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19 Cards in this Set
- Front
- Back
which cytokines are involved in the activation of endothelial cells (inflammation, coagulation)?
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TNF and IL-1
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which cytokines act on the hypothalamus and cause fever?
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TNF and IL-1
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which cytokines stimulate the synthesis of acute phase proteins in the liver?
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TNF, IL-1, IL-6
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which cytokine stimulates the catabolism of muscle and fat (cachexia)?
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TNF
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which cytokines activate leukocytes and cause increased integrin affinity?
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chemokines
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which cytokine causes TH1 differentiation?
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IL-12
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which cytokines are anti-viral?
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type I IFNs
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which cytokine inhibits IL-12 production and reduces expression of costimulators and class II MHC molecules?
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IL-10
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which cytokine causes proliferation of antibody-producing cells?
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IL-6
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which cytokines increase IFN-γ production?
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IL-12 and IL-18
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which cytokine is responsible for survival, proliferation, and differentiation of effector and regulatory T cells?
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IL-2
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which cytokine causes B cells to switch to IgE?
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IL-4
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which cytokine activates eosinophils?
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IL-5
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which cytokine inhibits T cell activation?
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TGF-β
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which cytokine causes differentiation of regulatory T cells?
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TGF-β
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which cells contain IL-2?
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CD4+ and CD8+ T cells
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which cells contain IL-4?
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CD4+ T cells and mast cells
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which cells contain IL-5?
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CD4+ T cells and mast cells
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which cells contain TGF-β?
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CD4+ T cells and many other cell types
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