Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/352

Click to flip

352 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
Pronunciation of Atenolol
a-TEN-oh-lol
What is the brand name of Atenolol?
Tenormin TM
What is the Therapeutic Class of Atenolol
Sympatholytic/Antihypertensive
What is the Pharmacologic Class of Atenolol?
Selective adrenergic Beta 1 receptor antagonist
M.O.A of Atenolol?
Competitively blocks Beta 1 receptors
Clinical Uses of Atenolol
Angina, hypertension
Special Considerations of Atenolol
Less lipophilic, fewer central nervous sytem side effects
None
Adverse Effects of Atenolol
Bronchoconstriction with higher doses because of Beta 2 receptor blockade
Interactions of Atenolol
Additive hypotensive effect with nitrates and antihypertensive drugs/additve bradycardia with digoxin, decreases effects of dopamine and dobutamine
Drugs similiar to Atenolol
acebutolo, betaxolol, bisoprolol, ESMOLOL, metoprolol
Pronunciation of Atropine
AT-roe-peen
What is the brand name of Atropine?
Atro-Pen TM
What is the Therapeutic Class of Atropine
Anticholinergic agent
What is the Parmacologic Class of Atropine
Muscarinic receptor antagonist
M.O.A. for Atropine
Competitively blocks all muscarinic receptors
Clinical Uses of Atropine
Bradycardia and atrioventricular block, irritable bowel symptoms, anticholinesterase poisoning
What are the Special considerations when using atropine?
Can slow heart rate when first administered
What are the adverse effects of atropine?
Tachycardia, mydriasis and cycloplegia, warm, dry, flushed skin, delirium, and hallucinations
Interactions of Atropine
Additive anticholinergic effects with antihistamines (diphenhydramine) and tricyclic antidepressants (amitriptyline), slows absorbtion of other drugs by delaying gastic emptying
Similiar drugs
DICYCLOMINE, glycopyrrolate, hyoscyamine, IPRATROPIUM, oxybutynin, scopolamine, tolterodine
Pronunciation of Dobutamine
doe-BUE-ta-meen
Brand name of Dobutamine
Dobutrex TM
Therapeutic Class of Dobutamine
sympathomimetic, cardiac stimulant
Pharmacologic Class of Dobutamine
Selective Beta 1 adrenergic receptor agonist
M.O.A of Dobutamine
Activates Beta 1 > Beta 2 >> Alpha 1 receptors, increases cardiac contractility and cardiac output > heart rate
Clincial Uses of Dobutamine
Acute heart failure and cardiogenic shock
Special Considerations of using Dobutamine
Administered by Intravenous infusion
Adverse effects of Dobutamine
Tachycardia and arrhythmia
Interactions
Synergistic effect on cardiac output with nitroprusside
Similiar drugs to Dobutamine
none
Pronunciation of Edrophonium
ed-roe-FOE-nee-um
Brand name of Edrophonium
Tensilon TM
Therapeutic Class of Edrophonium
Diagnostic agent
Pharmacologic Class of Edrophonium
Cholinesterase inhibitor
M.O.A. for Edrophonium
Reversibly binds and inhibits cholinesterase
Clinical Use of Edrophonium
Diagnosis of myasthenia gravis, differential diagnosis of myasthenic crisis and cholinergic crisis
Special Considerations of using Edrophonium
Very short-acting after intravenous administration
Adverse Effects of Edrophonium
Muscarinic effects (e.g. miosis, salivation)
Interactions of Edrophonium
None usually significant
Similar drugs to Edrophonium
neostigmine, physostigmine, PYRIDOSTIGMINE
Pronunciation of Epinephrine
e-pi-NEF-rin
What is the brand name of Epinephrine?
Adrenalin TM
What is the therapeutic class of epinephrine?
Sympathomimetic
What is the Pharmacologic class of epinephrine?
Nonselective adrenergic agonist.
