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107 Cards in this Set

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Can you vaccinate neonatal animals against E.coli?
No, don't mount immune animals
Treatment for E.coli
* fluid & electrolytes
* antibiotics should not be used indiscriminately b/c salmonella can take over if natural flora killed off
*vaccines can be used to treat endotoxemia
* antibiotics given IV to treat septicemia
Are there good vaccines for Salmonella ?
No, cannot vaccinate animal that are carrier - also intracellular agent so difficult to detect
What zoonotic bacteria spread from cats, rats, (endemic to certain parts of usa wild animals have it and can ingest or flea bites)?
Yersinia pestis <- causes plague
What antibiotic effective for Yersinia?
tetracycline
T/F Shigella infects cattle, pigs, horses, etc.
False; Shigella
pathogen to humans/primates, can infect dogs but don’t show disease, does NOT infect cattle, pigs, horses, etc.
T/F Penicillin is effective against Enterobacteriaceae
False
T/F Salmonella can cause enteritis and septicemia; septicemia in pregnant animals may lead to abortion
True; esp. associated pigs
T/F Salmonella, Clostridrium, Escherichia coli, and Klebsiella are all in Enterobacteriaceae family.

T/F Enterobacteriaceae are gram positive cocci and facultative anarobes
False; Clostridrium is NOT; others are

False; Enterobacteriaceae are gram negative rods and facultative anarobes, can survive in either environment
How do you discriminate between E.coli and Salmonella?
* E.coli can ferment lactose on MaConkey agar
saprophytic (in decaying material) bacteria, found in mucous membranes, skin, opportunistic organism i.e. in wound infections
Pseudomonas

opportunistic, not usually cause of major outbreaks, causes sporodic disease, immunodef. more susceptible
e.g. burn infection, otitis externa in dogs
T/F Pseudomonas causes septicimeia, abortion, diarrhea in cattle?
False
What disease is Pseudomonas associated with in pigs?

What disease is Pseudomonas associated with in sheep?
often carriers


Fleece rot
What disease is Pseudomonas associated with in mares?
Genital tract infection, Ulcerative keratitis
Treatment for Pseudomonas ?
often drug RESISTANT, need to do sensitivity test

penicillin= NO; gentamicin <-YES. can also use amikacin; or polymyxin for topical use
Pseudomonas aeruginosa can cause Hemorrhagic pneumonia in ___ frothy bloody discharge from nose
in mink
Burkholderia mallei causes ?

endemic to where?
Burkholderia mallei causes 'Glanders'

exotic disease, endemic to Africa and mideast
Diagnosis of Glanders?
Mallein test - interpalpebral test for DTH

- look for drooping of lower eyelid

"mallein" is extract from
Burkholderia mallei
Treatment for Glanders?
* don't use antibiotic, NOT permitted
* became carrier, spread to other animals
* cannot remove completely
* cull infected animals?
lumpy jaw which is caused by ?
- Actinobacillus bovis
Actinob. equuli causes ?

Explain pathogenesis:
A. equuii : causes SLEEPY FOAL disease
- commensal of intestine, if immunosuppressed causes septicemia (animal become dull, sleepy) and infect kidney
Actinobacillus suis causes :
Actinobacillus suis
* causes septicemia, pneumonia, meningitis in pigs
* commensal of pig farms
Actinobacillus suis antibiotic?
Treat with ampicillin or TMS
Past. multocida causes disease in?

Hint: PMS
* associated w/dogs and cats in mouth
(not large animals)
* enter via cut in mouth
* rabbits (Hint: P. Multicida Snuffles)
* birds
Produces a leukotoxin, so vaccines are made with a leukotoxin Ag
Mannheimia haemolytica:
Mannheimia haemolytica do NOT infect ?
does not infect cats, dogs, pigs, etc.

only ruminants
- Mannheimia haemolytica causes ____ in cattle

o ___ in sheep and goats
SHIPPING FEVER in cattle

Mastitis (“BLUE BAG”) in sheep and goats
~ endotoxin cause bluish discoloration of mammary gland
Are vaccines available in US for shipping fever in cattle?
If so, what do they protect against?
Yes, protect cattle against leukotoxin of Manheimia haemolytica
Causes snuffels in rabbits?
Past. multocida
Francisella tularensis causes what zoonotic diseases?

