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33 Cards in this Set

  • Front
  • Back
How many spinal cord segments are there?
31
What are the different sections of the spinal cord?
Cervical (C1-C8)

Thoracic (T1-T12)

Lumbar (L1-L5)

Sacral (S1-S5)

Plus 1 coccygeal segment
What is an easy way to tell the difference between dorsal and ventral spinal cord?
Ventral has a larger separation (fissure) between left and right ventral white matter
What are the 2 types of matter in the spinal cord?

What makes them up?
White matter: Mylinated fiber (axon) tracts

Grey matter: Neuronal cell bodies/small processes
The dorsal cord carries and processes what type of information?
Sensory information
The intermediate zone (sensorimotor) does what?
Integrates sensory information and directs motor output
The ventral cord contain what?
Contains motor neurons
What do afferent and efferent apply to in terms of sensory and motor?
Afferent: Sensory. Signaling coming into the CNS.

Efferent: Motor. Signals taking information out of CNS to muscles
The dorsal columns carry exclusively what information?
Ascending sensory information
The ventral columns carry primarily what?
Descending motor commands
The lateral columns in the SC contain what?
A mixture of ascending sensory and descending motor pathways
Where are all the sensory neuron cell bodies located?
OUTSIDE the CNS in the Dorsal Root Ganglion
Sensory neurons are classified on the basis of what?
Their Axon Diameters
Group I axons contain what neurons?
Largest diameter, fastest conducting axons: Muscle Sensory Neurons
Group III/IV axons contain what neurons?
Sensory neurons for pain/temp

Recall: Do not use the dorsal columns, but rather comprise anterolateral system
What are the 2 types of motor neurons?
1. Alpha motor neurons

2. Gamma motor neurons
What is the function of an alpha motor neuron?
- Large Diameter

- Make excitatory synapses on skeletal muscle fibers and directly control skeletal muscle contraction
What is the function of a gamma motor neuron?
Small Diameter

- Synapse on specialized, small muscle fibers withing sensory structures called muscle spindles

- Controls spindle SENSITIVITY
What are the 2 muscle sensory receptors?

Their Functions?
1. Muscle Spindles - sense STRETCH of muscles

2. Golgi Tendon Organs - sense CONTRACTION of muscles
Where are muscle spindles and golgi tendon organs found?
Muscle spindles - found throughout the muscle. Set up in parallel with extrafusal fibers (so they experience same length changes)

Golgi Tendon Organs - Located at tip of each muscle at muscle-tendon junction
Muscle spindles are innervated by what 2 types of sensory neurons?
1. a single group Ia sensory neuron

2. A single group II sensory neuron
Where are intrafusal fibers contractile?
Only at their tips
How do the sensory neurons detect stretch within the muscle spindle?
Local membrane stretch activates stretch-sensitive ion channels in the sensory neurons, causing a depolarization
Golgi Tendon Organs are innervated by what?
Dendrites of a single group of Ib Afferent neurons
What provides compensatory regulator of spindle sensitivity?
Gamma motor neurons
What is the purpose of alpha/gamma MN co activation?
Enables the spindles to remain stretch sensitive regardless of the amount of contraction in the parent muscle
What is reciprocal innervation?
Common theme in spinal reflexes where sensory input will excite MN's that innervate a particular muscle and inhibit MN's that innervate the antagonist
What is the simplest and fastest somatic reflex?

Why?
Myotactic (stretch) reflex

Because Only reflex involving just one synapse within the SC and associated sensory/motor neurons are both the largest diameter
What is the function of the Golgi Tendon Organ reflex?
Opposes excessive contraction of the muscle in which it is located
Does the GTO reflex contain interneurons?
YES, has interneurons for both extensor (inhibitory) and flexor (excitatory) muscles
What are the 2 movement components of the withdrawal reflex?
1. Ipsilateral Flexion

2. Contralateral Extension
What is the effect of stimulus strength on the withdrawal reflex?
The stronger (more painful) the stimulus, the larger number of sensory neurons activated.

Strengthens reflex and EXTENDS the reflex circuit action to additional SC segments, recruiting other parts of the body.
Are reflex responses static?
NO, extensively regulated by descending projections and local spinal cord circuits.