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352 Cards in this Set
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Pronunciation of Atenolol
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a-TEN-oh-lol
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What is the brand name of Atenolol?
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Tenormin TM
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What is the Therapeutic Class of Atenolol
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Sympatholytic/Antihypertensive
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What is the Pharmacologic Class of Atenolol?
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Selective adrenergic Beta 1 receptor antagonist
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M.O.A of Atenolol?
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Competitively blocks Beta 1 receptors
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Clinical Uses of Atenolol
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Angina, hypertension
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Special Considerations of Atenolol
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Less lipophilic, fewer central nervous sytem side effects
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None
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Adverse Effects of Atenolol
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Bronchoconstriction with higher doses because of Beta 2 receptor blockade
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Interactions of Atenolol
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Additive hypotensive effect with nitrates and antihypertensive drugs/additve bradycardia with digoxin, decreases effects of dopamine and dobutamine
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Drugs similiar to Atenolol
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acebutolo, betaxolol, bisoprolol, ESMOLOL, metoprolol
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Pronunciation of Atropine
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AT-roe-peen
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What is the brand name of Atropine?
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Atro-Pen TM
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What is the Therapeutic Class of Atropine
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Anticholinergic agent
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What is the Parmacologic Class of Atropine
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Muscarinic receptor antagonist
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M.O.A. for Atropine
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Competitively blocks all muscarinic receptors
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Clinical Uses of Atropine
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Bradycardia and atrioventricular block, irritable bowel symptoms, anticholinesterase poisoning
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What are the Special considerations when using atropine?
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Can slow heart rate when first administered
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What are the adverse effects of atropine?
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Tachycardia, mydriasis and cycloplegia, warm, dry, flushed skin, delirium, and hallucinations
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Interactions of Atropine
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Additive anticholinergic effects with antihistamines (diphenhydramine) and tricyclic antidepressants (amitriptyline), slows absorbtion of other drugs by delaying gastic emptying
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Similiar drugs
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DICYCLOMINE, glycopyrrolate, hyoscyamine, IPRATROPIUM, oxybutynin, scopolamine, tolterodine
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Pronunciation of Dobutamine
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doe-BUE-ta-meen
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Brand name of Dobutamine
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Dobutrex TM
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Therapeutic Class of Dobutamine
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sympathomimetic, cardiac stimulant
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Pharmacologic Class of Dobutamine
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Selective Beta 1 adrenergic receptor agonist
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M.O.A of Dobutamine
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Activates Beta 1 > Beta 2 >> Alpha 1 receptors, increases cardiac contractility and cardiac output > heart rate
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Clincial Uses of Dobutamine
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Acute heart failure and cardiogenic shock
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Special Considerations of using Dobutamine
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Administered by Intravenous infusion
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Adverse effects of Dobutamine
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Tachycardia and arrhythmia
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Interactions
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Synergistic effect on cardiac output with nitroprusside
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Similiar drugs to Dobutamine
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none
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Pronunciation of Edrophonium
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ed-roe-FOE-nee-um
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Brand name of Edrophonium
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Tensilon TM
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Therapeutic Class of Edrophonium
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Diagnostic agent
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Pharmacologic Class of Edrophonium
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Cholinesterase inhibitor
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M.O.A. for Edrophonium
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Reversibly binds and inhibits cholinesterase
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Clinical Use of Edrophonium
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Diagnosis of myasthenia gravis, differential diagnosis of myasthenic crisis and cholinergic crisis
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Special Considerations of using Edrophonium
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Very short-acting after intravenous administration
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Adverse Effects of Edrophonium
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Muscarinic effects (e.g. miosis, salivation)
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Interactions of Edrophonium
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None usually significant
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Similar drugs to Edrophonium
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neostigmine, physostigmine, PYRIDOSTIGMINE
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Pronunciation of Epinephrine
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e-pi-NEF-rin
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What is the brand name of Epinephrine?
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Adrenalin TM
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What is the therapeutic class of epinephrine?
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Sympathomimetic
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What is the Pharmacologic class of epinephrine?
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Nonselective adrenergic agonist.
