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24 Cards in this Set
- Front
- Back
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What is the most common zoonosis disease in the world?
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leptospira
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How can humans get leptospira?
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contact with fresh water contaminated by bovine, rat, canine or wildlife urine
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What is an example of a pathogenic organisms or serovars of leptospirosis?
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1. leptospira interrogans serovar canicola
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What is an example of a nonpathogenic leptospira?
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leptospira biflexa
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Are serovars for lepto species specific?
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yes, they seem to be
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How do you diagnose leptospirosis?
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serology
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What are two types of leptospira?
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1. host adapted
2. non host adapted |
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What is host adapted lepto?
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-infection results in animal becoming a reservoir
-infections are endemic |
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What is non host adapted lepto?
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-infection causes accidental or incidental disease
-results in sporatic infections or outbreaks -previous infection with host-adapted serovar can decrease severity of infection with non-host-adapted serovar (shared pathogens) |
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How does lepto enter the body?
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-through nasal, oral or conjunctival membranes or skin lesions
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During acute infection, leptospira multiply where? resulting in?
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-multiply in capillary endothelium resulting in damage and vasculitis
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What will you see in a liver affected by lepto?
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centrolobular necrosis, kupffer cell proliferation, hepatocellular dysfunction
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why can you look at outbreaks of lepto in dogs or humans to determine what lepto strain is affecting which species?
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infecting serovars in humans are antigenically related to emerging serovars in dogs
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What stain do you use to id lepto?
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silver nitrate stain
-black structures will be spirochetes with a yellow background tissue |
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What is borrelia burgdoferi?
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a spirochete
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What disease does borrelia burgoferi cause?
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lyme disease
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What spirochete causes lyme disease?
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borrelia burgoferi
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What are two more spirochetes besides burgdofi that have been found to cause lyme disease?
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borrelia garinii and afzelii
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How is lyme disease trasmitted?
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ticks
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what are the main clinical signs of lyme disease in humans?
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rashes followed by joint, cardiac or neurologic disease
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what are the predominate signs of lyme disease in a dog?
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appetite loss, fever, lameness with arthritis, lymphadenopathy, renal disease, cardiac and neurological disorders
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What does lyme disease look like in horses and cattle?
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arthritis, encephalitis, uveitis, and laminitis
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What is the basis vaccines for lyme disease?
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outer surface proteins are the basis for vaccines
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What is the life cycle length of borrelia burgdofi?
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2 years
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