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8 Cards in this Set
- Front
- Back
tetracyclines
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oral, topical
inhibit RNA to mRNA AE: teeth discolored, photosensitive CI: pregnant/breast feeding -empty stomach -with short and intermediate acting agents *space 2 hrs from Ca, Fe, and Mg foods (diary, laxatives, antacids...) |
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doxycycline
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r/t tetracycline
lyme disease longer life, better absorbed |
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Macrolide antibiotics
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erthromycin, Z Pack
G+, pastroparesis IV, oral, topical *SAFE w/ PCN allergy AE: p. colitis, cholestatic hepatitis, prolonged QT |
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Lincosamides
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(clindamycin)
aerobic G+ cocci or anerobic G+/G- OUT of CNS AE: p. colitis *teach: contraceptive Ix, diarrhea |
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Chloramphenicol
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broad spec
AE: bone marrow tox, optic neuritis, periph. neur. *gray-baby syndrome |
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oxazolidinones
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(linezolid)
for MRSA & VRE - need ID approval blocks early stg so resistance cant form easy. AE: bone marrow supp, p. colitis Ix: MAOI, sympathmimetics hyperTN crisis: SSRIs, meperidine |
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streptogramins
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(-pristins)
VRE - ID approval req'd caution w/ liver pts (water LFTs) X saline or heparin - flush w/ d5w!!! |
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bacteriostatic drugs
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tetracyclines
macrolides licosamides chloramphenicol oxazolidinones streptogramins |