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107 Cards in this Set
- Front
- Back
Can you vaccinate neonatal animals against E.coli?
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No, don't mount immune animals
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Treatment for E.coli
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* fluid & electrolytes
* antibiotics should not be used indiscriminately b/c salmonella can take over if natural flora killed off *vaccines can be used to treat endotoxemia * antibiotics given IV to treat septicemia |
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Are there good vaccines for Salmonella ?
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No, cannot vaccinate animal that are carrier - also intracellular agent so difficult to detect
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What zoonotic bacteria spread from cats, rats, (endemic to certain parts of usa wild animals have it and can ingest or flea bites)?
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Yersinia pestis <- causes plague
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What antibiotic effective for Yersinia?
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tetracycline
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T/F Shigella infects cattle, pigs, horses, etc.
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False; Shigella
pathogen to humans/primates, can infect dogs but don’t show disease, does NOT infect cattle, pigs, horses, etc. |
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T/F Penicillin is effective against Enterobacteriaceae
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False
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T/F Salmonella can cause enteritis and septicemia; septicemia in pregnant animals may lead to abortion
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True; esp. associated pigs
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T/F Salmonella, Clostridrium, Escherichia coli, and Klebsiella are all in Enterobacteriaceae family.
T/F Enterobacteriaceae are gram positive cocci and facultative anarobes |
False; Clostridrium is NOT; others are
False; Enterobacteriaceae are gram negative rods and facultative anarobes, can survive in either environment |
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How do you discriminate between E.coli and Salmonella?
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* E.coli can ferment lactose on MaConkey agar
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saprophytic (in decaying material) bacteria, found in mucous membranes, skin, opportunistic organism i.e. in wound infections
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Pseudomonas
opportunistic, not usually cause of major outbreaks, causes sporodic disease, immunodef. more susceptible e.g. burn infection, otitis externa in dogs |
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T/F Pseudomonas causes septicimeia, abortion, diarrhea in cattle?
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False
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What disease is Pseudomonas associated with in pigs?
What disease is Pseudomonas associated with in sheep? |
often carriers
Fleece rot |
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What disease is Pseudomonas associated with in mares?
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Genital tract infection, Ulcerative keratitis
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Treatment for Pseudomonas ?
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often drug RESISTANT, need to do sensitivity test
penicillin= NO; gentamicin <-YES. can also use amikacin; or polymyxin for topical use |
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Pseudomonas aeruginosa can cause Hemorrhagic pneumonia in ___ frothy bloody discharge from nose
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in mink
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Burkholderia mallei causes ?
endemic to where? |
Burkholderia mallei causes 'Glanders'
exotic disease, endemic to Africa and mideast |
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Diagnosis of Glanders?
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Mallein test - interpalpebral test for DTH
- look for drooping of lower eyelid "mallein" is extract from Burkholderia mallei |
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Treatment for Glanders?
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* don't use antibiotic, NOT permitted
* became carrier, spread to other animals * cannot remove completely * cull infected animals? |
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lumpy jaw which is caused by ?
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- Actinobacillus bovis
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Actinob. equuli causes ?
Explain pathogenesis: |
A. equuii : causes SLEEPY FOAL disease
- commensal of intestine, if immunosuppressed causes septicemia (animal become dull, sleepy) and infect kidney |
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Actinobacillus suis causes :
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Actinobacillus suis
* causes septicemia, pneumonia, meningitis in pigs * commensal of pig farms |
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Actinobacillus suis antibiotic?
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Treat with ampicillin or TMS
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Past. multocida causes disease in?
Hint: PMS |
* associated w/dogs and cats in mouth
(not large animals) * enter via cut in mouth * rabbits (Hint: P. Multicida Snuffles) * birds |
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Produces a leukotoxin, so vaccines are made with a leukotoxin Ag
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Mannheimia haemolytica:
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Mannheimia haemolytica do NOT infect ?
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does not infect cats, dogs, pigs, etc.
only ruminants |
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- Mannheimia haemolytica causes ____ in cattle
o ___ in sheep and goats |
SHIPPING FEVER in cattle
Mastitis (“BLUE BAG”) in sheep and goats ~ endotoxin cause bluish discoloration of mammary gland |
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Are vaccines available in US for shipping fever in cattle?