How transmitted?
Tularemia

cats and dogs can get from rodents, ticks
* Humans get it from tick bites and handling contaminated meat
Tularemia caused by francisella tularensis in endemic to
USA
- Actinobacillus pleuropneumonia, used to be part of Haemophilus genus, causes ____ of swine
o causes CONTAGIOUS PLEUROPNEUMONIA of swine
Do antibiotic completely remove Actinobacillus pleuropneumonia pathogen?
If the animal survives infection, they become a ____
o Antibiotics only reduce the symptoms, they do not get rid of the abscesses in the lungs and the organism survives in them and the pigs act as carriers
Associated GLASSER’S DISEASE in pigs
- Haemophilus parasuis -> GLASSER’S DISEASE

HP great desktops
- Haemophilus parasuis causes
GLASSER'S disease
* septicemia in pigs
* pneumonia in pigs
* characterized by polyserositis in the pleuro and peritoneal cavity
What pathogen transmitted venereally, males can carry the bacterium and transmit infection to females?
- Histophilus somni
- Taylorella equigenitalis
What pathogens can causes abortion? (4)
histophilus somni, salmonella, brucella, leptospira

e.g. salmonella typhimurium -> cattle and pigs

- Taylorella equigenitalis rarely causes abortion
Histophilus somni causes ?
1. infection of genital tract
OR
2. - causes ITEME (infectious thromboembolic meningoencephalitis)
- can multiply in brain
- animals look dull and sleepy
- can cause pneumonic infection
- can also cause pericardial abscesses
- Taylorella equigenitalis causes ?

Are serlogical tests available?
Taylorella equigenitalis causes Contagious Equine Metritis (CEM), animal becomes sterile
- exotic disease, UK, ireland, etc.
- eradicated in US

NO sero.tests
o What causes 1. KENNEL COUGH in dogs, 2. feline bronchopneumonia in cats,
3. causes ATROPHIC RHINITIS in pigs?
Bordetella bronchiseptica
- Moraxella bovis causes ?
Moraxella bovis: causes Infectious Bovine Kerato-Conjunctivitis (IBKC) or “Pink eye” in cattle
* has pilli and attaches to cornea and produced enzymes which damage cornea, cause opacity of cornea and blindness
Moraxella bovis treatment?
antibiotics?
vaccines?
* penicillin locally
* tetracycline (oxytetracycline) parenteral
o Pilus vaccine available
o Treatable in early stages
o Flies may transmit infection, use fly repellant tags
o Keep animals away from sunlight
- Intracellular bacterium
- DOES NOT KILL ANIMALS
- Causes ABORTION
- genital disease, predilection site is uterus and male genital tract
Brucella (B. abortus)
Brucella causes
Brucella causes: endometritis, placentitis, semen abnormalities
Are there vaccines for treating brucella?
Live vaccine available, doesn’t work well at all; can infect humans (old, live vaccine)
Brucella intracellular bacterium, but can it survive in external environment for long time?
yes, for approx. 6 months
Is brucella a saprophyte?
No
Is brucella communicable to humans?
- All form of Brucella are communicable to humans EXCEPT B. bovis

(B.canis, B.suis, B.abortus, etc are zoonotic)
Antibiotics for food producing animals with brucella?
Do not use antibiotics in Brucella infected food producing animals
- Gram neg curve bacteria (3)
Campylobacter, Lawsonia intercellaris, Helicobacter
Campy. jejuni causes ?


can it cause abortion?
o Causes diarrhea in humans, dogs and cats
o Abortion rarely
Lawsonia intercellaris causes? in ?
- Causes Porcine intestinal adenomastosis (PIA) in pigs
- Thickening of intestine, animal will have chronic diarrhea
like “garden hose”
Treatment for Lawsonia intercellaris?
- No vaccines
- Treat with tylosin (macrolide-class antibiotic)
NAME spiral bacteria belonging to spirochete group, any spirals unlike camphylobacter (curvy)
- Has several serotypes
- Predilection site is kidney!!!!!!!!!!
Excreted in URINE – contaminates water sources and humans and animals can get infections by drinking contaminated water
Leptospira
Carriers of leptospira?
rodents
Leptospira infectious to dogs and cats?