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M.O.A for Epinephrine
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Activates alpha and beta receptors, increasing inositol triphosphate and cyclic adenosine monophosphate, alpha 1 - vasoconstriction and increased blood pressure, beta 1 - increased heart rate, conduction, and contractility, beta 2 - vasodilation and decreased diastolic blood pressure, bronchodilation
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Clinical Uses of Epinephrine
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Cardiac arrest, ventricular fibrillation, anaphylactic shcok, asthma, chronic obstructive pumonary disease
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Adverse Effects of Epinephrine
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Hypertension, tachycardia, ischemia, hyperglycemia
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Interactions of Epinephrine
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None usually significant
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Similiar drugs to epinephrine
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none
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Pronunciation of Phenoxybenzamine
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fen-ox-i-BENZ-a-meen
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What is the brand name Phenoxybenzamine
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Dibenzyline TM
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Therapeutic class of Phenoxybenzamine
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Vasodilator
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Phrmacologic Class
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Irreversible adrenergic alpha receptor antagonist
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M.O.A. for Phenoxybenzamine
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Blocks Alpha 1 > Alpha 2 receptors
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Clinical Use for Phenoxybenzamine
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Presurgical treatment of hypertension caused by pheochromocytoma
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Special Considerations for using Phenoxybenzamine
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Forms covalent bond with alpha receptor
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Adverse Effects of Phenoxybenzamine
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Postural hypotension
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Interactions of Phenoxybenzamine
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Hypotensive effect increased by beta-adrenergic blockers and calcium channel blockers
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Similar drugs to Phenoxybenzamine
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phentolamine
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Pronunciation of Phentolamine
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fen-TOE-la-meen
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Brand name of Phentolamine
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Regitine TM
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Therapeutic Class of Phentolamine
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Vasodilator
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Pharmacologic Class of Phentolamine
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Adrenergic alpha receptor antagonist
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M.O.A. for Phentolamine
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Competively blocks alpha 1 and alpha 2 receptors
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Clinical Use of Phentolamine
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Counteract vasoconstriction caused by accidental injection or extravasation of vasoconstrictors
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Special Considerations of Phentolamine
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Parenteral administration only
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Adverse Effects of Phentolamine
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Hypotension
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Interactions of Phentolamine
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Severe hypotension if give with epinephrine, blocks effects of alpha-adrenergic agonists
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Pronunciation of Phenylephrine
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fen-il-EF-rin
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Trademark
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Neo-Synephrine TM
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Therapeutic Class of Phenylephrine
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Vasoconstrictor
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Pharmacologic Class of Phenylephrine
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Selective adrenergic alpha 1 receptor agonist
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M.O.A. of Phenylephrine
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Activates alpha 1 receptors, increasing inositol triphospate and causing contraction of vascular smooth muscle
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Clinical Use
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Nasal and ocular decongestant
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Special Considerations of Phenylephrine
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Occular administration causes mydriasis with cycloplegia (paralysis of accomodation)
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Adverse Effects of Phenylephrine
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Rebound nasal congestion
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Interactions of Phenylephrine
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May cause severe hypertension if given with monoamine oxidase inhibitors
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Similiar Drugs
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norepinephrine, PSEUDOEPHEDRINE
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Pronunciation of Pilocarpine
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pye-loe-CAR-peen
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Brand name of Pilocarpine
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Salagen TM
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Therapeutic Class of Pilocarpine
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Antiglaucoma agent, sialagogue
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Pharmacologic Class of Pilocarpine
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Muscarinic receptor agonist
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M.O.A. for Pilocarpine
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Activates muscarinic receptors in ciliary muscle, increasing aqueous humor outflow
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Special Considerations
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Useful in patients with xerostomia due to radiation of head and neck and Sjogren's syndrome
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Adverse Effects of Pilocarpine
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Miosis, blurred vision (accommodative spasm)
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Interactions of Pilocarpine
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Additive effects with other cholinergic drugs, effects decreased by atropine and anticholinergic drugs
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Similar drugs to Pilocarpine
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cevimeline
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Pronunciation of Pralidoxime
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pral-i-DOX-ime
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Brand name of Pralidoxime
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Protopam TM
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Therapeutic Class of Pralidoxime
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Organophosphate antidote
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Pharmacolgoic Class of Pralidoxime
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Cholinesterase reactivator
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M.O.A. for Pralidoxime
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Binds phosphorus of organophosphate and breaks organophosphate bond with cholinesterase
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Clinical Use of Pralidoxime
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Treatment of organophosphate toxicity (reverse muscle weakness)
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Special Considerations of Pralidoxime
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Give as soon as possible after organophosphate exposure (before "aging" aging of organophosphate bond with cholinesterase)
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Adverse Effects of Pralidoxime
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When treating organophosphate poisoning it is difficult to differentiate the toxic effects of pralidoxime from those produced by atropine or organophosphate compounds
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Interactions of Pralidoxime
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When used with atropine, signs of atropinization occur earlier than when atropine is used alone.
