Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
20 Cards in this Set
- Front
- Back
|
Bacterial pathogenesis
|
the study of the methods used by pathogens to cause disease or to infect cells
|
|
|
opportunistic pathoges
|
pathogens that cause disease in immunologically suppressed individuals only
ex: e. coli, c. tetani, Klebsiella |
|
|
Virulent
|
promotes pathogenicity
|
|
|
Successful infection
|
portal of entry
adherence (binding) colonization & invasion damage to host exit from host survival of organism for more transmission |
|
|
Virulence factors
|
factors that assist in causing diease
ex: capsules, pili, endo/extotoxins |
|
|
Portals of Entry
|
mucous membranes, skin, parenteral route
|
|
|
Preferred Portal of entry
|
must gain through preferred method, use virulence factors or mechanisms to survive
|
|
|
numbers of bacteria
|
most bacteria need high numbers to colonize
|
|
|
adherence
|
bacteria must be able to stick to a cell surface long enough to establish infection. ligand binds to host cells surface receptor
-skin sheds -cilliary beds in resp. tract |
|
|
phase variation
|
when the host makes antibodies to pili, the bacteria can alter the type of pili made
|
|
|
glycocalyx
|
sticky polysaccharide that binds some pathogens to surfaces
|
|
|
facilitated entry
|
bites, burns, abrasions, cuts, wounds, surgery
|
|
|
colonization
|
microbes must obtain conditions that allow multiplication, have to compete with normal flora for resources and food
|
|
|
obligate intracellular pathogens
|
Chlamyida and ricksettsia, viruses must reproduce inside cells so they must depends on host cells for everything
|
|
|
extracellular organisms
|
live outside cells
|
|
|
Capsules
|
prevent phagocytosis
|
|
|
Toxin
|
substance that cotnributes to pathogenicity
|
|
|
Toxigenicity
|
ability to produce a toxin
|
|
|
Toxemia
|
presence of toxin in the hosts blood
|
|
|
Toxoid
|
Inactivated toxin used in a vaccine
|