Zoonotic?
No, cats can't get leptospira..can eat as many dead rats as they want

Yes, zoonotic
- L. icterrohaemorrhagiae is associated with dogs; what condition?
L. icterrohaemorrhagiae (dogs) -> jaundice
What STRAINS of leptospira associated with dogs? (2)
L. canicola
L. icterrohaemorrhagiae (can be fatal i think)
Treatment for Leptospira?
Are vaccine available?
Be specific why, why not
Good vaccines available
- There are vaccines for dogs – outer sheath protein Ag
- Tx: penicillin, streptomycin, tetracyclines, DOXYCYCLINE for dogs
Brachyspira
- B. hyodysenteriae
Causes?
Treatment?
Vaccine?
* Causes swine dysentery
o Gram stain: fecal material, spiral bacteria seem
o Culture on special BA (anaerobic)
o No vaccines (intracellular?)
o Tx: tylosin (spirocete = tylosin)
o Disinfect area and keep animals off for 2 months
Leptospira can cause meningitis in humans?
True
Brachyspira hyodysenteriae causes?
in ?
aerobic?
carriers?
Brachyspira hyodysenteriae causes: swine dysentery

anaerobic, O2 tolerant
Disease limited to intestine
Carrier pigs (rats, mice temporary)
Treatment for brachyspira hyodysenteriae ?

Hint: what's good antibiotic for curvy & spirocetes?
* Antibiotics (e.g. Tylosin) in feed for prevention and treatment effective
* Sanitation/ disinfection concurrently Rest for 60 days (organism dies off)
* Replacement pigs – from known source Quarantine and medication
How to culture - B. hyodysenteriae?
Culture on special BA (anaerobic)
Swine dysentery: Clinical signs
Swine dysentery: Clinical signs, lesions (hemorrhagic colitis)
Borrelia: B. burgdorferi causes?
LYME DISEASE
Treatment for lyme disease?
Treatment/ control: doxycycline (tetracycline) or other antibiotics 4 weeks
Vaccine (outer sheath antigen – ospA), tick control
What do all have in common?
Fusobacterium
Mycoplasma
Chlamydiae
Ehrlichia
Rickettsia
Non spore-forming anaerobes
Fusobacterium
Mycoplasma
Chlamydiae
Ehrlichia
Rickettsia
causes calf dyptheria
- Fusobacterium necrophorum

Two forms of calf diphtheria. Most common is acute oral (mouth) infection, seen in calves less than 3 mo. old. Second form is seen in older calves and affects the larynx, Both caused by Fusobacterium necrophorum, which also causes foul-in-the foot and liver abscesses in older cattle.
- Causes contagious bovine pleuropneumonia (CBPP) in cattle
Mycoplasma mycoides
- No cell wall
- anarobe, non spore forming
Is contagious bovine pleuropneumonia (CBPP) in cattle fatal?

What causes it?
Yes

Mycoplasma mycoides causes contagious bovine pleuropneumonia (CBPP)
Can you culture Mycoplasma on Mac or BA?

Are vaccine available for Mycoplasma? Antibiotics?
No, can't culture this way, they need a soft agar media with 20% serum

