Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
18 Cards in this Set
- Front
- Back
|
Vibrio cholerae
|
Cholera
|
|
|
What are the main properties of Vibrio cholerae ?
|
gram negative
facultatively aerobic curved rods |
|
|
Where is Vibrio cholerae found?
|
Brakish waters and estuaries (Flussmündung).
|
|
|
How does transmission of V. cholerae happen?
|
By contaminated water ( has high ID).
|
|
|
What is the virulence factor of V. cholerae?
|
Production od cholera toxin.
|
|
|
what are the symptoms of cholera?
|
Watery diarrhia,
Muscle cramps as water and electrolytes are lost from tissue. |
|
|
What does the cholera toxin do?
|
Causes host cells to secrete Cl-, HCO- and water.
|
|
|
How does V. cholerae invade into the host cells?
|
Adhesion to epithelium,
activation of type III secretion system, bacterial ubstance enters the cell by ENDOCYTOSIS, multiplication within PHAGOSOME discharged by EXOCYTOSIS, INFLAMMATORY response > fluid secretion > DIARRHIA |
|
|
What is HEPATITIS in general?
|
Inflammation of the liver.
|
|
|
Where does HEPATITIS result from?
|
drugs/chemical toxicity,
Epstein-Barr virus (EB) Cytomegalovirus (CMV) Hepatitis viruses (A-E) |
|
|
What kind of virus is the Hepatitis A virus?
|
RNA picornavirus, lacking of envelope, free RNA.
|
|
|
What is the host of Hepatitis A?
|
Humans only.
|
|
|
How does the Hepatitis A enter the human body and where does it spread?
|
Via oral route (food or water).
Multiplication in intestinal epithelia, spread to liver, kidney, spleen (MIlz). |
|
|
How can Hepatitis A be found first?
|
In feces highest numbers are present before symptoms appear.
|
|
|
What is the incubation period of Hepatitis A?
|
Average 30 days,
Range 15-50 days. |
|
|
What are the symptoms of the acute disease of Hepatitis A?
|
anorexia, malaise, nausea, diarrhia, abdominal discompfort, fever, jaundice (Gelbsucht).
Virus only shed during acute state. |
|
|
What kind of Infection is Hepatitis A?
|
NO chronic infection, protective antibodies are developed as response to infection > Lifelong immunity!
|
|
|
what kind of Virus is Hepaptitis B?
|
DNA Hepadnavirus, enveloped.
Three distict particles... high infection rate for people whoa re in contact with blood in daily life. |
