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39 Cards in this Set
- Front
- Back
Which bug should you first consider in adults with regards to menigitis?
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S. pneumoniae
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Which bug should you first consider in neonates with regards to menigitis?
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Group B strep
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Which bug should you first consider in adolescents with regards to menigitis?
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Neisseria meningitis
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Properties of Streptococci
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Gram +
Catalase negative Ferment sugars |
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What are the three classifications of streptococci?
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Beta-hemolysis
Alpha-hemolysis Gama-hemolysis |
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Which streptococci causes complete hemolysis?
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Beta
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What lab test is used for S. pneumoniae?
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Optochin S
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Which kind of hemolysis does S. pneumoniae cause?
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Alpha (incomplete)
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Name a group B strep
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S. agalactitae
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Lab test for S. agalactiae
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Hippurate hydrolysis pos
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What kind of capsule does S. agalactiae have?
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Sialic acid
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Charcteristics of S pneumoniae
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Grap pos
LANCET shaped diplocci Alpha hemolytic Polysaccharide capsure Pneumolysin C-reactive protein! |
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S. pneumoniae
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Diseases caused by S. pneumoniae
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Pneumonia
Sepsis Meningitis Otitis media Sinusitis Conjunctivitis |
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Neisseria meningitidis charcteristics
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Gram -
Diplococci Coffee bean shaped Ox + Ferments MALTOSE and GLUCOSE Capsule |
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Virulence factors of N. meningitidis
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Pili
Capsule LOS IgA protease |
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Characteristics of H. influenzae
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Small, gram -
Pleomorphic Fastidious Rods |
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Which capsule type of H. influenzae is most invasive?
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type b
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What are the virulence factors of H. influenzae?
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Endotoxin
Neuraminidase IgA protease Fimbriae |
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How do you grow H. influenza?
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X factor - hemin
V factor - NAD on chocolate agar |
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Virulence of Listeria monocytogenes?
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Listeriolysin O (pore forming allowing it to escape phagocytosis)
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Characteristics of Listeria monocytogenes
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Short gram + rods
Tumbling motility Beta hemolytic |
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Where do pathogens enter the brain?
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Penetrates BBB at choroid plexus
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What is Waterhous-Friderischsen syndrome?
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Invasion of N. meningitis to adrenal gland
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Should you initiate antimicrobial therapy prior to imagining studies?
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Of course you silly goose
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When examining CSF how many tubes should be collected?
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3 - cell count, gram stain, chem analysis
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What would aid you to a differential of bacterial meningitis in CSF with regards to:
Glucose Protein Cell count Cell type |
Glucose 20-40
Protein >100 Cell count >1000 Cell type >50% PMNs |
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TX for S. pneumoniae
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Pen G
or Vancomycin in Pen resist |
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TX for N. meningitidis
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Pen G
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TX for H. influenza
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Cefotaxime or ceftazidime
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TX for GRB
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Pen G
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TX for prophylaxis of N meningitidis
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Rifampin
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Polysaccharide vaccines induce
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T-independent Ab responses
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Conjugated vaccines induce
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T-dependent Ab responses
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Chronic meningitis bugs
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TB
Syphilis Lyme disease Cryptococcosis Coccidiomycosis Hisoplasmosis |
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What confirms Syphilis Meningitis?
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VDRL in CSF
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DOC for Lyme meningitis
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Ceftriaxone
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Brain eating amoeba
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Naegleria fowleri
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Groups that are effected by Toxoplasma gondii
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HIV
Pregos |