Bacteria That Do Not Gram Stain #2 4/20

Front 1

9. What is the name of the bacteria that causes Lyme Disease?

Won't find ticks at Burgdorf's

Back 1

Borrelia burgdorferi

Front 2

10. Describe the Mycoplasma pneumoniae? (size, cell wall, stabalization, and appearance)

Back 2

Smallest free-living bacteria
No cell wall
Host sterols stabilize cell membrane
Fried egg appearance on media

Front 3

11. Name 2 Disease Associations of Mycoplasma pneumoniae?

Back 3

Upper respiratory tract infections
Low grade fever, headache, non-productive cough lasting > 2weeks
Lower respiratory tract infections
Tracheobronchitis
Pneumonia (“atypical pneumonia")

Front 4

12. Describe (“atypical pneumonia")

Mycoplasma pneumoniae is a human pathogen transmitted by infections aerosols, what is it the most common cause of?

Back 4

Diffuse X-ray
Non productive cough

walking pneumonia

Front 5

13. what happens to the cilia in Mycoplasma pneumoniae

Back 5

they die, leading to increased mucus and bacteria, and decreased healing
like whooping cough

Front 6

14. What is the clinical name for TB?

What is the unique acid characterisitc? (similar to leporsy)

How many people around the world are infected with TB?

It can hang out in the air for several hours!

Back 6

Mycobacterium tuberculosis

Acid Fast positive

1/3

Front 7

14. What is the pathogenesis of
TB?

Back 7

Organism is phagocytosed and grows in alveolar macrophages
Avoids killing by preventing fusion of phagosome with lysosomes
In immune competent individuals, CMI activates infected macrophages and stops growth of bacteria
Bacteria in macrophages do not die, but are walled off
Re-activation may occur within 2 years
Clinical manifestations
Cough productive of bloody sputum, fever, night sweats, weight loss

Front 8

15. Can TB survive in Marcophages for years?

How is the lung damaged in TB?

Back 8

Bacteria in the macs do not die, just walled off in granulomatous masses

the Host responce to the organism