Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
43 Cards in this Set
- Front
- Back
What is the Basic Cholergenic Neurotransmitter
|
ACH
|
|
Used to Increase GI Motility, Muscarenic agaonist
|
Bethanechol
|
|
Muscarenic Agonist, used only for eye drops in glaucoma
|
Carbachol
|
|
This increases BP and HR especially
|
Nicotine
|
|
Muscarine activates
|
PNS + Sweating
|
|
Atropine?
|
Blocks all the muscarenic receptors
|
|
Anti Nicotenic, paralyses the NMJ
|
Curare
|
|
Ganglionic Blockers, increase BP while depressing all PNS activity
|
Hexamethonium/Trimethaphan
|
|
Physostigmine
|
ACHE inhibitor, can cross the BBB
|
|
Less powerful ACHE inhibitor, more commonly used
|
Neostigmine
|
|
ACHE inhibitor that acts for 15min
|
Edrophonium
|
|
Organiphosphates, sarin
|
Irreversible ACHE binders, activate the PNS a lot
|
|
Cleaves the ACHE from organophosphates
|
Pradlidoxime
|
|
Given to alzheimers patients to increasing their circulating ACH
|
Donepezil
|
|
Anti Muscarenic drug given for bladder control
|
Oxybutynin
|
|
Epi is a aganosit for
|
Beta 1 Beta 2 and Alpha 1
|
|
Nor Epi is a agonist for
|
Alpha 1,2 Beta 1
|
|
B1 B2 Agonist
|
Isoproterenol
|
|
Alpha 1 only agonist
|
Phelylephrine
|
|
Alpha 1 receptor blocker
|
Phentaloamine
|
|
Metyrosine
|
Blocks TH and dopamine synth
|
|
L-Dopa
|
can b given to skip the TH step
|
|
Alpha 2a agonist, alpha 2b agonist, given for hypertension for brain stuff
|
Clonidine
|
|
Tyramine
|
In cheese, broken down by MOIs, can cause hypertension if levels are too high
|
|
Amphetamine
|
blocks the NE pump back into cell, MAO blocker, VAMT blocker
|
|
Ephedrine
|
Causes a release of NE, partial NE agonist
|
|
Cocaine
|
Inhibits reuptake of Dopamine, Nor Epi, Seretonin
|
|
Main tricyclic antidepressant, NE reuptake inhibitor
|
Desipramine
|
|
Non Selective MAOI
|
Phenelzine
|
|
Selective MAOI
|
Selegiline
|
|
Phosphodiesterase Inhibitor, increase CAMP and effect similar to EPI or Nor Epi
|
Aminophylline
|
|
Viagra is also called
|
Sildenafil, increases cGMP in Penis especially, lungs too
|
|
Dopamine
|
Increases renal BF, Beta 1, alpha 1 agonist. Bad for heart failure
|
|
Dobutamine
|
Beta 1 agonist, only sorta a alpha 2 agonist, better for heart failure
|
|
Albuterol
|
Beta 2 agonist, lungs
|
|
Ritodrine
|
Beta 2 agonist, Uterus
|
|
Permanent alpha 1, 2 blocker
|
Phenoxybenzamine
|
|
Alpha 1,2,3 blocker, used for hypertension
|
Prazosin
|
|
Alpha 1 a blocker used for prostatic hypertension
|
Tamsulosin
|
|
Most common Beta 1,2 blocker
|
Propranolol
|
|
Selective Beta 1 blocker
|
Metoprolol
|
|
Beta Blocker with low agonist activity at Beta 1,2,
|
Pindolol
|
|
Alpha and Beta receptor antagonists
|
Carvedilol, Labetalol
|