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Similar Drugs to Pralidoxime
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none
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Pronunciation of Propranolol
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proe-PRAN-oh-lol
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Brand name of Propranolol
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Inderal TM
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Therapeutic Class of Propranolol
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Sympatholytic, antihypertensive
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Pharmacologic Class of Propranolol
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Nonselective adrenergic Beta receptor antagonist
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M.O.A. for Propranolol
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Competitvely blocks beta 1 and beta 2 receptors
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Clinical Use of Propranolol
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Angina, hypertension, post-myocardial infarction, cardiomyopathy, benign tremor, migraine prophylaxis, thyrotoxicosis
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Special Considerations for Propranolol
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Highly lipophilic (central nervous system effects)
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Adverse Effects of Propranolol
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Bronchoconstriction, inhibits glycogenolysis, nightmares and mood depression
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Interactions of Propranolol
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Additive hypotensive effect with nitrates and antihypertensive drugs, additive bradycardia with digoxin, decreases effects of dopamine and dobutamine
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Similar drugs to Propranolol
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nadolol, pindolol, timolol
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Pronunciation of pseudoephedrine
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soo-doe-e-FED-rin
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Trademark name of pseudoephedrine
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Sudafed TM
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Therapeutic Class of Pseudoephedrine
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Decongestant
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Pharmacologic Class of Pseudoephedrine
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Indirect- and direct-acting adrenergic receptor agonist
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M.O.A. for Pseudoephedrine
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Increases release of norephineephrine and directly activates adreneggic receprots, causing vasoconstrictoin and cardiac stimulation
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Clinical Use for Pseudoephedrine
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Nasal decongestant for allergic and viral rhinitis
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Special Considerations for Pseudoephedrine
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Urine acidification or alkalinization may increase or decrease excreation, respectively
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Adverse Effects
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Tachycardia
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Interactions of Pseudoephedrine
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Concurrent use with monoamine oxidase inhibitors may cause severe hypertension.
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Similar drugs to pseudoephedrine
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norepinephrine, PHENYLEPHRINE
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Pronunciation of Pyridostigmine
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peer-i-doe-STIG-meen
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Brand name of pyridostgmine
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Mestinon TM
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Therapeutic Class of pyridostigmine
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Antimyasthenic
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Pharmacologic Class of pyridostigmine
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Cholinesterase inhibitor, cholinergic agonist
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M.O.A. for pyridostigmine
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Reversibly inhibits cholinesterase
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Clinical use of pyridostigmine
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Treatment of myasthenia gravis
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Special Considerations for pyridostigmine
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Muscarinic effects blocked by atropine
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Adverse Effects of pyridostigmine
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Muscarinic effects (e.g., miosis, salivation)
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Interactions of pyridostigmine
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Prolongs effects of succinylcholine, effects reduced by atropine, antidepressants, phenothiazine drugs, quinidine, and other drugs with anticholinergic effects.
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Similiar drugs to pyridostigmine
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EDROPHONIUM, neostigmine, physostigmine
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What is the pronunciation of Rocuronium
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roe-cue-ROE-nee-um
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What is the brand name for Rocuronium
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Zemuron TM
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Therapeutic Class of Rocuronium
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Paralytic agent
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Pharmacologic Class of Rocuronium
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Nondepolarizing neuromuscular blocking agent
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M.O.A. for Rocurronium
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Competitively blocks nicotinic receptors in skeletal muscle
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Clinical Uses of Rocuronium
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Skeletal muscle relaxation for intubation, surgery, and electroconvulsive therapy
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Special Considerations for Rocuronium
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Effects reversed by neostigmine and edrophonium
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Adverse Effects of Rocuronium
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Respiratory muscle paralysis and apnea
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Interactions of Rocuronium
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Effects potentiated by anesthetics, calcium channel blockers, tetracycline, and aminoglycoside antibiotics
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Similar drugs
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atracurium, mivacurium, pancuronium, tubcurarine, vecuronium
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Pronunciation for Sildenafil
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sil-DEN-a-fil
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Brand name for sildenafil
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Viagra TM
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Therapeutic class for sildenafil
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Vasodilator
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Pharmacologic Class for sildenafil
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Phosphodiesterase inhibitor
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Clinical Use of Sildenafil
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Treatment of erectile dysfunction
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Special considerations for Sildenafil
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Concurrent use with organic nitrates can cause reflex tachycardia, angina, and death from myocardial ischemia
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Adverse effects of Sildenafil
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Headache, nasal congestion, back pain, visual disturbances
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Interactions of sildenafil
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Potentiates vasodilation produced by organic nitrates, serum levels increased by CYP3A4 inhibitors
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Similar drugs to Sildenafil
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tadalafil, vardenafil
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Pronunciation of Succinylcholine
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sux-sin-il-KOE-leen
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Brand name for Succinylcholine
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Anectine TM
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Therapeutic class of Succinylcholine
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Paralytic agent
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Pharmacologic class of Succinylcholine
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Depolarizing neuromuscular blocker
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M.O.A. for Succinylcholine
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Binds to nicotinic receptors, causing prolonged depolarization of skeletal muscle and paralysis.