M.O.A for Epinephrine
Activates alpha and beta receptors, increasing inositol triphosphate and cyclic adenosine monophosphate, alpha 1 - vasoconstriction and increased blood pressure, beta 1 - increased heart rate, conduction, and contractility, beta 2 - vasodilation and decreased diastolic blood pressure, bronchodilation
Clinical Uses of Epinephrine
Cardiac arrest, ventricular fibrillation, anaphylactic shcok, asthma, chronic obstructive pumonary disease
Adverse Effects of Epinephrine
Hypertension, tachycardia, ischemia, hyperglycemia
Interactions of Epinephrine
None usually significant
Similiar drugs to epinephrine
none
Pronunciation of Phenoxybenzamine
fen-ox-i-BENZ-a-meen
What is the brand name Phenoxybenzamine
Dibenzyline TM
Therapeutic class of Phenoxybenzamine
Vasodilator
Phrmacologic Class
Irreversible adrenergic alpha receptor antagonist
M.O.A. for Phenoxybenzamine
Blocks Alpha 1 > Alpha 2 receptors
Clinical Use for Phenoxybenzamine
Presurgical treatment of hypertension caused by pheochromocytoma
Special Considerations for using Phenoxybenzamine
Forms covalent bond with alpha receptor
Adverse Effects of Phenoxybenzamine
Postural hypotension
Interactions of Phenoxybenzamine
Hypotensive effect increased by beta-adrenergic blockers and calcium channel blockers
Similar drugs to Phenoxybenzamine
phentolamine
Pronunciation of Phentolamine
fen-TOE-la-meen
Brand name of Phentolamine
Regitine TM
Therapeutic Class of Phentolamine
Vasodilator
Pharmacologic Class of Phentolamine
Adrenergic alpha receptor antagonist
M.O.A. for Phentolamine
Competively blocks alpha 1 and alpha 2 receptors
Clinical Use of Phentolamine
Counteract vasoconstriction caused by accidental injection or extravasation of vasoconstrictors
Special Considerations of Phentolamine
Parenteral administration only
Adverse Effects of Phentolamine
Hypotension
Interactions of Phentolamine
Severe hypotension if give with epinephrine, blocks effects of alpha-adrenergic agonists
Pronunciation of Phenylephrine
fen-il-EF-rin
Trademark
Neo-Synephrine TM
Therapeutic Class of Phenylephrine
Vasoconstrictor
Pharmacologic Class of Phenylephrine
Selective adrenergic alpha 1 receptor agonist
M.O.A. of Phenylephrine
Activates alpha 1 receptors, increasing inositol triphospate and causing contraction of vascular smooth muscle
Clinical Use
Nasal and ocular decongestant
Special Considerations of Phenylephrine
Occular administration causes mydriasis with cycloplegia (paralysis of accomodation)
Adverse Effects of Phenylephrine
Rebound nasal congestion
Interactions of Phenylephrine
May cause severe hypertension if given with monoamine oxidase inhibitors
Similiar Drugs
norepinephrine, PSEUDOEPHEDRINE
Pronunciation of Pilocarpine
pye-loe-CAR-peen
Brand name of Pilocarpine
Salagen TM
Therapeutic Class of Pilocarpine
Antiglaucoma agent, sialagogue
Pharmacologic Class of Pilocarpine
Muscarinic receptor agonist
M.O.A. for Pilocarpine
Activates muscarinic receptors in ciliary muscle, increasing aqueous humor outflow
Special Considerations
Useful in patients with xerostomia due to radiation of head and neck and Sjogren's syndrome
Adverse Effects of Pilocarpine
Miosis, blurred vision (accommodative spasm)
Interactions of Pilocarpine
Additive effects with other cholinergic drugs, effects decreased by atropine and anticholinergic drugs
Similar drugs to Pilocarpine
cevimeline
Pronunciation of Pralidoxime
pral-i-DOX-ime
Brand name of Pralidoxime
Protopam TM
Therapeutic Class of Pralidoxime
Organophosphate antidote
Pharmacolgoic Class of Pralidoxime
Cholinesterase reactivator
M.O.A. for Pralidoxime
Binds phosphorus of organophosphate and breaks organophosphate bond with cholinesterase
Clinical Use of Pralidoxime
Treatment of organophosphate toxicity (reverse muscle weakness)
Special Considerations of Pralidoxime
Give as soon as possible after organophosphate exposure (before "aging" aging of organophosphate bond with cholinesterase)
Adverse Effects of Pralidoxime
When treating organophosphate poisoning it is difficult to differentiate the toxic effects of pralidoxime from those produced by atropine or organophosphate compounds
Interactions of Pralidoxime
When used with atropine, signs of atropinization occur earlier than when atropine is used alone.
