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93 Cards in this Set

  • Front
  • Back
What is the major function of the autonomic nervous system?
controls visceral function larely outside our awareness
What do motor neurons in the central nervous system synapse with?
visceral motor neurons in autonomic ganglia which control the visceral effectors
Where is visceral motor nuclei stored in the CNS?
the hypothalamus
What are the visceral effectors involved in the ANS?
smooth muscle, glands, cardiac muscle, adipocytes
What are preganglionic neurons?
visceeral moter neurons whos cell bodies lie in the brain stem and spinal cord
What do preganglionic neurons activities represent?
direct reflex responses rather than actual responses to commands from the hypothalamus
What are autonomic ganglia?
visceral motor neurons found in the peripheral ganglia. they innervate the visceral effectors
Can a postganglionic neuron synapse with more than one preganglionic neuron?
yes
Are postganglionic neurons myelinated or unmyelinated?
unmyelinated
What are the three divisions of the ANS?
sympathetic, parasympathetic and enteric
Does the sympathetic or parasympathetic division of the ANS influence the enteric division?
both
When do the sympathetic and parasympathetic divisions work independently?
when the structure is only innervated by one division
Typically, when does the sympathetic division kick in?
periods of exertion, stress, emergency
When does the parasympathetic division dominate?
under resting conditions
Where do axons emerge from in the parasympathetic division?
the brain stem and sacral segments of the spinal cord
Where do axons emerege from in the sympathetic division?
the thoracic and superior lumbar segments of the spinal cord
What are the possible ganglionic neurons that preganglionic neurons in the spinal cord can synapse with?
-sympathetic ganglia
-collateral ganglia
-adrenal medulla
How do sympathtic chain and collateral ganglia exert their effects?
innervate peripheral target organs with postganglionic fibers
What are the target organs for sympathetic chain ganglia?
visceral effectors in the thoracic cavity, head, body wall, limbs
What are the target organs for collateral ganglia?
visceral effectors in the abdominopelvic cavity
How does the adrenal medula affect target organs throughout the body?
the release of hormones into the general circulation
Where are sympathetic chain ganglia located?
either side of the vertebral column
Where are the three collateral ganglia?
anterior to the vertebral column close to the large abdominal arteries
What are the three collateral ganglia?
-celiac
-superior mesenteric
-inferior mesenteric
Compare pre and post ganglionic fibers axons in teh sympathetic vs. parasympathetic division
the sympathetic has short preganglionic axons and long postganglionic where the parasympathetic has long preganglionic and short postganglionic
Where does the parasympathetic preganglionic fibers synapse?
terminal or intramural ganglia
Where are terminal ganglia located?
close to the target organ (synapsing on or near)
Wherer are intramural ganglia located?
within the wall of the target organ
What percentage of organs are innervated by the vagus nerve?
75%
What are the bundles that postganglionic fibers that innervate structures in the thoracic caviity called?
sympathetic nerves
What does the splanchnic bed innervate?
the digestive system and excretory organs
What is the sympathetic response of the cardiovascular system?
increased heart rate and conduction velocity, vasoconstriction in the skin and splanchnic bed, blood flow to active muscles and heart
What is the sympathetic response of the lung bronchioles?
dialation for deeper breathing
What is the sympathetic response of the skin?
pale, sweat, hairs stand up
What is the sympathetic response of the eyes?
pupil dilation; lens flattens to see further
What is the sympathetic response of the metabolism?
speeds up; release stores from the liver; mobilization of energy reserves
What is the sympathetic response of the GI tract?
decreases motility, decreases secretions
What are the purposes of the parasympathetic division?
rest and digest, housekeeping functions of the body, conservation or restoration of energy, decreased overall metabolic activity
What is the parasympathetic response of the heart?
decreased heart rate and blood pressure
What is the parasympathetic response of the GI system?
increased motility, increased secretions, increased blood flow
What is the parasympathetic response of excretory organs?
allows urination and defecation
What is the parasympathetic response of the exocrine glands?
increased production of water saliva
What is the parasympathetic response of the eye?
contraction of pupillary muscles; narrows pupil
What is dual innervation called?
autonomic tone
Where is dual innervation most evident?