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Clinical use of Succinylcholine
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Short-term skeletal muscle relazation for intubation and surgery
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Special considerations for using Succinylcholine
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Causes transient muscle fasciculation,effects are not reveresed by neostgmine or edrophonium.
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Adverse effects of Succinylcholine
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Respiratory muscle paralysis and apnea, especially in persons with rare atypical cholinesterase.
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Interacations of Succinylcholine
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Neuromuscular blockade enhanced by aminoglycoside antibiotics, clindamycin, amphotericin B, quinidine, and cholinesterase inhibitors.
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Pronunciation of Tamsulosin
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tam-soo-LOE-sin
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Brand Name of Tamsulosin
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Flomax TM
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Therapeutic Class of Tamsulosin
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Urologic agent
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Pharmacologic Class of Tamsulosin
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Uroselective adrenergic alpha-1 receptor antagonist
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M.O.A. of Tamsulosin
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Competitvely blocks alpha-1A receptors in prostrate
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Clinical Use of Tamsulosin
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Treatment of urinary outflow obstruction in men with prostatic hyperplasia.
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Special Considerations
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Not indicated for treatment of hypertension
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Adverse Effects of Tamsulosin
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Dizziness
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Interactions of Tamsulosin
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Cimetidine may increase blood levels and effects
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Similar Drugs to Tamsulosin
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alfuzosin, TERAZOSIN
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Pronunciation of Terzosin
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ter-AZ-oh-sin
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Brand Name of Terazosin
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Hytrin TM
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Therapeutic Class of Terazosin
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Antihypertensive agent
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Pharmacologic Class of Terazosin
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Selective adrenergic alpha-1 receptor antagonist
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M.O.A. for Terazosin
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Competitively blocks alpha-1 receptors
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Clinical use for terazosin
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Treatment of hypertension
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Special Considerations for using Terazosin
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Less selective for prostatic smooth muscle than tamsulosin and alfuzosin
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Adverse Effects of Terazosin
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Hypotension, "first-dose" syncope
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Interactions of Terazosin
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Additive hypotensive effect with diuretics and other antihypertensive drugs.
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Similar Drugs to Terazosin
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doxazosin, prazosion, TAMSULOSIN
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Pronunciation of Atenolol
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a-TEN-oh-lol
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What is the brand name of Atenolol?
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Tenormin TM
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What is the Therapeutic Class of Atenolol
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Sympatholytic/Antihypertensive
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What is the Pharmacologic Class of Atenolol?
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Selective adrenergic Beta 1 receptor antagonist
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M.O.A of Atenolol?
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Competitively blocks Beta 1 receptors
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Clinical Uses of Atenolol
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Angina, hypertension
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Special Considerations
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Less lipophilic, fewer central nervous sytem side effects
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Adverse Effects of Atenolol
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Bronchoconstriction with higher doses because of Beta 2 receptor blockade
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Interactions of Atenolol
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Additive hypotensive effect with nitrates and antihypertensive drugs/additve bradycardia with digoxin, decreases effects of dopamine and dobutamine
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Drugs similiar to Atenolol
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acebutolo, betaxolol, bisoprolol, ESMOLOL, metoprolol
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Pronunciation of Atropine
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AT-roe-peen
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What is the brand name of Atropine?
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Atro-Pen TM
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What is the Therapeutic Class of Atropine
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Anticholinergic agent
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What is the Parmacologic Class of Atropine
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Muscarinic receptor antagonist
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M.O.A. for Atropine
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Competitively blocks all muscarinic receptors
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Clinical Uses of Atropine
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Bradycardia and atrioventricular block, irritable bowel symptoms, anticholinesterase poisoning
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What are the Special considerations when using atropine?
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Can slow heart rate when first administered
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What are the adverse effects of atropine?
