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44 Cards in this Set

  • Front
  • Back

What is autonomic function?

Refers to systems that regulate and maintain the homeostasis or constant environment of the body in an unconscious fashion

What controls autonomic regulation of body homeostasis?

Humoral and Neural mechanisms - both are under CNS control

What is Humoral Control?

Endocrine responses develop slowly and have prolonged effects

What are Neural effects

Rapid reaction force- teends to act rapidly and have short term effects on viscera.

What is the Autonomic Nervous system?

PN and CN components




Responsible for rapid regulation of CV, Resp, Dogestive, Urinary, and reproductive organs

What are the subdivisions of the Visceral motor pathways?

Sympatetic, parasympathetic, and enteric



Describe the energy use of the ANS

The effects of sympathetic stim are catabolic - preparing the body to flee or fight




The effects of parasympathetic stim are anabolic - promoting normal function and conserving energy

Describe the distribution of the ANS

P: restricted to the head, neck, and body cavities




S: Distributed to all vascularized portions of the body

Describe Gladular secretion

Secretion is stimulated in all glands by parasympathetic axons except for sweat glands

How does the ANS effects Blood vessels

S: Vasocontriction (except for coronary arteries), vasomotor control,




Deep muscles - Symp produces vasodilation

What neurons are involved in ANS connections?

1st is in the CNS (preganglionic autonomic neurons. Has a thin myelinated axon and contacts neurons located in an autonomic ganglion in the body.



Autonomic Ganglion sends unmyelinated axon to visceral effector vell.

Sympathetic vs Parasympathetic Axon

S: shortpreganglionicaxon, long postgangionic


Near CNS




P: longpreganglionicaxon, short postganglionic axon


Near Effector Organ

What is included in the sympathetic ganglia?

Prevertebral and para vertebral.



What controls the Sympathetic ganglia?

Neurons located in the spinal cord which in turn are under the influence of neurons in the brain stem and hypothalamas

Describe Paravertebral Ganglia

Sympathetic chain




Theseganglia contain postganglionic neurons for innervation ofthe body wall and thoracic viscera

Describe the Prevertebral Ganglia

Associatedwith the abdominal aorta and its largerbranches). These ganglia contain postganlionicneurons that innervate abdominal viscera and partly pelvic viscera

How do the preganglionic axons travel

Neuronsin the spinal cord exit via ventralroots at spinal segments T1 through L2 andenter the sympathetic trunk via the whitecommunicating ramus

What are Splanchnic nerves

Where axons that supply the viscera pass through to connect to other prevertebral ganglia

Describe the symp innervation of the adrenal gland

Pre-gang axons from the SC innervate adrenal Medullary cells.

What are the two mechanisms that post ganglionic neurons use

Join spinal nerves via gray rami to visceral structures located in the body wall and extremities.




May form Symp Nerves to reach their targets.


-Cervical and thoracic cardiac nerves and pulmonary nerves

How do Postganglionic prevertebral symp axons travel ?

Axonsfollow the course of arteries to supply innervation to the abdominal visceraand also have control over their bloodflow

Slide 27

Describe the Parasympathetic distribution?

Preganglionicneurons are located in the brainstem nuclei of Cranial Nerves III, VII, IX andX and in sacral spinal segments S2 to S4

What innervates the viscera in the body?

Pregnaglionic parasympathetic via the vagus nerve (CNX) and neurons located in the SC from S2-S4

Slide 33

n

How is Autonomic sensory information divided?

Nociceptive (symp) and physiological (para)

Describe Nociceptors

Typicall unmyelinated small diameter axons from Dorsal root ganglia. Responds to tissue or stimuli that results from damaged tissue




Ex - overstretch, release of endogenous componds in reponse to tissue breakdown

Describe Visceral pain

Diffuse and poorly localized.


May be referred

How do non-pain visceral sensation travel?

Goes to CNS through the sacral spinal cord and to the brainstem in CN 7,9,10




Used to monitor visceral functions and homeostais

What are Chemoreceptors

areresponsive to changes in arterial oxygen and carbon dioxide, blood pH, and tosome drugs.

What are baroreceptors

areresponsive to changes in arterial blood pressure.ature

What are Osmoreceptors

areresponsive to changes in blood osmolarity

What are thermal receptors

responseto changes in blood temperature.

What is a baroreceptor reflex

basic physiological effect to control blood pressure and HR.




Glosso and Vagal afferents reportblood pressure and oxygenation to brain stem.

What are the plexuses of the gut wall?

Mynteric and submucosal


Describe the enteric plexus

Contains both motor and sensaory neurons and interneurons that are organized to produce contraction and relaxation involved in perstalsis.

Slide 44

What chemicals are used in the Symp Pre and postganglionic neuronss?

Pre - acetylcholine



Post - Norepinepherine


What chemicals are used in the Parasymp Pre and postganglionic neuronss?

Both use acetylcholine. Indicates that drugs or other agents that affect or mimic acetylcholine may have broad autonomic effects

Describe Acetylcholine receptors

Broadly classified as nicotinic and muscarinic.

Describe Nicotinic receptors

Fast and Ionotropic




Located in skeletal muscle on most Postganglionic autonomic neurons and in the CNS. Activation of CNS receptors contribute to nicotine addiction

Describe Muscarinic receptors

Slow and Gprotein mediated




Control cholinergic responses predominantly of parasympatehetic target organs - smooth muscle, cardiac.

What is the importance of location of NT receptor on target organ

Determines the response to noreepinephrine

What are the primary classes of adrenergic receptors

Alpha and beta receptors.


Different class of these wil ldetermine target organ response to both adrenergic NT and pharmacological agents.