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18 Cards in this Set
- Front
- Back
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Acute Lymphadenitis
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Painful bacterial infection
Micro - PMNs |
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Chronic nonspecific Lymphadenitis
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3 patterns
1 Follicular hyperplasia 2 Paracortical T-Cell 3 Hyperplasia Sinus histiocytosis |
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Follicular hyperplasia
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Lymphadenitis
Seen w/ autoimmune disease like RA Seen w/ HIV |
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Paracortical T-Cell Hyperplasia
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Lymphadenitis
EBV - Mono Seen after vaccination Seen w/ Catscratch disease |
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Sinus histiocytosis
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Lymphadenitis
Seen in benign lymph nodes draining cancers |
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Specific - granulomatous Lymphadenitis
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TB or foreign bodies
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B-cell Lymphomas
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Follicular
Diffuse Large B Burkitt Mantle Marginal / MALT |
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Follicular Lymphomas
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B-Cell Lymphomas (CD19 and 20)
Adult Nodal Indolent Incurable Molecular: 14:18 translocation BCL-2 |
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Diffuse Large B Lymphomas
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Diffuse
Any age All other lymphomas can end up as this Aggressive – grows rapidly Is curable 50% of the time BCL-6 |
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Burkitt Lymphomas
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Aggressive
“Starry Sky” morphology T8:14; Myc Burkitt in US – child w/ intestinal lymphoma (illiocecal valve); not associated w/ EBV Burkitt in HIV – +/- EBV African Burkitt – 100% EBV; maxilla and mandible;; be able to recognize |
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Mantle Lymphomas
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Intermediate
For years BCL-1, Cyclin D T11:14 Nodal Adult |
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Marginal / MALT Lymphomas
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H. Pylori in stomach
5% of gastric malignancy The lymphoma that occurs in Sogren Syndrome |
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T-cell Lymphomas
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Adult T-leukemia/lymphoma
Mycosis fungoides/Sezary syndrome Anaplastic large-cell lymphoma Extranodal NK lymphoma |
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Adult T-leukemia/lymphoma
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T-cell Lymphoma
CD3 & CD4 Due to HTLV1 |
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Mycosis fungoides
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T-cell Lymphomas
CD3 & CD4 Skin manifestations Adult Mycosis: Patch Plaque Nodule (takes years) --indolent variety |
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Sezary syndrome
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T-cell Lymphomas
CD3 & CD4 Skin manifestations Adult Sezary: Lymphoma from day 1; Red Man syndrome Aggressive |
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Anaplastic large-cell lymphoma
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T-cell Lymphoma
Marker is ALK Good prognosis lymphoma of children |
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Extranodal NK lymphoma
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T-cell Lymphoma
Necrotizing nasal pharyngeal lymphoma due to EBV Rare |