If so, what do they protect against? |
Yes, protect cattle against leukotoxin of Manheimia haemolytica
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Causes snuffels in rabbits?
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Past. multocida
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Francisella tularensis causes what zoonotic diseases?
How transmitted? |
Tularemia
cats and dogs can get from rodents, ticks * Humans get it from tick bites and handling contaminated meat |
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Tularemia caused by francisella tularensis in endemic to
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USA
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- Actinobacillus pleuropneumonia, used to be part of Haemophilus genus, causes ____ of swine
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o causes CONTAGIOUS PLEUROPNEUMONIA of swine
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Do antibiotic completely remove Actinobacillus pleuropneumonia pathogen?
If the animal survives infection, they become a ____ |
o Antibiotics only reduce the symptoms, they do not get rid of the abscesses in the lungs and the organism survives in them and the pigs act as carriers
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Associated GLASSER’S DISEASE in pigs
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- Haemophilus parasuis -> GLASSER’S DISEASE
HP great desktops |
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- Haemophilus parasuis causes
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GLASSER'S disease
* septicemia in pigs * pneumonia in pigs * characterized by polyserositis in the pleuro and peritoneal cavity |
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What pathogen transmitted venereally, males can carry the bacterium and transmit infection to females?
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- Histophilus somni
- Taylorella equigenitalis |
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What pathogens can causes abortion? (4)
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histophilus somni, salmonella, brucella, leptospira
e.g. salmonella typhimurium -> cattle and pigs - Taylorella equigenitalis rarely causes abortion |
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Histophilus somni causes ?
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1. infection of genital tract
OR 2. - causes ITEME (infectious thromboembolic meningoencephalitis) - can multiply in brain - animals look dull and sleepy - can cause pneumonic infection - can also cause pericardial abscesses |
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- Taylorella equigenitalis causes ?
Are serlogical tests available? |
Taylorella equigenitalis causes Contagious Equine Metritis (CEM), animal becomes sterile
- exotic disease, UK, ireland, etc. - eradicated in US NO sero.tests |
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o What causes 1. KENNEL COUGH in dogs, 2. feline bronchopneumonia in cats,
3. causes ATROPHIC RHINITIS in pigs? |
Bordetella bronchiseptica
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- Moraxella bovis causes ?
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Moraxella bovis: causes Infectious Bovine Kerato-Conjunctivitis (IBKC) or “Pink eye” in cattle
* has pilli and attaches to cornea and produced enzymes which damage cornea, cause opacity of cornea and blindness |
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Moraxella bovis treatment?
antibiotics? vaccines? |
* penicillin locally
* tetracycline (oxytetracycline) parenteral o Pilus vaccine available o Treatable in early stages o Flies may transmit infection, use fly repellant tags o Keep animals away from sunlight |
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- Intracellular bacterium
- DOES NOT KILL ANIMALS - Causes ABORTION - genital disease, predilection site is uterus and male genital tract |
Brucella (B. abortus)
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Brucella causes
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Brucella causes: endometritis, placentitis, semen abnormalities
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Are there vaccines for treating brucella?
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Live vaccine available, doesn’t work well at all; can infect humans (old, live vaccine)
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Brucella intracellular bacterium, but can it survive in external environment for long time?
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yes, for approx. 6 months
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Is brucella a saprophyte?
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No
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Is brucella communicable to humans?
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- All form of Brucella are communicable to humans EXCEPT B. bovis
(B.canis, B.suis, B.abortus, etc are zoonotic) |
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Antibiotics for food producing animals with brucella?
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Do not use antibiotics in Brucella infected food producing animals
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- Gram neg curve bacteria (3)
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Campylobacter, Lawsonia intercellaris, Helicobacter
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Campy. jejuni causes ?
can it cause abortion? |
o Causes diarrhea in humans, dogs and cats
o Abortion rarely |
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Lawsonia intercellaris causes? in ?
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- Causes Porcine intestinal adenomastosis (PIA) in pigs
- Thickening of intestine, animal will have chronic diarrhea like “garden hose” |
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Treatment for Lawsonia intercellaris?
