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14 Cards in this Set
- Front
- Back
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What is the most common form of skin cancer
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Basal cell carcinoma
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Basal cell carcinoma occurs in sun exposed skin
T/F |
Generally true, but may also occur in sun protected skin.
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What skin exposures increases risk for BCC?
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Chronic venous stasis, AV malformations, arsenic ingestion, x-ray exposure, skin injury, chickenpox scar, tattoos, hair transplant scars, immune suppression.
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What is the clinical appearance of BCC?
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Variable, could be nodular, ulcerative, superficial, erythmatous, sclerosing, keloidal.
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Arises on the trunk, flat and erythmatous, grows in lateral direction.
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Superficial basal cell carcinoma
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Contains atypical squamous cells, more agressive than conventional basal cell.
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Basosquamous
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Contains tumor cells with cytoplasmic granules like granular cell tumor of the dermis and other locations.
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Granular cell basal cell carcinoma
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Contains tumor cells with prominent cytoplasmic vacuoles and signet ring configuration
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Clear cell basal cell carcinoma
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Has evidence of hair follicle differentiation
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Infundibulocytic basal cell carcinoma
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Often occurs on back, traditionally regarded as a polypoid variant.
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Fibroepithelial tumor
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Characterized by areas of basal cell carcinoma with admixed bone formation.
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Sarcomatoid basal cell carcinoma.
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More than 80% of BCC overexpress the __ protein.
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p53
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BCC is usually (-/+) for EMA, CEA, and involucrin.
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Negative
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Positive immuno markers of BCC include
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CD10, Ber-EP4.
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