Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
117 Cards in this Set
- Front
- Back
|
Andres 2002
|
No treatment Sunrise
|
|
|
Filipeck 2002
|
Diagnostic criteria?
|
|
|
Hermelin Oconnor
|
Meaning doesnt help
|
|
|
Snowling & Frith
|
Context
|
|
|
Snowling & Frith
|
Silly word
|
|
|
Kooy96
|
Fragile x mice
|
|
|
Coomery 97
|
Social behavior not tested Brattlebro rats Low vasopressin
|
|
|
Engleman & Langraf
|
Vasopressin & Oxytocin Increase social behavior
|
|
|
Oxytocin Knockout mice
|
Genetic fx prob Silenced Social behavior deficit
|
|
|
Lijam
|
7q31 no cuddling but sensory motor probs
|
|
|
Hermelin & Oconnor 70
|
Play verbal -non-verbal -lang impared
|
|
|
Baron-Cohen 99
|
social ref 6 Asp vs. 12 controls States of eyes vs gender Amy activity in controls
|
|
|
Sigman 92
|
Feign pain Incongruous blend happy & sad Holistic
|
|
|
Infancy
|
Low lang Low symbolic play Low empathy Low joint attention Low emotion reading Low joint attention Low declarative pointing
|
|
|
Diagnosis
|
3yrs Knoblock 1900 DD 3yr 10yr Transient social probs
|
|
|
Bettelheim 67
|
Trauma Refrigerator parent Genie- L.A.
|
|
|
McAdoo + Demeyer
|
No evidence of ref
|
|
|
Gilberg 90
|
Cross cultural probs
|
|
|
Minshew 96
|
High cell density
|
|
|
Folstien & McAngelo 2000
|
Interact w env to make epigenic cluster Change manifests as more or less severe Symptoms occur
|
|
|
Cade and tidwell 2001
|
Normal lifespan
|
|
|
Stockstad 2001
|
4-20 genes
|
|
|
Andre 2002
|
7q 31 chromos
|
|
|
Fisher & Hurst
|
CAGH44 SLI
|
|
|
Betancur & Corbex 2002
|
WNT2 Mouse model No cuddling
|
|
|
Cheadle 2000
|
17-68 % TSC have A A have TSC 3%
|
|
|
Cock & Leventhal
|
Glutamergic disorder Seratonin Blood
|
|
|
Herault 96
|
Glutamergic disorder Seratonin Urine
|
|
|
Andre 2002 Inconsistent seratonin
|
Hussinger 2000
|
|
|
Morrocan families Point mutation
|
Luca 99 ADA allelle 2xfreq
|
|
|
Mundy 2003
|
P genetic drift?
|
|
|
Blatt Fitzgerald 2001
|
Hypoglutamergic disorder
|
|
|
Carlsson 98
|
Seratonin paradox
|
|
|
Stockstad 2001 prob
|
Elevated oxytocin amount Protective x chromo?
|
|
|
Petit 95
|
EN2 gene AU
|
|
|
Saiton & Corchese 98
|
MZ 65%
|
|
|
Levram 93
|
Small granule and purkinje cells Reproductive probs w guinea pig problem
|
|
|
Bachevalier 94
|
Kluver Bucy Syndrome Monkeys transient fx
|
|
|
Baron cohen 2000
|
Amy not activated by emotion
|
|
|
Bailey, Le couter and gottesman 95
|
35% genetic
|
|
|
De stefano 2001
|
Toxins
|
|
|
Pierce Corchesne 2001
|
High cerebral vloume
|
|
|
Bailey & Dean 99
|
Big basal gang HFA
|
|
|
Tager-flusber & Joseph 2001
|
Consistent with low emotional response
|
|
|
Lai 2000
|
Reeler Cytarchitectural ab
|
|
|
Bauman & Kemper 93
|
Big cell change
|
|
|
Bobnee 2000
|
Vermis
|
|
|
Ingram 2002
|
Virus infect Low play Cerebral probs
|
|
|
Stromland94
|
Thalidomide Natural tube formation
|
|
|
Monkeys
|
-viral neurochemical -other disorder
|
|
|
Mundy 2003
|
DMFC, AC =JA
|
|
|
Elgar & Campbell 2001
|
Brain Systems
|
|
|
Wananabe 99
|
Emotion
|
|
|
Kawashima 99
|
Perception of gaze
|
|
|
Critchley
|
Fundamentals imp in sociable of Kids DMFC/AC DMFC/AC/VSBS
|
|
|
Davson 2002
|
JA needed for understanding
|
|
|
Mundy and Sigman 89
|
JA deficit means autism
|
|
|
Baldwin 95
|
JA milestone of social learning
|
|
|
Sigman & Ruslin 99
|
JA for Peer relations IJA= spontaneous RJA = response
|
|
|
Mundy Kasari, Sigman & Yirmiya 90
|
IJA = no shared fx
|
|
|
Caplain 93
|
13, hemispherectomies Early Social communication scales PET Metabolic = IJA Autistic = none
|
|
|
Insel Obrien & Leckman 99
|
Oxytocin & Vasso
|
|
|
Green 2001
|
