Atropine Sulfate

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ATROPINE SULFATE

CLASS: Anticholinergic
ACTION: competes reversibly with acetylcholine at the site of the muscarinic receptors
INDICATIONS: symptomatic bradycardia, asystole or PEA, organophosphate poisoning.
ADVERESE EFFECTS: dry mouth, hot skin temperature, facial flushing, blurred vision, tachycardia, ( atropine may cause paradoxical bradycardia if the dose administered is too low or if the drug too slowly).
COTRAINDICATIONS: known sensitivity, AMI, GI obstraction, closed-angle glaucoma

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DOSAGE:
SYMPTOMATIC BRADYCARDIA:
Adult: 0.5mg IV, IO every 3-5 min ( max 3mg).
Adolescent: 0.02 mg/kg (max 2mg).
Pedriatric: 0.02 mg/kg ( max 1mg).
ASYSTOLE/PULSELESS ELECTRICAL ACTIVITY:
1 mg IV, IO every 3-5 min, max dose 3 mg.
If administered via ET tube: 2 - 2.5 mg diluted in 5 to 10 ml of water or normal saline
NERNE AGENT OR ORGANOPHOSPHATE POISONING:
Adult: 2-4 mg IV, IO: may repeat if needed every 20-30 min.
Pedriatric: 0.05 mg/kg IV, IM very 10-30 min
Infants<15lb: 0.05 mg/kg every5-20 min as needed.
SPECIAL CONSIDERATION: Pregnancy class C
Half-life 2.5 hr.

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GLUCAGON

CLASS: Hormone
ACTION: Converts glycogen to glucose.
INDICATIONS: Hypoglycemia, Beta blocer overdose.
ADVERSE EFFECT: Nausea/vomiting, hypotension, sinus tachycardia.
CONTRAINDICATIONS: insulinoma, known sensitivity.

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DOSAGE:
HYPOGLYCEMIA:
Adult: 1mg IM,IV,IO, or Sub-Q
Pedriatric: (<20kg): 0.5mg, route as above.
BETA-BLOCKER OVERDOSE:
Adult: 2-5 mg IV,IO over a 1 min. period ( sec. dose of10 mg IV if the symptoms of bradycardia & hypotension recur.
Pediatric: for pt <20 kg: 0.5mg

SPECIAL CONSIDERATIONS:
Pregnancy class B