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26 Cards in this Set

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What is the cell wall of spirochetes made of?
peptidoglycan
Where a axial fibers found in spirochetes?
Between the protoplasmic cylinder and the outer envelope
What three genera of spirochetes are pathogenic for animals and humans?
Borrelia
Leptospira
Brachyspira
What is an infection of borrelia theileri characterized by?
febrile episodes, weight loss, weakness, and anemia.
When can Borrelia theileri be found in the blood of an infected individual?
during the febrile state
Where can Leptospira sequester in order to evade immune attack?
renal tubules
uterine lumen
eye
brain
What spirochete causes colitis in growing pigs?
Brachyspira pilosicoli
What spirochete can cause fever depression and profuse diarrhea in birds?
Borrelia anserina
With infection of this organism, in dogs the dominant clinical sign is acute lameness.
Arthritis, encephalitis, uveitis and laminitis have been described in infected cattle and horses. What is it?
Borrelia Burgdorferi
What are the host-adapted serovars for the following:
cattle, swine, dogs, horses, deer, rodents
cattle-hardjo
swine-bratislava
dogs-canicola
horses-bratislava
deer-pomona
rodents-icterhaemorrhagiae
How does lepto enter the body?
nasal, oral, conjuctival membranes or skin lesions
This organism causes swine dysentery which is marked by bloody diarrhea.

what organism resembles this organism?
Brachyspira hyodysenteriae

B. innocens
What secondary agents are necessary for disease to develop from B. hyodysenteriae?
Bacteroides fragilis
fusobacterium
This spirochete is contracted by ingestion of contaminated feces from a recently infected or a carrier animal.
B. hyodysenteriae
what lesions might a pig with tuberculosis present with?
lesions in the mandibular and mesenteric lymph nodes.
may develop granulomatous lesions in the intestinal mucosaor tonsils
Waht drug binds to the 30s ribosomal subunit and inhibits vacterial protein synthesis?
Streptomycin
what drug interferes with lipid and DNA synthesis inhibiting bacterial cell wall synthesis?
Isoniazid
What drug impairs RNA synthesis by inhibiting DNA-dependant RNA polymerase?
Rifampin
what drug interferes with mycolic acid incorporation into the mycobacterial cell wall?
Ethambutol
what does C. pseudotuberculosis cause in sheep and goats?

what about horses?
caseous lymphadenitis in sheep and goats

Ulcerative lymphangitis in horses
What are the virulence factors for Rodococcus equi?
Vap A
cholesterol oxidase
Arabinogalactan capsule
What are the proposed virulence factors for Erysipelothrix?
Hyaluronidase and Neuraminidase
What drugs are commonly used to treat E. rhusiopathiae?
Pen G and ampicilin
What causes circling disease in sheep, head pressing, facial paralysis, difficulty in swallowing, fever, and blindness?
Listeria
What is the major virulence factor that allows Listeria to escape the phagosome after ingestion?
Listeriolysin
What surface protein is necessary for Listeria to induce actin filament assembly?
ActA