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25 Cards in this Set

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Name critical structures in the extrapyramidal system?
Basal Ganglia:
Caudate,
Putamen,
Globus Pallidus,
STN
Substantia Nigra
http://www.dartmouth.edu/~dons/part_3/chapter_26.html
The basal ganglia plays an important role in:
--Initiation and maintenance of movement
--Postural control
--Resting muscle tone
--Automatic associated movements (arm swing)
--Possibly emotional expression (smiling, frowning, laughing, crying)
http://www.dartmouth.edu/~dons/part_3/chapter_26.html
The caudate and putamen are separated in some places by:
Penetrating fibers of the Internal Capsule...

But remain joined in other places by cellular bridges.
Blumenfeld
Describe the Internal Capsule
A V-shaped collection of fibers going to and from the cortex.

The Corticobulbar and Corticospinal tracts lie in its posterior limb.
Blumenfeld
The caudate and putamen comprise the:
Striatum (or neostriatum)
Blumenfeld
What receives all inputs to the basal ganglia?
Striatum (caudate and putamen)
Blumenfeld
True or False

The caudate and thalamus are always medial to the internal capsule.
True
Blumenfeld
The lentiform nucleus is comprised of the:

And is situated:
Putamen and globus pallidus.

Lateral to the internal capsule
Blumenfeld
What form the lateral walls of the 3rd ventricle.
Thalaums
Blumenfeld
The head and body of the caudate form a bulge on:
The lateral wall of the lateral ventricle.
Blumenfeld
Basal ganglia lesions can lead to what types of motor symptoms?
Dystonia
Rigidity
Myoclonus
Tremor
Bradykinesia, Hypokinesia, & Akinesia
Dyskinesia (Chorea, Athetosis)
Tremor
Abulia
True or False
The basal ganglia are part of a network of complex loops that exert their major influence on descending motor systems through projections to the motor and premotor cortex.
True
Blumenfeld
Types of Tremors:
Resting
Postural (Essential is most typical)
Intention (Ataxic)
Essential tremor
Usually involves hands or arms but can affect jaw, tongue lips, head, vocal cords, legs or trunk.
Can result in difficulty holding a glass without spilling, writing, etc.
ie: Katherine Hepburn
Intention tremor
Usually cerebellar.

Occurs as patient tries to move limb toward target.
What degenerates in Huntington's?
Striatal neurons in the caudate and putamen
Blumenfeld
What basal ganglia structures lie behind the internal capsule.
Caudate and Thalamus
The tail of the caudate lies where?
It runs along the roof of the temporal horn
Outputs leave the basal ganglia via the:
Internal segment of the globus pallidus (GPi) &

Substantia Nigra pars reticulata (SNr)
True or False:

Spasticity and Ataxia are basal ganglia disorders.
False.
Spacticity is due to corticospinal UMN lesions;

Ataxia is due to lesions of cerebellar circuitry.
Paratonia is:

And is seen in patients with:
Involuntary "activel" resistance during passive movement of their limbs. Unlike Parkinson's rigidity, it has an inconsistent, almost voluntary quality.

Frontal lobe dysfunction
List causes of increased tone.

Localize each.
Spacticity: Corticospinal tract
Rigidity: Basal Ganglia
Dystonia: Basal Ganglia
Paratonia: Frontal lobe dysfx
Wilson's Disease is characterized by:
Gradual onset of:
Dysarthria
Dystonia (some with facial dystonia causing wry smile)
Rigidity
Tremor (some with wind-beating tremor)
Choreoathetosis
Prominent psyc disturbance
Kayser-Fleischer rings (copper).

An autosomal recessive disorder of biliary copper excretion
Is apraxia cortical or subcortical?
Cortical
True or False

The basal ganglia is involved in general motor fxs, eye movements, frontal executive fx, and limbic pathways.
True