Similar Drugs to Pralidoxime
none
Pronunciation of Propranolol
proe-PRAN-oh-lol
Brand name of Propranolol
Inderal TM
Therapeutic Class of Propranolol
Sympatholytic, antihypertensive
Pharmacologic Class of Propranolol
Nonselective adrenergic Beta receptor antagonist
M.O.A. for Propranolol
Competitvely blocks beta 1 and beta 2 receptors
Clinical Use of Propranolol
Angina, hypertension, post-myocardial infarction, cardiomyopathy, benign tremor, migraine prophylaxis, thyrotoxicosis
Special Considerations for Propranolol
Highly lipophilic (central nervous system effects)
Adverse Effects of Propranolol
Bronchoconstriction, inhibits glycogenolysis, nightmares and mood depression
Interactions of Propranolol
Additive hypotensive effect with nitrates and antihypertensive drugs, additive bradycardia with digoxin, decreases effects of dopamine and dobutamine
Similar drugs to Propranolol
nadolol, pindolol, timolol
Pronunciation of pseudoephedrine
soo-doe-e-FED-rin
Trademark name of pseudoephedrine
Sudafed TM
Therapeutic Class of Pseudoephedrine
Decongestant
Pharmacologic Class of Pseudoephedrine
Indirect- and direct-acting adrenergic receptor agonist
M.O.A. for Pseudoephedrine
Increases release of norephineephrine and directly activates adreneggic receprots, causing vasoconstrictoin and cardiac stimulation
Clinical Use for Pseudoephedrine
Nasal decongestant for allergic and viral rhinitis
Special Considerations for Pseudoephedrine
Urine acidification or alkalinization may increase or decrease excreation, respectively
Adverse Effects
Tachycardia
Interactions of Pseudoephedrine
Concurrent use with monoamine oxidase inhibitors may cause severe hypertension.
Similar drugs to pseudoephedrine
norepinephrine, PHENYLEPHRINE
Pronunciation of Pyridostigmine
peer-i-doe-STIG-meen
Brand name of pyridostgmine
Mestinon TM
Therapeutic Class of pyridostigmine
Antimyasthenic
Pharmacologic Class of pyridostigmine
Cholinesterase inhibitor, cholinergic agonist
M.O.A. for pyridostigmine
Reversibly inhibits cholinesterase
Clinical use of pyridostigmine
Treatment of myasthenia gravis
Special Considerations for pyridostigmine
Muscarinic effects blocked by atropine
Adverse Effects of pyridostigmine
Muscarinic effects (e.g., miosis, salivation)
Interactions of pyridostigmine
Prolongs effects of succinylcholine, effects reduced by atropine, antidepressants, phenothiazine drugs, quinidine, and other drugs with anticholinergic effects.