GI tract, heart, and lungs
What is autonomic tone and what is it regulated by?
it is a balancing act regulated by the hypothalamus
What does "tone" indicate?
both systems are always on
What are neurouns that release acetylcholine called?
cholinergic neurons
What are neurons called that release norepinephrine?
adrenergic
What are the effects of sympathetic and parasympathetic stimulation mediated by?
membrane receptors at target organs
What type of neurons do neuross releasing norepinephrine have an effect on?
most sympathetic postganglionic neurons except sweat glands
What are the two classes of sympathetic adrenergic receptors?
alpha receptors and beta receptors
What do adrenergic receptors bind to?
norepinephrine and epinephrine
What releases norepinephrine and epinephrine to the blood?
the suprarenal medulla
What receptors are generally excited by NE/E?
a1 and b1
What receptors are generally inhibitied by NE/E?
a2 and b2
What receptor is the only receptor in adipose tisue and what do its effects cause?
b3 and it causes lipolysis
What are the two types of cholinergic receptors?
nicotinic and muscarinic
Where are nicotinic receptors located?
dendrites and cell bodies of sympathetic and parasympathetic postganglionic neurons
Where are muscarinic receptors located?
plasma membranes of all effector cells innervated by the parasympathetic postganglionic axons and most sweat glands (sympathetic)
What does exposure to ACh always cause in nicotinic receptors?
excitation of the ganglionic neuron by opening chemically gated channes in the post synaptic membrane
What is the response of muscarinic receptors to the exposure of ACh?
either activates or inactivates specific enzymes; can be excitatory or inhibitory
Is the parasympathetic or sympathetic division controlled and activated as a whole?
sympathetic
Why is the parasympathetic division called the anabolic system?
its stimulation leads to a general increase in the nutrient content of the blood
What is autonomic tone?
a continuous level of spontaneous activity of autonomic motor neurons even in the abscence of stimuli
How is it possible for both neurotransmitters to be released?
autonomic tone
Under resting conditions, which system dominates?
parasympathetic
What happens to the heart rate if there is parasympathetic inhibition or sympathetic stimulation?
heart rate increases
What is a visceral reflex?
automatic response that can be modified or facilitated by higher centers
Are visceral reflexes monosynaptic or polysynaptic?
polysynaptic
What does each visceral reflex arc consist of?
-receptor
-sensory neuron
-processing center (interneuron)
-one or two visceral motor neurons
What are the two types of visceral reflexes?
short and long
Which type of reflex predominates in the enteric nervous system?
short
What type of motor responses do short reflexes control?
simple, localized effects
How do long reflexes work?
visceral sensory neurons deliver info to teh CNS along dorsal roots of spinal nerves; interneurons process info in the CNS, ANS carries motor commands to appropriate visceral effectors
Which type of reflex is responsible forr coordinated responses involving multiple organ systems
long reflexes
What is visceral sensory info collected by?
interoceptors
Where are interoceptors primarily located?
thoracic and abdominopelvic cavities
What is the function of autonomic motor neurons?
regulates visceral activities
Where are neurons controlling parasympathetic viscerall reflexes?
sacral spinal cord s2-s4
where are neurons controlling sympathetic visceral reflexes?
spinal cord t1-l2
What is the processing center for complex visceral reflexes?
the medulla oblongata
What is the visceral sensory neurons stimulated by?
interoceptors and influence from somatic sensory and special sensory neurons
How many motor neurons do most pathways have in a series?
2 motor, 1 sensory
Where do influences from the general somatic and special senses come from?
the limbic system
What is a receptor agonist?
binds to and activates a receptor
What is an adrenergic agonist?
phenylephrine
What happens with the adrenergic agonist phenylephrine?
a1 receptors, contricts blood vesses, decreases secretions, and pupils dilate...the sympathetic nervous system is turning up
What occurs with nicotinic receptor agonists?/
stimulates receptors causing persistent depolarization; prolonged use causes desensitization/inhibition and dependence in users. BOTH SYSTEMS TURN ON
What does a muscarinic antagonist do?
blocks the neurotransmitter from exerting its effect
What do adrenergic antagonists do?
turn down the sympathetic nervous system; relaxes or decreases tension
What are beta blockers used for?
anxiety and congestive heart failure
What are alpha blockers used for?
to treat high blood pressure