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Tachycardia, mydriasis and cycloplegia, warm, dry, flushed skin, delirium, and hallucinations
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Interactions of Atropine
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Additive anticholinergic effects with antihistamines (diphenhydramine) and tricyclic antidepressants (amitriptyline), slows absorbtion of other drugs by delaying gastic emptying
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Similiar drugs
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DICYCLOMINE, glycopyrrolate, hyoscyamine, IPRATROPIUM, oxybutynin, scopolamine, tolterodine
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Pronunciation of Dobutamine
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doe-BUE-ta-meen
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Brand name of Dobutamine
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Dobutrex TM
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Therapeutic Class of Dobutamine
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sympathomimetic, cardiac stimulant
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Pharmacologic Class of Dobutamine
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Selective Beta 1 adrenergic receptor agonist
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M.O.A of Dobutamine
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Activates Beta 1 > Beta 2 >> Alpha 1 receptors, increases cardiac contractility and cardiac output > heart rate
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Clincial Uses of Dobutamine
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Acute heart failure and cardiogenic shock
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Special Considerations of using Dobutamine
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Administered by Intravenous infusion
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Adverse effects of Dobutamine
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Tachycardia and arrhythmia
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Interactions
|
Synergistic effect on cardiac output with nitroprusside
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Similiar drugs to Dobutamine
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none
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Pronunciation of Edrophonium
|
ed-roe-FOE-nee-um
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Brand name of Edrophonium
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Tensilon TM
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Therapeutic Class of Edrophonium
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Diagnostic agent
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Pharmacologic Class of Edrophonium
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Cholinesterase inhibitor
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M.O.A. for Edrophonium
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Reversibly binds and inhibits cholinesterase
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Clinical Use of Edrophonium
|
Diagnosis of myasthenia gravis, differential diagnosis of myasthenic crisis and cholinergic crisis
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Special Considerations of using Edrophonium
|
Very short-acting after intravenous administration
|
|
|
|
Adverse Effects of Edrophonium
|
Muscarinic effects (e.g. miosis, salivation)
|
|
|
|
Interactions of Edrophonium
|
None usually significant
|
|
|
|
Similar drugs to Edrophonium
|
neostigmine, physostigmine, PYRIDOSTIGMINE
|
|
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|
Pronunciation of Epinephrine
|
e-pi-NEF-rin
|
|
|
|
What is the brand name of Epinephrine?
|
Adrenalin TM
|
|
|
|
What is the therapeutic class of epinephrine?
|
Sympathomimetic
|
|
|
|
What is the Pharmacologic class of epinephrine?
|
Nonselective adrenergic agonist.
|
|
|
|
M.O.A for Epinephrine
|
Activates alpha and beta receptors, increasing inositol triphosphate and cyclic adenosine monophosphate, alpha 1 - vasoconstriction and increased blood pressure, beta 1 - increased heart rate, conduction, and contractility, beta 2 - vasodilation and decreased diastolic blood pressure, bronchodilation
|
|
|
|
Clinical Uses of Epinephrine
|
