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10 Cards in this Set
- Front
- Back
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Class |
Parasympatholytic; anticholinergic; antimuscarinic; vagolytic |
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Mech |
Atropine is a competitive agonist for acetylcholine at the muscarinic receptors on the target organs of the parasympathetic system. Heart. Lungs. Salivary glands. Atropine blocks action of the parasympathetic system |
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Onset |
Immediate |
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Indications |
Symptomatic bradycardia Organophosphate/ nerve agent poisoning |
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Contra |
None |
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Precautions |
Atropine may not be effective for bradycardia associated with high level AV blocks. Consider dopamine and pacing first. Paradoxical bradycardia can occur after slow administration or small doses. Minimum 0.5mg adults. 0.1mg children. Avoid hyperthermic bradycardia |
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Side effects |
Atropine OD causes anticholinergic poisoning. Psychosis, vasodilation, dehydration, elevated temperature, pupil dilation |
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Interactions |
Additive cholinergic effects with other anitcholinergic compounds including antihistamines and TCA's |
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Dosage |
Bradycardia: 0.5 repeated every 3-5 minutes. Max dose 0.04mg/kg
Organophosphate: 1-2mg initially can be repeated every 5-60 min |
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How supplied |
1mg/10ml preloaded syringe |