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- No vaccines
- Treat with tylosin (macrolide-class antibiotic) |
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NAME spiral bacteria belonging to spirochete group, any spirals unlike camphylobacter (curvy)
- Has several serotypes - Predilection site is kidney!!!!!!!!!! Excreted in URINE – contaminates water sources and humans and animals can get infections by drinking contaminated water |
Leptospira
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Carriers of leptospira?
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rodents
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Leptospira infectious to dogs and cats?
Zoonotic? |
No, cats can't get leptospira..can eat as many dead rats as they want
Yes, zoonotic |
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- L. icterrohaemorrhagiae is associated with dogs; what condition?
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L. icterrohaemorrhagiae (dogs) -> jaundice
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What STRAINS of leptospira associated with dogs? (2)
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L. canicola
L. icterrohaemorrhagiae (can be fatal i think) |
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Treatment for Leptospira?
Are vaccine available? Be specific why, why not |
Good vaccines available
- There are vaccines for dogs – outer sheath protein Ag - Tx: penicillin, streptomycin, tetracyclines, DOXYCYCLINE for dogs |
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Brachyspira
- B. hyodysenteriae Causes? Treatment? Vaccine? |
* Causes swine dysentery
o Gram stain: fecal material, spiral bacteria seem o Culture on special BA (anaerobic) o No vaccines (intracellular?) o Tx: tylosin (spirocete = tylosin) o Disinfect area and keep animals off for 2 months |
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Leptospira can cause meningitis in humans?
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True
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Brachyspira hyodysenteriae causes?
in ? aerobic? carriers? |
Brachyspira hyodysenteriae causes: swine dysentery
anaerobic, O2 tolerant Disease limited to intestine Carrier pigs (rats, mice temporary) |
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Treatment for brachyspira hyodysenteriae ?
Hint: what's good antibiotic for curvy & spirocetes? |
* Antibiotics (e.g. Tylosin) in feed for prevention and treatment effective
* Sanitation/ disinfection concurrently Rest for 60 days (organism dies off) * Replacement pigs – from known source Quarantine and medication |
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How to culture - B. hyodysenteriae?
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Culture on special BA (anaerobic)
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Swine dysentery: Clinical signs
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Swine dysentery: Clinical signs, lesions (hemorrhagic colitis)
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Borrelia: B. burgdorferi causes?
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LYME DISEASE
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Treatment for lyme disease?
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Treatment/ control: doxycycline (tetracycline) or other antibiotics 4 weeks
Vaccine (outer sheath antigen – ospA), tick control |
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What do all have in common?
Fusobacterium Mycoplasma Chlamydiae Ehrlichia Rickettsia |
Non spore-forming anaerobes
Fusobacterium Mycoplasma Chlamydiae Ehrlichia Rickettsia |
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causes calf dyptheria
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- Fusobacterium necrophorum
Two forms of calf diphtheria. Most common is acute oral (mouth) infection, seen in calves less than 3 mo. old. Second form is seen in older calves and affects the larynx, Both caused by Fusobacterium necrophorum, which also causes foul-in-the foot and liver abscesses in older cattle. |
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- Causes contagious bovine pleuropneumonia (CBPP) in cattle
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Mycoplasma mycoides
- No cell wall - anarobe, non spore forming |
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Is contagious bovine pleuropneumonia (CBPP) in cattle fatal?
What causes it? |
Yes
Mycoplasma mycoides causes contagious bovine pleuropneumonia (CBPP) |
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Can you culture Mycoplasma on Mac or BA?
Are vaccine available for Mycoplasma? Antibiotics? |
No, can't culture this way, they need a soft agar media with 20% serum
No, vaccine not available, and antibiotics may creat carrier state in CBPP; test and slaughter policy practiced -> with less contagious Mycoplasma diseases, tylosin a/o tetracycline are effective |
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Can mycoplasma mycoides kill dogs in large numbers?
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No
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Is mycoplasma mycoides endemic to US or exotic disease?
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exotic dz
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Mycop. gallisepticum causes ?
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M. gallisepticum
* causes chronic respiratory disease (CRD) in chickens |
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Mycop. felis causes ?
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conjunctivitis in cats
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Chlamydiae, Ehrlichia, Anaplasma, Rickettsia, Neorickettsia, Coxiella, Bartonella: all treated with ??
