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9 Cards in this Set

  • Front
  • Back
Atropine Clsssification
-Antimuscarinic, muscarinic antagonist
-parasympathetic antagoinist
-Parasympathetic blocker
Atropine How supplied
-0.5mg/ml(prefilled syringe)
-0.4mg/ml(multidose vial)
Atropine Mechanism of Action
-Increases Heart rate(positive chronotropic effect) by accelerating SA node discharge rate and blocking vagus nerve
-Increases conduction velocity (positive dromotropic)
-little or no effect on force of contraction (inotropic effect)
-may restore cardiac rhythm in asystole or slow PEA
Atropine Mechanism of Action
Resp-relaxes bronchial smooth muscle (bronchodilation); decreases body secretions (lungs, bronchi, GI tract, sweat, saliva)
GI/GU-decreased GI motility and secretions, unrinary retention
Other-Pupil dilation, decreased sweat production
Atropine Indications
-First line drug for sympotomatic narrow QRS bradycardia
-Asystole (after epi)
-Slow PEA (after epi)
Atropine Dosing
-Symptomatic Brady--0.5mg IV push q 3-5 minutes to total dose of 3.0 mg
-Asystole/Slow PEA--1.0mg/min to 3.0mg
-ET dose 2 to 2.5 timees IV dose
Atropine Precautions
-do not push slowly or in smaller than recomended doses, small doses produce paradoxical cardiac slowing that may last 2 minutes
-may result in tachy, palpitations, and ventricular ectopy
-may worsen ischemia or induce VT/VF
-caution in acute MI, excessive increases in heart rate may further worsen ischemia or increase size of infarct
Atropine Special Considerations
-Although transplanted hearts do not usually respond to atropine because they lack vagal nerve innervation
-may be used with caution after heart transplantation, monitoring is essential
-Give O2 before giving med
-don not give unless solution is clear
Atropine Onset and Duration
-IV 1 minute (increased heart rate)
-30 minutes (decreased secretions)
-2 hours