Similiar drugs to pyridostigmine
EDROPHONIUM, neostigmine, physostigmine
What is the pronunciation of Rocuronium
roe-cue-ROE-nee-um
What is the brand name for Rocuronium
Zemuron TM
Therapeutic Class of Rocuronium
Paralytic agent
Pharmacologic Class of Rocuronium
Nondepolarizing neuromuscular blocking agent
M.O.A. for Rocurronium
Competitively blocks nicotinic receptors in skeletal muscle
Clinical Uses of Rocuronium
Skeletal muscle relaxation for intubation, surgery, and electroconvulsive therapy
Special Considerations for Rocuronium
Effects reversed by neostigmine and edrophonium
Adverse Effects of Rocuronium
Respiratory muscle paralysis and apnea
Interactions of Rocuronium
Effects potentiated by anesthetics, calcium channel blockers, tetracycline, and aminoglycoside antibiotics
Similar drugs
atracurium, mivacurium, pancuronium, tubcurarine, vecuronium
Pronunciation for Sildenafil
sil-DEN-a-fil
Brand name for sildenafil
Viagra TM
Therapeutic class for sildenafil
Vasodilator
Pharmacologic Class for sildenafil
Phosphodiesterase inhibitor
Clinical Use of Sildenafil
Treatment of erectile dysfunction
Special considerations for Sildenafil
Concurrent use with organic nitrates can cause reflex tachycardia, angina, and death from myocardial ischemia
Adverse effects of Sildenafil
Headache, nasal congestion, back pain, visual disturbances
Interactions of sildenafil
Potentiates vasodilation produced by organic nitrates, serum levels increased by CYP3A4 inhibitors
Similar drugs to Sildenafil
tadalafil, vardenafil
Pronunciation of Succinylcholine
sux-sin-il-KOE-leen
Brand name for Succinylcholine
Anectine TM
Therapeutic class of Succinylcholine
Paralytic agent
Pharmacologic class of Succinylcholine
Depolarizing neuromuscular blocker
M.O.A. for Succinylcholine
Binds to nicotinic receptors, causing prolonged depolarization of skeletal muscle and paralysis.
Clinical use of Succinylcholine
Short-term skeletal muscle relazation for intubation and surgery
Special considerations for using Succinylcholine
Causes transient muscle fasciculation,effects are not reveresed by neostgmine or edrophonium.
Adverse effects of Succinylcholine
Respiratory muscle paralysis and apnea, especially in persons with rare atypical cholinesterase.
Interacations of Succinylcholine
Neuromuscular blockade enhanced by aminoglycoside antibiotics, clindamycin, amphotericin B, quinidine, and cholinesterase inhibitors.
Pronunciation of Tamsulosin
tam-soo-LOE-sin
Brand Name of Tamsulosin
Flomax TM
Therapeutic Class of Tamsulosin
Urologic agent
Pharmacologic Class of Tamsulosin
Uroselective adrenergic alpha-1 receptor antagonist
M.O.A. of Tamsulosin
Competitvely blocks alpha-1A receptors in prostrate
Clinical Use of Tamsulosin
Treatment of urinary outflow obstruction in men with prostatic hyperplasia.
Special Considerations
Not indicated for treatment of hypertension
Adverse Effects of Tamsulosin
Dizziness
Interactions of Tamsulosin
Cimetidine may increase blood levels and effects
Similar Drugs to Tamsulosin
alfuzosin, TERAZOSIN
Pronunciation of Terzosin
ter-AZ-oh-sin
Brand Name of Terazosin
Hytrin TM
Therapeutic Class of Terazosin
Antihypertensive agent
Pharmacologic Class of Terazosin
Selective adrenergic alpha-1 receptor antagonist
M.O.A. for Terazosin
Competitively blocks alpha-1 receptors
Clinical use for terazosin
Treatment of hypertension
Special Considerations for using Terazosin
Less selective for prostatic smooth muscle than tamsulosin and alfuzosin
Adverse Effects of Terazosin
Hypotension, "first-dose" syncope
Interactions of Terazosin
Additive hypotensive effect with diuretics and other antihypertensive drugs.
Similar Drugs to Terazosin
doxazosin, prazosion, TAMSULOSIN
Pronunciation of Atenolol
a-TEN-oh-lol
What is the brand name of Atenolol?