No, vaccine not available, and antibiotics may creat carrier state in CBPP; test and slaughter policy practiced
-> with less contagious Mycoplasma diseases, tylosin a/o tetracycline are effective
Can mycoplasma mycoides kill dogs in large numbers?
No
Is mycoplasma mycoides endemic to US or exotic disease?
exotic dz
Mycop. gallisepticum causes ?
M. gallisepticum
* causes chronic respiratory disease (CRD) in chickens
Mycop. felis causes ?
conjunctivitis in cats
Chlamydiae, Ehrlichia, Anaplasma, Rickettsia, Neorickettsia, Coxiella, Bartonella: all treated with ??
Clamydiae, Ehrlichia, Anaplasma, Rickettsia, Neorickettsia, Coxiella, Bartonella: all treated with TETRACYCLINE
Clamydiae, Ehrlichia, Anaplasma, Rickettsia, Neorickettsia, Coxiella all treated with ?
: all intracellular bacteria; treated with tetracycline
- Causes: TRACK FEVER in dogs and hemorrhagic fever
Ehrlichia canis:
Ehrlichia does not affect ??
Ehrlichia does not affect cats
___ causes ROCKY MOUNTAIN SPOTTED FEVER
Rickettsia
Rickettsia (RMSF) is disease in ?
Rickettsia in dogs and humans; does not affect cats
Neorickettsia causes ___ in ____
Neorickettsia causes salmon poisoning in dogs, not cats
Coxiella burneti causes ____ in _____

How transmitted?
Coxiella burneti causes Q FEVER in ruminants and humans
- can infect placenta, abortion, fluid infective e.g. milk, urine, feces
- zoonotic pathogen!
vector for ehrlichea?
ticks
causes "cat scratch disease"
bartonella
cause ovine foot rot
- Fusobacterium necrophorum + Dichelobacter nodosus
T/F Potomac Horse Fever (Neorickettsia/Ehrlichia) can cause abortion ?

T/F Potomac Horse Fever (Neorickettsia/Ehrlichia) not fatal
True

False, up to 30% cases are fatal
Anaplasma and Neorickettsia are treated with ?
oxytetracycline
Can cause mastitis in cattle? (5)
Streptococcus (3)
Actinomyces pyogenes
Enterobacteriaceae coli -> coliform
Klebsiella pneumoniae
Pseudomonas aeruginosa
Can cause UTI in dogs? (name 5)
Enterobacteriaceae coli
Klebsiella pneumoniae
Proteus mirabilis
Pseudomonas aeruginosa
Staphylococcus (3)
Is mycoplasma fatal in dogs?

Is mycoplasma fatal in cattle?
No, not usually

- M. mycoides fatal in cattle, but mild in dogs
Causes pneumonia in cattle?
Enterobacteriaceae coli -> cattle
Klebsiella pneumoniae -> cattle
Pasteurella multocida -> cattle
Pseudomonas aeruginosa -> dogs and cats, sheep, cattle
Can you use penicliin for mycoplasma infection?
Why?
No, have no cell wall
Where might one find mycoplasma infection?
Respiratory illnesses in ruminants (CBPP) and pigs
Also conjuctivitis in cats

MYCO MYC...Ck Bt Plw Pfr
Aside from Mycoplasma, what else could cause conjunctivitis in eye of cat?
What antibiotic could you use to treat both?
Chlamydia
Salmonella enterica causes disease in?

Salmonella dublin causes disease in?
not species specific; all animals

Dublin? in cattle, sheep, horses, dogs
Salmonella typhimurium causes disease in?

Salmonella typhi causes disease in?
many animals, humans included


humans
Salmonella cholerasuis causes disease in?
pigs
which salmonella serovar causes disease in chicks? in US?
Salmonella pullorum, called Pullorum disease; not common in US

Hint: both bird serovars end w/-rum
Which salmonella serovar causes disease in adult birds outside US?
What name of disease?
S. gallinarum, disease called Fowl typhoid; not common in US
Which pathogen causes typhoid in humans?
Salmonella typhi
Hemorrhagic Colitis is associated with what ?
Shiga toxin producing E.coli (STEC), a pathogenic strain
E.coli O157: K88 ; H2 (pig)
Pathogenic strains are classified by serotyping. What antigens are {O, K, H} associated with?
O: cell wall
K: capsule and pilli antigen
H: flagella
Which of following is not a "coliform"?
Klebsiella
E.coli
Salmonella
Streptococcus
Coliform bacteria are Gram-negative non-spore forming rods which can ferment lactose.
Therefore, Salmonella (NLF) and Strep (gr+) cannot be included
Can coliforms cause mastitis in cattle?
yes
Atrophic Rhinitis
Pasteurella multocida -> pigs