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19 Cards in this Set

  • Front
  • Back
which cytokines are involved in the activation of endothelial cells (inflammation, coagulation)?
TNF and IL-1
which cytokines act on the hypothalamus and cause fever?
TNF and IL-1
which cytokines stimulate the synthesis of acute phase proteins in the liver?
TNF, IL-1, IL-6
which cytokine stimulates the catabolism of muscle and fat (cachexia)?
TNF
which cytokines activate leukocytes and cause increased integrin affinity?
chemokines
which cytokine causes TH1 differentiation?
IL-12
which cytokines are anti-viral?
type I IFNs
which cytokine inhibits IL-12 production and reduces expression of costimulators and class II MHC molecules?
IL-10
which cytokine causes proliferation of antibody-producing cells?
IL-6
which cytokines increase IFN-γ production?
IL-12 and IL-18
which cytokine is responsible for survival, proliferation, and differentiation of effector and regulatory T cells?
IL-2
which cytokine causes B cells to switch to IgE?
IL-4
which cytokine activates eosinophils?
IL-5
which cytokine inhibits T cell activation?
TGF-β
which cytokine causes differentiation of regulatory T cells?
TGF-β
which cells contain IL-2?
CD4+ and CD8+ T cells
which cells contain IL-4?
CD4+ T cells and mast cells
which cells contain IL-5?
CD4+ T cells and mast cells
which cells contain TGF-β?
CD4+ T cells and many other cell types