Atropine

Front 1

Classification

Back 1

Parasympatholytic
antimusarinic
anticholinergic
parasympathetic antagonist
parasympathetic blocker

Front 2

Action

Back 2

Competes reversibly with acetylcholine at the site of the muscarinic receptors.

Receptors affected from most to least sensitive:
Salivary, Bronchial, sweat glands, eye, heart, and GI tract

Front 3

Indications

Back 3

Symptomatic bradycardia, asystole, PEA, acetylcholinesterase inhibitor poisoning (certain mushrooms, insecticides nerve gas), refractory bronchospasm

Front 4

Contraindications

Back 4

Tachycardia, hypersensitivity to atropine, obstructive disease of the GI tract, obstructive uropothy, acute narrow-angle glaucoma, acute MI, myasthenia gravis

Front 5

Adverse Effects

Back 5

Anxiety, dizziness, HA, confusion, delirium, hallucinations, coma (low doses cause sedation, high doses cause stimulation)

Anticholinergic Effects:
Delerium "Mad as a hatter"
Decreased salivation, dry mouth/nose, difficulty swallowing/speaking "Dry as a bone"
Flushed, Hot skin "Red as a Beet"
Blurred vision, photophobia "Blind as a bat"
Acute Urinary Retention
Nausea Vomiting

Front 6

Symptomatic Bradycardia Dosage

Back 6

Adult: 0.5 mg IV, IO q3-5min. NTE 3mg

Adolescent: 0.02 mg/kg IV, IO (min 0.1mg/dose; max 1mg/dose) NTE 2 mg

Pedi: 0.02 mg/kg IV, IO (min 0.1 mg/dose; max 0.5 mg/dose) NTE 1 mg

Front 7

Asystole / PEA

Back 7

1 mg IV, IO q 3-5min, max dose 3mg.

Via ET: 2 - 2.5mg diluted in 5-10 mL NS

Front 8

Nerve Agent / Organophosphate Poisoning

Back 8

2-4 mg IV, IM. Repeat as needed q 20-30 min until sx dissipate.

In severe cases, inital dose can be as large as 2-6 mg IV q 5-60 min PRN