Cardiac arrest, ventricular fibrillation, anaphylactic shcok, asthma, chronic obstructive pumonary disease
|
|
|
|
Adverse Effects of Epinephrine
|
Hypertension, tachycardia, ischemia, hyperglycemia
|
|
|
|
Interactions of Epinephrine
|
None usually significant
|
|
|
|
Similiar drugs to epinephrine
|
none
|
|
|
|
Pronunciation of Phenoxybenzamine
|
fen-ox-i-BENZ-a-meen
|
|
|
|
What is the brand name Phenoxybenzamine
|
Dibenzyline TM
|
|
|
|
Therapeutic class of Phenoxybenzamine
|
Vasodilator
|
|
|
|
Phrmacologic Class
|
Irreversible adrenergic alpha receptor antagonist
|
|
|
|
M.O.A. for Phenoxybenzamine
|
Blocks Alpha 1 > Alpha 2 receptors
|
|
|
|
Clinical Use for Phenoxybenzamine
|
Presurgical treatment of hypertension caused by pheochromocytoma
|
|
|
|
Special Considerations for using Phenoxybenzamine
|
Forms covalent bond with alpha receptor
|
|
|
|
Adverse Effects of Phenoxybenzamine
|
Postural hypotension
|
|
|
|
Interactions of Phenoxybenzamine
|
Hypotensive effect increased by beta-adrenergic blockers and calcium channel blockers
|
|
|
|
Similar drugs to Phenoxybenzamine
|
phentolamine
|
|
|
|
Pronunciation of Phentolamine
|
fen-TOE-la-meen
|
|
|
|
Brand name of Phentolamine
|
Regitine TM
|
|
|
|
Therapeutic Class of Phentolamine
|
Vasodilator
|
|
|
|
Pharmacologic Class of Phentolamine
|
Adrenergic alpha receptor antagonist
|
|
|
|
M.O.A. for Phentolamine
|
Competively blocks alpha 1 and alpha 2 receptors
|
|
|
|
Clinical Use of Phentolamine
|
Counteract vasoconstriction caused by accidental injection or extravasation of vasoconstrictors
|
|
|
|
Special Considerations of Phentolamine
|
Parenteral administration only
|
|
|
|
Adverse Effects of Phentolamine
|
Hypotension
|
|
|
|
Interactions of Phentolamine
|
Severe hypotension if give with epinephrine, blocks effects of alpha-adrenergic agonists
|
|
|
|
Similiar drugs
|
phenoxybenzamine
|
|
|
|
Pronunciation of Phenylephrine
|
fen-il-EF-rin
|
|
|
|
Trademark
|
Neo-Synephrine TM
|
|
|
|
Therapeutic Class of Phenylephrine
|
Vasoconstrictor
|
|
|
|
Pharmacologic Class of Phenylephrine
|
Selective adrenergic alpha 1 receptor agonist
|
|
|
|
M.O.A. of Phenylephrine
|
Activates alpha 1 receptors, increasing inositol triphospate and causing contraction of vascular smooth muscle
|
|
|
|
Clinical Use
|
Nasal and ocular decongestant
|
|
|
|
Special Considerations of Phenylephrine
|
Occular administration causes mydriasis with cycloplegia (paralysis of accomodation)
|
|
|
|
Adverse Effects of Phenylephrine
|
Rebound nasal congestion
|
|
|
|
Interactions of Phenylephrine
|
May cause severe hypertension if given with monoamine oxidase inhibitors
|
|
|
|
Similiar Drugs
|
norepinephrine, PSEUDOEPHEDRINE
|
|
|
|
Pronunciation of Pilocarpine
|
pye-loe-CAR-peen
|
|
|
|
Brand name of Pilocarpine
|
Salagen TM
|
|
|
|
Therapeutic Class of Pilocarpine
|
Antiglaucoma agent, sialagogue
|
|
|
|
Pharmacologic Class of Pilocarpine
|
Muscarinic receptor agonist
|
|
|
|
M.O.A. for Pilocarpine
|
Activates muscarinic receptors in ciliary muscle, increasing aqueous humor outflow
|
|
|
|
Special Considerations
|
Useful in patients with xerostomia due to radiation of head and neck and Sjogren's syndrome
|
|
|
|
Adverse Effects of Pilocarpine
|
Miosis, blurred vision (accommodative spasm)
|
|
|
|
Interactions of Pilocarpine
|
Additive effects with other cholinergic drugs, effects decreased by atropine and anticholinergic drugs
|
|
|
|
Similar drugs to Pilocarpine
|
cevimeline
|
|
|
|
Pronunciation of Pralidoxime
|
pral-i-DOX-ime
|
|
|
|
Brand name of Pralidoxime
|
Protopam TM
|
|
|
|
Therapeutic Class of Pralidoxime
|
Organophosphate antidote
|
|
|
|
Pharmacolgoic Class of Pralidoxime
|
Cholinesterase reactivator
|
|
|
|
M.O.A. for Pralidoxime
|
Binds phosphorus of organophosphate and breaks organophosphate bond with cholinesterase
|
|
|
|
Clinical Use of Pralidoxime
|
Treatment of organophosphate toxicity (reverse muscle weakness)
|
|
|
|
Special Considerations of Pralidoxime
|
Give as soon as possible after organophosphate exposure (before "aging" aging of organophosphate bond with cholinesterase)
|
|
|
|
Adverse Effects of Pralidoxime
|
When treating organophosphate poisoning it is difficult to differentiate the toxic effects of pralidoxime from those produced by atropine or organophosphate compounds
|
|
|
|
Interactions of Pralidoxime
|
When used with atropine, signs of atropinization occur earlier than when atropine is used alone.