Tenormin TM
What is the Therapeutic Class of Atenolol
Sympatholytic/Antihypertensive
What is the Pharmacologic Class of Atenolol?
Selective adrenergic Beta 1 receptor antagonist
M.O.A of Atenolol?
Competitively blocks Beta 1 receptors
Clinical Uses of Atenolol
Angina, hypertension
Special Considerations
Less lipophilic, fewer central nervous sytem side effects
Adverse Effects of Atenolol
Bronchoconstriction with higher doses because of Beta 2 receptor blockade
Interactions of Atenolol
Additive hypotensive effect with nitrates and antihypertensive drugs/additve bradycardia with digoxin, decreases effects of dopamine and dobutamine
Drugs similiar to Atenolol
acebutolo, betaxolol, bisoprolol, ESMOLOL, metoprolol
Pronunciation of Atropine
AT-roe-peen
What is the brand name of Atropine?
Atro-Pen TM
What is the Therapeutic Class of Atropine
Anticholinergic agent
What is the Parmacologic Class of Atropine
Muscarinic receptor antagonist
M.O.A. for Atropine
Competitively blocks all muscarinic receptors
Clinical Uses of Atropine
Bradycardia and atrioventricular block, irritable bowel symptoms, anticholinesterase poisoning
What are the Special considerations when using atropine?
Can slow heart rate when first administered
What are the adverse effects of atropine?
Tachycardia, mydriasis and cycloplegia, warm, dry, flushed skin, delirium, and hallucinations
Interactions of Atropine
Additive anticholinergic effects with antihistamines (diphenhydramine) and tricyclic antidepressants (amitriptyline), slows absorbtion of other drugs by delaying gastic emptying
Similiar drugs
DICYCLOMINE, glycopyrrolate, hyoscyamine, IPRATROPIUM, oxybutynin, scopolamine, tolterodine
Pronunciation of Dobutamine
doe-BUE-ta-meen
Brand name of Dobutamine
Dobutrex TM
Therapeutic Class of Dobutamine
sympathomimetic, cardiac stimulant
Pharmacologic Class of Dobutamine
Selective Beta 1 adrenergic receptor agonist
M.O.A of Dobutamine
Activates Beta 1 > Beta 2 >> Alpha 1 receptors, increases cardiac contractility and cardiac output > heart rate
Clincial Uses of Dobutamine
Acute heart failure and cardiogenic shock
Special Considerations of using Dobutamine
Administered by Intravenous infusion
Adverse effects of Dobutamine
Tachycardia and arrhythmia
Interactions
Synergistic effect on cardiac output with nitroprusside
Similiar drugs to Dobutamine
none
Pronunciation of Edrophonium
ed-roe-FOE-nee-um
Brand name of Edrophonium
Tensilon TM
Therapeutic Class of Edrophonium
Diagnostic agent
Pharmacologic Class of Edrophonium
Cholinesterase inhibitor
M.O.A. for Edrophonium
Reversibly binds and inhibits cholinesterase
Clinical Use of Edrophonium
Diagnosis of myasthenia gravis, differential diagnosis of myasthenic crisis and cholinergic crisis
Special Considerations of using Edrophonium
Very short-acting after intravenous administration
Adverse Effects of Edrophonium
Muscarinic effects (e.g. miosis, salivation)
Interactions of Edrophonium
None usually significant
Similar drugs to Edrophonium
neostigmine, physostigmine, PYRIDOSTIGMINE
Pronunciation of Epinephrine
e-pi-NEF-rin
What is the brand name of Epinephrine?
Adrenalin TM
What is the therapeutic class of epinephrine?
Sympathomimetic
What is the Pharmacologic class of epinephrine?
Nonselective adrenergic agonist.
