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8 Cards in this Set

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Treatment ra
Anti- TNFalfa-monoclonal anibody:
Infliximab
Or
Anti-B cell monoclonal antibody
Rituximab

And corticosteroids
What is ms (multiple sclerosis)
AID to myelin sheath of nerve cells causing sclerosing plaques of demyelinated tissue in the white matter in the cns.
Diagnostic ms
Plaques: MRI
Symptoms ms
Motor weakness
Impaired vision
Lack of coordination
Spasticity
Pathof ms
Th1, MF, ifngamma
Patho mg
Ab block and induce endocytosis and degradation of receptors of the neuromuscular junction as ACh and calciumchannels.
Treatment mg
Pyridostigmine: Cholinesterase i: raises concentration ACh in junction, competes with ab for receptor.

Azathioprine: reduces ab production
Symptoms mg
Muscle weakness
Droopy eyelids
Double vision
Facial weakness
Chest impairng breathing