Discrepancy: Px with immunodeficiency disease have missing/weak [Abs/Ags]
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Abs
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ABO Discrepancy: Px with congenital agammaglobulinemia have missing/weak [Abs/Ags]
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Abs
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Presence of two cellular populations in a single individual
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Chimerism
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Chimerism can be solved by [..]
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incubating serum for 15-30 minutes
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ABO Discrepancy: In case of missing/weak Ags, do not perform which typing
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Forward typing
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Spontaneous red cell agglutination iwth all sera, regardless of blood type
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Polyagglutination
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Polyagglutination: caused by the action of uraminidase
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T poly
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Polyagglutination: only temporary
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T poly
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Polyagglutination: cryptic antigen
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T poly
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Polyagglutination: caused by a mutation in the hematopoeitic tissue
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Tn poly
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Polyagglutination: caused by insufficient addition of sialic acid during RBC maturation
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Tn poly
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Associated with asepticemia infection by P. mirabilis
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Tn poly
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Polyagglutination: carry large amounts of Sda antigen
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Cad poly
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Polyagglutination: associated with P. falciparum
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Cad poly
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Protein/plasma abn: discrepancy in [...] typing
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backward
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Associated with septicemic infection caused by Proteus vulgaris
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Acquired B phenomenon
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Excess amount of BGSSS phenotypes as [..]
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Type O |
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Acquired B phenomenon phenotypes as [..]
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Type AB |