M.O.A for Epinephrine
Activates alpha and beta receptors, increasing inositol triphosphate and cyclic adenosine monophosphate, alpha 1 - vasoconstriction and increased blood pressure, beta 1 - increased heart rate, conduction, and contractility, beta 2 - vasodilation and decreased diastolic blood pressure, bronchodilation
Clinical Uses of Epinephrine
Cardiac arrest, ventricular fibrillation, anaphylactic shcok, asthma, chronic obstructive pumonary disease
Adverse Effects of Epinephrine
Hypertension, tachycardia, ischemia, hyperglycemia
Interactions of Epinephrine
None usually significant
Similiar drugs to epinephrine
none
Pronunciation of Phenoxybenzamine
fen-ox-i-BENZ-a-meen
What is the brand name Phenoxybenzamine
Dibenzyline TM
Therapeutic class of Phenoxybenzamine
Vasodilator
Phrmacologic Class
Irreversible adrenergic alpha receptor antagonist
M.O.A. for Phenoxybenzamine
Blocks Alpha 1 > Alpha 2 receptors
Clinical Use for Phenoxybenzamine
Presurgical treatment of hypertension caused by pheochromocytoma
Special Considerations for using Phenoxybenzamine
Forms covalent bond with alpha receptor
Adverse Effects of Phenoxybenzamine
Postural hypotension
Interactions of Phenoxybenzamine
Hypotensive effect increased by beta-adrenergic blockers and calcium channel blockers
Similar drugs to Phenoxybenzamine
phentolamine
Pronunciation of Phentolamine
fen-TOE-la-meen
Brand name of Phentolamine
Regitine TM
Therapeutic Class of Phentolamine
Vasodilator
Pharmacologic Class of Phentolamine
Adrenergic alpha receptor antagonist
M.O.A. for Phentolamine
Competively blocks alpha 1 and alpha 2 receptors
Clinical Use of Phentolamine
Counteract vasoconstriction caused by accidental injection or extravasation of vasoconstrictors
Special Considerations of Phentolamine
Parenteral administration only
Adverse Effects of Phentolamine
Hypotension
Interactions of Phentolamine
Severe hypotension if give with epinephrine, blocks effects of alpha-adrenergic agonists
Similiar drugs
phenoxybenzamine
Pronunciation of Phenylephrine
fen-il-EF-rin
Trademark
Neo-Synephrine TM
Therapeutic Class of Phenylephrine
Vasoconstrictor
Pharmacologic Class of Phenylephrine
Selective adrenergic alpha 1 receptor agonist
M.O.A. of Phenylephrine
Activates alpha 1 receptors, increasing inositol triphospate and causing contraction of vascular smooth muscle
Clinical Use
Nasal and ocular decongestant
Special Considerations of Phenylephrine
Occular administration causes mydriasis with cycloplegia (paralysis of accomodation)
Adverse Effects of Phenylephrine
Rebound nasal congestion
Interactions of Phenylephrine
May cause severe hypertension if given with monoamine oxidase inhibitors
Similiar Drugs
norepinephrine, PSEUDOEPHEDRINE
Pronunciation of Pilocarpine
pye-loe-CAR-peen
Brand name of Pilocarpine
Salagen TM
Therapeutic Class of Pilocarpine
Antiglaucoma agent, sialagogue
Pharmacologic Class of Pilocarpine
Muscarinic receptor agonist
M.O.A. for Pilocarpine
Activates muscarinic receptors in ciliary muscle, increasing aqueous humor outflow
Special Considerations
Useful in patients with xerostomia due to radiation of head and neck and Sjogren's syndrome
Adverse Effects of Pilocarpine
Miosis, blurred vision (accommodative spasm)
Interactions of Pilocarpine
Additive effects with other cholinergic drugs, effects decreased by atropine and anticholinergic drugs
Similar drugs to Pilocarpine
cevimeline
Pronunciation of Pralidoxime
pral-i-DOX-ime
Brand name of Pralidoxime
Protopam TM
Therapeutic Class of Pralidoxime
Organophosphate antidote
Pharmacolgoic Class of Pralidoxime
Cholinesterase reactivator
M.O.A. for Pralidoxime
Binds phosphorus of organophosphate and breaks organophosphate bond with cholinesterase
Clinical Use of Pralidoxime
Treatment of organophosphate toxicity (reverse muscle weakness)
Special Considerations of Pralidoxime
Give as soon as possible after organophosphate exposure (before "aging" aging of organophosphate bond with cholinesterase)
Adverse Effects of Pralidoxime
When treating organophosphate poisoning it is difficult to differentiate the toxic effects of pralidoxime from those produced by atropine or organophosphate compounds
Interactions of Pralidoxime
When used with atropine, signs of atropinization occur earlier than when atropine is used alone.