|
|
|
|
Similar Drugs to Pralidoxime
|
none
|
|
|
|
Pronunciation of Propranolol
|
proe-PRAN-oh-lol
|
|
|
|
Brand name of Propranolol
|
Inderal TM
|
|
|
|
Therapeutic Class of Propranolol
|
Sympatholytic, antihypertensive
|
|
|
|
Pharmacologic Class of Propranolol
|
Nonselective adrenergic Beta receptor antagonist
|
|
|
|
M.O.A. for Propranolol
|
Competitvely blocks beta 1 and beta 2 receptors
|
|
|
|
Clinical Use of Propranolol
|
Angina, hypertension, post-myocardial infarction, cardiomyopathy, benign tremor, migraine prophylaxis, thyrotoxicosis
|
|
|
|
Special Considerations for Propranolol
|
Highly lipophilic (central nervous system effects)
|
|
|
|
Adverse Effects of Propranolol
|
Bronchoconstriction, inhibits glycogenolysis, nightmares and mood depression
|
|
|
|
Interactions of Propranolol
|
Additive hypotensive effect with nitrates and antihypertensive drugs, additive bradycardia with digoxin, decreases effects of dopamine and dobutamine
|
|
|
|
Similar drugs to Propranolol
|
nadolol, pindolol, timolol
|
|
|
|
Pronunciation of pseudoephedrine
|
soo-doe-e-FED-rin
|
|
|
|
Trademark name of pseudoephedrine
|
Sudafed TM
|
|
|
|
Therapeutic Class of Pseudoephedrine
|
Decongestant
|
|
|
|
Pharmacologic Class of Pseudoephedrine
|
Indirect- and direct-acting adrenergic receptor agonist
|
|
|
|
M.O.A. for Pseudoephedrine
|
Increases release of norephineephrine and directly activates adreneggic receprots, causing vasoconstrictoin and cardiac stimulation
|
|
|
|
Clinical Use for Pseudoephedrine
|
Nasal decongestant for allergic and viral rhinitis
|
|
|
|
Special Considerations for Pseudoephedrine
|
Urine acidification or alkalinization may increase or decrease excreation, respectively
|
|
|
|
Adverse Effects
|
Tachycardia
|
|
|
|
Interactions of Pseudoephedrine
|
Concurrent use with monoamine oxidase inhibitors may cause severe hypertension.
|
|
|
|
Similar drugs to pseudoephedrine
|
norepinephrine, PHENYLEPHRINE
|
|
|
|
Pronunciation of Pyridostigmine
|
peer-i-doe-STIG-meen
|
|
|
|
Brand name of pyridostgmine
|
Mestinon TM
|
|
|
|
Therapeutic Class of pyridostigmine
|
Antimyasthenic
|
|
|
|
Pharmacologic Class of pyridostigmine
|
Cholinesterase inhibitor, cholinergic agonist
|
|
|
|
M.O.A. for pyridostigmine
|
Reversibly inhibits cholinesterase
|
|
|
|
Clinical use of pyridostigmine
|
Treatment of myasthenia gravis
|
|
|
|
Special Considerations for pyridostigmine
|
Muscarinic effects blocked by atropine
|
|
|
|
Adverse Effects of pyridostigmine
|
Muscarinic effects (e.g., miosis, salivation)
|
|
|
|
Interactions of pyridostigmine
|
Prolongs effects of succinylcholine, effects reduced by atropine, antidepressants, phenothiazine drugs, quinidine, and other drugs with anticholinergic effects.
