Bacterial, Parasitic, And Ectoparasitic Sti's

Front 1

gram negative diplococci
coffee bean shape

Back 1

neisseria gonorrhoeae

Front 2

fastidious, requires enriched growth medium, increased concentrations of CO2
ox pos
weak acidic products on trypticase agar

Back 2

neisseria gonorrhoeae

Front 3

causes purulent discharge, dysuria, frequency

Back 3

neisseria gonorrhoeae

Front 4

affects more females than males
female carriers are estimated to be over 30%

Back 4

neisseria gonorrhoeae

Front 5

urethritis, cervicitis, proctitis, pharyngitis, conjunctivitis, epidymitis, PID, arthritis

Back 5

neisseria gonorrhoeae

Front 6

pathogenesis: sexual contact with infected mucosal tissues and specific attachment due to pilli

Back 6

neisseria gonorrhoeae

Front 7

spread is due to invasion of membranes- nonciliated columnar epithelium and creates acute suppuration- may go to the uterine tubes or epididymis; in severe infections, may spread to the stream and invade joints

Back 7

neisseria gonorrhoeae

Front 8

no protective immunity- repeated exposure will lead to re-infection

Back 8

neisseria gonorrhoeae

Front 9

pili
lipooligosaccharide that causes inflammation andtissue damage
outer membrane proteins- strain variation
IgA1 protease

Back 9

neisseria gonorrhoeae

Front 10

what are the outer membrane proteins in neisseria gonorrhoeae?

Back 10

1- porin
2- opacity that renders the colonies colorless
3- reduction- modifiable proteins stimulate Ab to ind IgG and interfere with intracellular killing

Front 11

collect specimen from cervix or male urethra and do a gram stain
-in males, gram stain with polys and gram neg diplococci are positive
in females, need culture

Back 11

neisseria gonorrhoeae

Front 12

neisseria that metabolizes glucose

Back 12

neisseria gonorrhoeae

Front 13

neisseria that metabolizes glucose and maltose

Back 13

neisseria meningitidis

Front 14

grows on nutrient agar

Back 14

moraxella catarrhalis- grows on nutrient agar but resembles neisseria on slide

Front 15

twar strain

Back 15

chlamydia pneumonia

Front 16

obligate intracellular parasite with two forms- elementary infectious body and reticulate (non-infectious) body

Back 16

chlamydia trachomatis

Front 17

resembles a gram negative bacteria

Back 17

chlamydia trachomatis

Front 18

ulcer on genitalia is initial symptom

Back 18

chlamydia trachomatis

Front 19

suppurative inguinal adenitis, lymphatic obstruction and rectal strictures

Back 19

chlamydia trachomatis

Front 20

urethritis in males
females: mucopurulent cervicitis, salpingitis, PID

Back 20

chlamydia trachomatis

Front 21

neonate: inclusion conjunctivitis and pneumonia

Back 21

chlamydia trachomatis

Front 22

what happens if you don't treat conjunctivitis in a newborn that is infected with chlamydia trachomatis?

Back 22

blinding trachoma- chronic keratoconjunctivitis leading to corneal scarring and blinding

Front 23

steadily increasing incidence with twice as many men as women

Back 23

chlamydia trachomatis

Front 24

blinding chlamydia spread by

Back 24

person to person or fomites

Front 25

infect cells by attaching to them and becoming phagocytosed and then avoiding lysosomal fusion

Back 25

chlamydia trachomatis

Front 26

non-replicating elementary bodies metabolically activate to reticulate bodies and develop into elementary bodies
then they lyse and leave the host cell to start a new infection

Back 26

chlamydia trachomatis

Front 27

direct antigen testing by EIA or ELISA to id
DFA stain
isolationin mccoy cell line
inclusions in conjunctival scrapings

Back 27

chlamydia trachomatis

Front 28

ddx for urethritis and cervicitis with mucopurulent discharge

Back 28

gonorrhea
chlamydia

Front 29

ddx for vaginits with mucopurulent discharge

Back 29

bacterial vaginosis
candidiasis
trichomonas

Front 30

genital ulcers

Back 30

herpes
syphilis
heamophilus ducryei

Front 31

warts

Back 31

HPV
secondary syphilis

Front 32

ectoparasite

Back 32

phthirus pubis
sarcoptes scabeie

Front 33

vaginal pH
thin homogenous vaginal discharge that contains clue cells
release of an amine- like odor when mixed with 10% KOH

Back 33

bacterial vaginosis

Front 34

causes of bacterial vaginosis

Back 34

gardnerella vaginalis
mobiluncus sp

Front 35

curved anaerobic gram negative rods

Back 35

mobiluncus

Front 36

malodorous frothy discharge associated with burning, itching, chafing, diffuse vaginal erythema

Back 36

thrichomoniasis

Front 37

diffuse papulsquamous eruption
(palms and soles)

Back 37

treponema pallidum

Front 38

long thing helical bacteria with rotary motility and a gram negative wall
lacks endotoxin

Back 38

treponema pallidum

Front 39

causes syphilis

Back 39

t. pallidum

Front 40

causes yaws

Back 40

t. pertenue

Front 41

occurs in the warm humid tropics
raspberry-like sores that are painless first, then development of bone pain and swelling of hands and fingers

Back 41

yaws

Front 42

causes pinta

Back 42

t. carateum

Front 43

red scaly lesions on the skin with disfiguring pigment changes

Back 43

pinta

Front 44

small mucous patch, then raised, eroding lesions on limbs and trunk
periostitis of leg bones is common and gummas of the nose and soft palate develop in later stages

Back 44

bejel

Front 45

causes bejel

Back 45

t. endemicum

Front 46

painless ulcer is primary sign

Back 46

syphilis

Front 47

single chancre that develops 3 weeks after exposure and lasts about a month

Back 47

primary syphilis

Front 48

skin rash with infectious lesions that will resolve spontaneously

Back 48

secondary syphilis

Front 49

gummas develop on skin or other tissues
characterized by granuloma formation

Back 49

tertiary syphilis

Front 50

can be visualized on a wet mount with dark field microscopy

Back 50

syphilis

Front 51

chancroid is caused by

Back 51

haemophilus ducreyi

Front 52

soft chancre that is painful with a sloughy, purulent edge that bleeds easily

Back 52

haemophilus ducreyi

Front 53

is slow-growing on a culture of special media

Back 53

haemophilus ducreyi

Front 54

phthirus pubis

Back 54

pubic lice

Front 55

sarcoptes scabiei

Back 55

scabies

Front 56

itchy, reddish papules

Back 56

ectoparasites

Front 57

increases the risk of preterm delivery and infection with HIV

Back 57

trchomonas

Front 58

colpitis macularis

Back 58

strawberry cervix- punctate hemorrhages and vesicles or papules- seen in trichomonas

Front 59

elevated vaginal pH (>4.5) with increased neutrophils

Back 59

trichomonas

Front 60

infectious stage of trichomonas?

Back 60

trophozoite

Front 61

globular-like cell with 3-5 flagella, undulating membrane, single oval nucleus

Back 61

trichomonas vaginlis