Similar Drugs to Pralidoxime
none
Pronunciation of Propranolol
proe-PRAN-oh-lol
Brand name of Propranolol
Inderal TM
Therapeutic Class of Propranolol
Sympatholytic, antihypertensive
Pharmacologic Class of Propranolol
Nonselective adrenergic Beta receptor antagonist
M.O.A. for Propranolol
Competitvely blocks beta 1 and beta 2 receptors
Clinical Use of Propranolol
Angina, hypertension, post-myocardial infarction, cardiomyopathy, benign tremor, migraine prophylaxis, thyrotoxicosis
Special Considerations for Propranolol
Highly lipophilic (central nervous system effects)
Adverse Effects of Propranolol
Bronchoconstriction, inhibits glycogenolysis, nightmares and mood depression
Interactions of Propranolol
Additive hypotensive effect with nitrates and antihypertensive drugs, additive bradycardia with digoxin, decreases effects of dopamine and dobutamine
Similar drugs to Propranolol
nadolol, pindolol, timolol
Pronunciation of pseudoephedrine
soo-doe-e-FED-rin
Trademark name of pseudoephedrine
Sudafed TM
Therapeutic Class of Pseudoephedrine
Decongestant
Pharmacologic Class of Pseudoephedrine
Indirect- and direct-acting adrenergic receptor agonist
M.O.A. for Pseudoephedrine
Increases release of norephineephrine and directly activates adreneggic receprots, causing vasoconstrictoin and cardiac stimulation
Clinical Use for Pseudoephedrine
Nasal decongestant for allergic and viral rhinitis
Special Considerations for Pseudoephedrine
Urine acidification or alkalinization may increase or decrease excreation, respectively
Adverse Effects
Tachycardia
Interactions of Pseudoephedrine
Concurrent use with monoamine oxidase inhibitors may cause severe hypertension.
Similar drugs to pseudoephedrine
norepinephrine, PHENYLEPHRINE
Pronunciation of Pyridostigmine
peer-i-doe-STIG-meen
Brand name of pyridostgmine
Mestinon TM
Therapeutic Class of pyridostigmine
Antimyasthenic
Pharmacologic Class of pyridostigmine
Cholinesterase inhibitor, cholinergic agonist
M.O.A. for pyridostigmine
Reversibly inhibits cholinesterase
Clinical use of pyridostigmine
Treatment of myasthenia gravis
Special Considerations for pyridostigmine
Muscarinic effects blocked by atropine
Adverse Effects of pyridostigmine
Muscarinic effects (e.g., miosis, salivation)
Interactions of pyridostigmine
Prolongs effects of succinylcholine, effects reduced by atropine, antidepressants, phenothiazine drugs, quinidine, and other drugs with anticholinergic effects.