|
|
|
|
Similiar drugs to pyridostigmine
|
EDROPHONIUM, neostigmine, physostigmine
|
|
|
|
What is the pronunciation of Rocuronium
|
roe-cue-ROE-nee-um
|
|
|
|
What is the brand name for Rocuronium
|
Zemuron TM
|
|
|
|
Therapeutic Class of Rocuronium
|
Paralytic agent
|
|
|
|
Pharmacologic Class of Rocuronium
|
Nondepolarizing neuromuscular blocking agent
|
|
|
|
M.O.A. for Rocurronium
|
Competitively blocks nicotinic receptors in skeletal muscle
|
|
|
|
Clinical Uses of Rocuronium
|
Skeletal muscle relaxation for intubation, surgery, and electroconvulsive therapy
|
|
|
|
Special Considerations for Rocuronium
|
Effects reversed by neostigmine and edrophonium
|
|
|
|
Adverse Effects of Rocuronium
|
Respiratory muscle paralysis and apnea
|
|
|
|
Interactions of Rocuronium
|
Effects potentiated by anesthetics, calcium channel blockers, tetracycline, and aminoglycoside antibiotics
|
|
|
|
Similar drugs
|
atracurium, mivacurium, pancuronium, tubcurarine, vecuronium
|
|
|
|
Pronunciation for Sildenafil
|
sil-DEN-a-fil
|
|
|
|
Brand name for sildenafil
|
Viagra TM
|
|
|
|
Therapeutic class for sildenafil
|
Vasodilator
|
|
|
|
Pharmacologic Class for sildenafil
|
Phosphodiesterase inhibitor
|
|
|
|
M.O.A. of Sildenafil
|
Inhibits type 5 phosphodiesterase and degradation of cyclic guanosine monophosphate, thereby increasng vasodilation in corpus cavernosum evoked by acetylcholine released from sacral parsympathetic neurons
|
|
|
|
Clinical Use of Sildenafil
|
Treatment of erectile dysfunction
|
|
|
|
Special considerations for Sildenafil
|
Concurrent use with organic nitrates can cause reflex tachycardia, angina, and death from myocardial ischemia
|
|
|
|
Adverse effects of Sildenafil
|
Headache, nasal congestion, back pain, visual disturbances
|
|
|
|
Interactions of sildenafil
|
Potentiates vasodilation produced by organic nitrates, serum levels increased by CYP3A4 inhibitors
|
|
|
|
Similar drugs to Sildenafil
|
tadalafil, vardenafil
|
|
|
|
Pronunciation of Succinylcholine
|
sux-sin-il-KOE-leen
|
|
|
|
Brand name for Succinylcholine
|
Anectine TM
|
|
|
|
Therapeutic class of Succinylcholine
|
Paralytic agent
|
|
|
|
Pharmacologic class of Succinylcholine
|
Depolarizing neuromuscular blocker
|
|
|
|
M.O.A. for Succinylcholine
|
Binds to nicotinic receptors, causing prolonged depolarization of skeletal muscle and paralysis.
|
|
|
|
Clinical use of Succinylcholine
|
Short-term skeletal muscle relazation for intubation and surgery
|
|
|
|
Special considerations for using Succinylcholine
|
Causes transient muscle fasciculation,effects are not reveresed by neostgmine or edrophonium.
|
|
|
|
Adverse effects of Succinylcholine
|
Respiratory muscle paralysis and apnea, especially in persons with rare atypical cholinesterase.
|
|
|
|
Interacations of Succinylcholine
|
Neuromuscular blockade enhanced by aminoglycoside antibiotics, clindamycin, amphotericin B, quinidine, and cholinesterase inhibitors.
|
|
|
|
Pronunciation of Tamsulosin
|
tam-soo-LOE-sin
|
|
|
|
Brand Name of Tamsulosin
|
Flomax TM
|
|
|
|
Therapeutic Class of Tamsulosin
|
Urologic agent
|
|
|
|
Pharmacologic Class of Tamsulosin
|
Uroselective adrenergic alpha-1 receptor antagonist
|
|
|
|
M.O.A. of Tamsulosin
|
Competitvely blocks alpha-1A receptors in prostrate
|
|
|
|
Clinical Use of Tamsulosin
|
Treatment of urinary outflow obstruction in men with prostatic hyperplasia.
|
|
|
|
Special Considerations
|
Not indicated for treatment of hypertension
|
|
|
|
Adverse Effects of Tamsulosin
|
Dizziness
|
|
|
|
Interactions of Tamsulosin
|
Cimetidine may increase blood levels and effects
|
|
|
|
Similar Drugs to Tamsulosin
|
alfuzosin, TERAZOSIN
|
|
|
|
Pronunciation of Terzosin
|
ter-AZ-oh-sin
|
|
|
|
Brand Name of Terazosin
|
Hytrin TM
|
|
|
|
Therapeutic Class of Terazosin
|
Antihypertensive agent
|
|
|
|
Pharmacologic Class of Terazosin
|
Selective adrenergic alpha-1 receptor antagonist
|
|
|
|
M.O.A. for Terazosin
|
Competitively blocks alpha-1 receptors
|
|
|
|
Clinical use for terazosin
|
Treatment of hypertension
|
|
|
|
Special Considerations for using Terazosin
|
Less selective for prostatic smooth muscle than tamsulosin and alfuzosin
|
|
|
|
Adverse Effects of Terazosin
|
Hypotension, "first-dose" syncope
|
|
|
|
Interactions of Terazosin
|
Additive hypotensive effect with diuretics and other antihypertensive drugs.
|
|
|
|
Similar Drugs to Terazosin
|
doxazosin, prazosion, TAMSULOSIN
|
|
