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9 Cards in this Set
- Front
- Back
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Atropine Clsssification
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-Parasympatholytic
-Antimuscarinic, muscarinic antagonist -anticholinergic -parasympathetic antagoinist -Parasympathetic blocker |
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Atropine How supplied
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-0.5mg/ml(prefilled syringe)
-0.4mg/ml(multidose vial) |
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Atropine Mechanism of Action
(cardiovascular) |
+Cardiovascular+
-Increases Heart rate(positive chronotropic effect) by accelerating SA node discharge rate and blocking vagus nerve -Increases conduction velocity (positive dromotropic) -little or no effect on force of contraction (inotropic effect) -may restore cardiac rhythm in asystole or slow PEA |
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Atropine Mechanism of Action
(Resp/GI/GU/Other |
Resp-relaxes bronchial smooth muscle (bronchodilation); decreases body secretions (lungs, bronchi, GI tract, sweat, saliva)
GI/GU-decreased GI motility and secretions, unrinary retention Other-Pupil dilation, decreased sweat production |
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Atropine Indications
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-First line drug for sympotomatic narrow QRS bradycardia
-Asystole (after epi) -Slow PEA (after epi) |
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Atropine Dosing
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-Symptomatic Brady--0.5mg IV push q 3-5 minutes to total dose of 3.0 mg
-Asystole/Slow PEA--1.0mg/min to 3.0mg -ET dose 2 to 2.5 timees IV dose |
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Atropine Precautions
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-do not push slowly or in smaller than recomended doses, small doses produce paradoxical cardiac slowing that may last 2 minutes
-may result in tachy, palpitations, and ventricular ectopy -may worsen ischemia or induce VT/VF -caution in acute MI, excessive increases in heart rate may further worsen ischemia or increase size of infarct |
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Atropine Special Considerations
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-Although transplanted hearts do not usually respond to atropine because they lack vagal nerve innervation
-may be used with caution after heart transplantation, monitoring is essential -Give O2 before giving med -don not give unless solution is clear |
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Atropine Onset and Duration
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-IV 1 minute (increased heart rate)
-30 minutes (decreased secretions) -2 hours |