Similiar drugs to pyridostigmine
EDROPHONIUM, neostigmine, physostigmine
What is the pronunciation of Rocuronium
roe-cue-ROE-nee-um
What is the brand name for Rocuronium
Zemuron TM
Therapeutic Class of Rocuronium
Paralytic agent
Pharmacologic Class of Rocuronium
Nondepolarizing neuromuscular blocking agent
M.O.A. for Rocurronium
Competitively blocks nicotinic receptors in skeletal muscle
Clinical Uses of Rocuronium
Skeletal muscle relaxation for intubation, surgery, and electroconvulsive therapy
Special Considerations for Rocuronium
Effects reversed by neostigmine and edrophonium
Adverse Effects of Rocuronium
Respiratory muscle paralysis and apnea
Interactions of Rocuronium
Effects potentiated by anesthetics, calcium channel blockers, tetracycline, and aminoglycoside antibiotics
Similar drugs
atracurium, mivacurium, pancuronium, tubcurarine, vecuronium
Pronunciation for Sildenafil
sil-DEN-a-fil
Brand name for sildenafil
Viagra TM
Therapeutic class for sildenafil
Vasodilator
Pharmacologic Class for sildenafil
Phosphodiesterase inhibitor
M.O.A. of Sildenafil
Inhibits type 5 phosphodiesterase and degradation of cyclic guanosine monophosphate, thereby increasng vasodilation in corpus cavernosum evoked by acetylcholine released from sacral parsympathetic neurons
Clinical Use of Sildenafil
Treatment of erectile dysfunction
Special considerations for Sildenafil
Concurrent use with organic nitrates can cause reflex tachycardia, angina, and death from myocardial ischemia
Adverse effects of Sildenafil
Headache, nasal congestion, back pain, visual disturbances
Interactions of sildenafil
Potentiates vasodilation produced by organic nitrates, serum levels increased by CYP3A4 inhibitors
Similar drugs to Sildenafil
tadalafil, vardenafil
Pronunciation of Succinylcholine
sux-sin-il-KOE-leen
Brand name for Succinylcholine
Anectine TM
Therapeutic class of Succinylcholine
Paralytic agent
Pharmacologic class of Succinylcholine
Depolarizing neuromuscular blocker
M.O.A. for Succinylcholine
Binds to nicotinic receptors, causing prolonged depolarization of skeletal muscle and paralysis.
Clinical use of Succinylcholine
Short-term skeletal muscle relazation for intubation and surgery
Special considerations for using Succinylcholine
Causes transient muscle fasciculation,effects are not reveresed by neostgmine or edrophonium.
Adverse effects of Succinylcholine
Respiratory muscle paralysis and apnea, especially in persons with rare atypical cholinesterase.
Interacations of Succinylcholine
Neuromuscular blockade enhanced by aminoglycoside antibiotics, clindamycin, amphotericin B, quinidine, and cholinesterase inhibitors.
Pronunciation of Tamsulosin
tam-soo-LOE-sin
Brand Name of Tamsulosin
Flomax TM
Therapeutic Class of Tamsulosin
Urologic agent
Pharmacologic Class of Tamsulosin
Uroselective adrenergic alpha-1 receptor antagonist
M.O.A. of Tamsulosin
Competitvely blocks alpha-1A receptors in prostrate
Clinical Use of Tamsulosin
Treatment of urinary outflow obstruction in men with prostatic hyperplasia.
Special Considerations
Not indicated for treatment of hypertension
Adverse Effects of Tamsulosin
Dizziness
Interactions of Tamsulosin
Cimetidine may increase blood levels and effects
Similar Drugs to Tamsulosin
alfuzosin, TERAZOSIN
Pronunciation of Terzosin
ter-AZ-oh-sin
Brand Name of Terazosin
Hytrin TM
Therapeutic Class of Terazosin
Antihypertensive agent
Pharmacologic Class of Terazosin
Selective adrenergic alpha-1 receptor antagonist
M.O.A. for Terazosin
Competitively blocks alpha-1 receptors
Clinical use for terazosin
Treatment of hypertension
Special Considerations for using Terazosin
Less selective for prostatic smooth muscle than tamsulosin and alfuzosin
Adverse Effects of Terazosin
Hypotension, "first-dose" syncope
Interactions of Terazosin
Additive hypotensive effect with diuretics and other antihypertensive drugs.
Similar Drugs to Terazosin
doxazosin, prazosion, TAMSULOSIN