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Clamydiae, Ehrlichia, Anaplasma, Rickettsia, Neorickettsia, Coxiella, Bartonella: all treated with TETRACYCLINE
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Clamydiae, Ehrlichia, Anaplasma, Rickettsia, Neorickettsia, Coxiella all treated with ?
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: all intracellular bacteria; treated with tetracycline
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- Causes: TRACK FEVER in dogs and hemorrhagic fever
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Ehrlichia canis:
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Ehrlichia does not affect ??
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Ehrlichia does not affect cats
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___ causes ROCKY MOUNTAIN SPOTTED FEVER
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Rickettsia
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Rickettsia (RMSF) is disease in ?
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Rickettsia in dogs and humans; does not affect cats
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Neorickettsia causes ___ in ____
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Neorickettsia causes salmon poisoning in dogs, not cats
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Coxiella burneti causes ____ in _____
How transmitted? |
Coxiella burneti causes Q FEVER in ruminants and humans
- can infect placenta, abortion, fluid infective e.g. milk, urine, feces - zoonotic pathogen! |
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vector for ehrlichea?
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ticks
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causes "cat scratch disease"
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bartonella
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cause ovine foot rot
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- Fusobacterium necrophorum + Dichelobacter nodosus
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T/F Potomac Horse Fever (Neorickettsia/Ehrlichia) can cause abortion ?
T/F Potomac Horse Fever (Neorickettsia/Ehrlichia) not fatal |
True
False, up to 30% cases are fatal |
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Anaplasma and Neorickettsia are treated with ?
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oxytetracycline
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Can cause mastitis in cattle? (5)
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Streptococcus (3)
Actinomyces pyogenes Enterobacteriaceae coli -> coliform Klebsiella pneumoniae Pseudomonas aeruginosa |
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Can cause UTI in dogs? (name 5)
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Enterobacteriaceae coli
Klebsiella pneumoniae Proteus mirabilis Pseudomonas aeruginosa Staphylococcus (3) |
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Is mycoplasma fatal in dogs?
Is mycoplasma fatal in cattle? |
No, not usually
- M. mycoides fatal in cattle, but mild in dogs |
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Causes pneumonia in cattle?
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Enterobacteriaceae coli -> cattle
Klebsiella pneumoniae -> cattle Pasteurella multocida -> cattle Pseudomonas aeruginosa -> dogs and cats, sheep, cattle |
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Can you use penicliin for mycoplasma infection?
Why? |
No, have no cell wall
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Where might one find mycoplasma infection?
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Respiratory illnesses in ruminants (CBPP) and pigs
Also conjuctivitis in cats MYCO MYC...Ck Bt Plw Pfr |
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Aside from Mycoplasma, what else could cause conjunctivitis in eye of cat?
What antibiotic could you use to treat both? |
Chlamydia
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Salmonella enterica causes disease in?
Salmonella dublin causes disease in? |
not species specific; all animals
Dublin? in cattle, sheep, horses, dogs |
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Salmonella typhimurium causes disease in?
Salmonella typhi causes disease in? |
many animals, humans included
humans |
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Salmonella cholerasuis causes disease in?
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pigs
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which salmonella serovar causes disease in chicks? in US?
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Salmonella pullorum, called Pullorum disease; not common in US
Hint: both bird serovars end w/-rum |
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Which salmonella serovar causes disease in adult birds outside US?
What name of disease? |
S. gallinarum, disease called Fowl typhoid; not common in US
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Which pathogen causes typhoid in humans?
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Salmonella typhi
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Hemorrhagic Colitis is associated with what ?
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Shiga toxin producing E.coli (STEC), a pathogenic strain
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E.coli O157: K88 ; H2 (pig)
Pathogenic strains are classified by serotyping. What antigens are {O, K, H} associated with? |
O: cell wall
K: capsule and pilli antigen H: flagella |
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Which of following is not a "coliform"?
Klebsiella E.coli Salmonella Streptococcus |
Coliform bacteria are Gram-negative non-spore forming rods which can ferment lactose.
Therefore, Salmonella (NLF) and Strep (gr+) cannot be included |
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Can coliforms cause mastitis in cattle?
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yes
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Atrophic Rhinitis
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Pasteurella multocida -> pigs
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