Blood oxytosin decreases
|
|
|
Joyner 91
|
EN2 4 Cerebral dev
|
|
|
Korvatska & Kamnska 2002
|
Metabolic Abnormal plasticity
|
|
|
Pierce & Corchesne 2000
|
Purkinjie and limbic Pyramidal neurons underdevel Low neuronal High packing High dendric aborization hippocampus Volume low in the hippo Cerebral hypoplasty
|
|
|
Baron Cohen
|
FMRI: face recog: Autistics temporal gyru normal fusiform
|
|
|
Wolterink 2001
|
Lesioning amy
|
|
|
Ingram 2000
|
ProbsValproic acid Little play Genetic probs Sampling error Small sample Random linkage Association analysis -ive results not encouraged MRI-small
|
|
|
Felstein and rutter 75
|
Twins 36% concordance 82% criteria large amount
|
|
|
Bolton 94
|
20% relatives large amount of pheno
|
|
|
Happe
|
Homograph
|
|
|
Hermelin & Oconnor 70
|
Memory
|
|
|
Mundy 2003
|
DMFC, AC =JA
|
|
|
Frith & Frith 2001
|
TOM, JA Gaze & RJA IJA- proto IJA-sharing
|
|
|
Mundy and Sigman 89
|
JA deficit means autism
|
|
|
Mundy 94
|
JA robust in older
|
|
|
Fox 91
|
low reward value of social stimulation
|
|
|
Baron-Cohen 95
|
TOM Modular perspective
|
|
|
Leslie 87
|
TOM Soc-neurocog mech
|
|
|
Mundy 2003
|
TOM Representation of others thoughts Interpret others behavior
|
|
|
Baron-Cohen 95
|
AU =Disrupt meta-cog model Therefore cant compare metareps Triad imparement Lang Emotion Social
|
|
|
Yirmiya 98
|
TOM deficits not spec to AU
|
|
|
Tomasello 95
|
JA fx social cog
|
|
|
Charmen 2000
|
13 TD 20m IJA IQ and lang devel control 20m IJA good 40m TOM
|
|
|
Fletcher 95
|
Tom story vs. non TD High blood to LMF gyrus
|
|
|
Goel grafman 95
|
DMFL Fx TOM tasks
|
|
|
Baron-Cohen
|
Schizophrenic autistics High DMFC activity High no of errors
|
|
|
Haznedar 2000
|
Schizos have little difficulty with TOM? High ventral brain component activity with TOM
|
|
|
Ernst 97
|
A change in DMFC disturbs dopamine activity
|
|
|
Hardan2002
|
Atypical grey in DMFC
|
|
|
Ohnishi 2000
|
PET Aut vs controls Low blood in Superior Temporal Gyri Hypermetabolism in Right AC Right AC Verbal Social Non verbal DMFC Planning Self monitoring Goal direction
|
|
|
Buch 2000
|
Exec function Low concept formation Low spontaneous inhibition Low conflict resolution Probs with monitoring a change in stragegy
|
|
|
Frith & happe 97
|
Lang tear Face
|
|
|
Ring
|
DMFC- activated Non verbal measure of central coh
|
|
|
Mundy
|
EF =Probs shifting btw soc & non social reps
|
|
|
Holroyd 2002
|
Cell groups for processing +ive and ive response DMFC
|
|
|
Schultz and Volkmar 2002
|
Fundamental disturbance in exec processes which prioritise and organize orientating to salient social stimuli
|
|
|
Stromland 94
|
No change seratonin Glutamergic Cholinergic
|
|
|
Leslie 87
|
TOM Metarep Multiple Tags
|
|
|
Mundy 2001
|
Robust
|
|
|
Kiln 2003
|
Low reward reps social stim
|
|
|
Holryd & coles 2002
|
Dopamine to ac : Rewards social activity
|
|
|
Mundy & hogan 94
|
JA-Intersubjectivity
|
|
|
Frith & Frith 2001
|
DMFC/AC relates to intersubjectivity
|
|
|
Ochsher 2002
|
AC is amplifier and filter
|
|
|
Frith 2000
|
Probs: only explains traid of impare
|
|
|
Ozonoff
|
Au have probs reading emotion
|
|
|
Baron Cohen
|
AU = eyegaze probs Paretal Low compete response Reg attention Frontal lobe damage Rigitiy and perserverence
|
|
|
Rumsey 85
|
TD vs A WCST Perserative vs dyslexics
|
|
|
Szatmari 89
|
WCST best AU Predictor
|
|
|
Jacobson 78
|
Late neurogeneration
|
|
|
Cog test
|
Rey-osterith WCST Tower hanoy
|
|
|
Ozonoff
|
96% aut low EF 87% worse second order
|
|
|
Baron cohen 89
|
Bricks
|
|
|
Muncer 88
|
2nd order 96% norm 60% MRI
|
|
|
Cohen 85
|
80% aut no pred beliefs
|
