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8 Cards in this Set
- Front
- Back
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where is AID expressed |
in dark zone expressed by centroblasts |
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when does testing of affinity in LZ end |
until germinal center run out of Ag or B cells are sufficiently high affinity |
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SMH |
AID converts C --> U in openly transcribed DNA |
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isotype switching |
process by which B cells change the function of the antibody produced |
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IgM function |
complement activation and initial killing of microbes |
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IgG function |
main serum antibody neutralization, degradation, NK cell activation and complement activation |
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IgA function |
main mucosal antibody microbial neutralization (preventing entry) |
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IgE function |
epithelial surfaces antibody Bind to Fc receptors on mast cells and basophils |
