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9 Cards in this Set
- Front
- Back
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Atropine Sulfate
Class |
Parasympathetic Blocker (Parasympatholytic or Anticholinergic)
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Atropine Sulfate
MOA |
1. Inhibits parasympathetic stimulation by blocking acetylcholine receptors
2. Decreases vagal tone resulting in increased heart rate and AV conduction 3. Dilates bronchioles and decreases respiratory tract secretions 4. Anti-secretory action suppresses sweating, lacrimation, and salivation |
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Atropine Sulfate
Indications |
1. Symptomatic bradycardia
2. Asystole 3. Pesticide poisoning 4. Pulseless Electrical Activity (PEA) less than 60 beats per minute |
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Atropine Sulfate
Contraindications |
No absolute contraindications
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Atropine Sulfate
Side Effects |
Cardiovascular: tachycardia, ventricular tachycardia/fibrillation, atrial fibrillation
Neurological: seizures, dizziness, irritability, hallucinations Respiratory: mucus plugs Other: increases intraocular pressure, worsens glaucoma, blurred vision |
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Atropine Sulfate
Precautions |
1. Administer supplemental oxygen due to the increase myocardial oxygen demand
2. May cause paradoxical slowing of the heart rate if less than the therapeutic dose is given or dose given too slowly – may also worsen Mobitz I or Mobitz II heart blocks 3. Not recommended in asymptomatic bradycardias due to the possibility of inducing or increasing a myocardial infarction |
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Atropine Sulfate
Interactions |
Tricyclic antidepressants, antihistamines, and procainamide can all potentiate the anticholinergic effects of atropine.
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Atropine Sulfate
Adult Routes / Dosages |
IVP, IO, ET, IM
Bradycardia 0.5-1.0 mg IVP/IO or 1-2 mg ET May repeat dose every 3-5 minutes to a maximum of 3 mg Asystole/PEA 1 mg IVP/IO or 2 mg ET May repeat dose every 3-5 minutes to a maximum of 3 mg Pesticides 2 mg IVP/IO/IM or 4 mg ET May repeat dose every 5 minutes until patient is asymptomatic or shows signs of atropinization |
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Atropine Sulfate
Pediatrics Routes /Dosages |
All Cardiac 0.02 mg/kg IVP/IO
Minimum single dose is 0.1 mg and maximum single dose is 0.5 mg May repeat one time in 5 minutes 0.04 mg/kg ET with no repeat Pesticides 0.05 mg/kg IVP/IO/IM or 0.1 mg/kg ET May repeat dose every 5 minutes until patient is asymptomatic or shows signs of atropinization |
