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26 Cards in this Set
- Front
- Back
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whole blood MOA
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increases circulating blood volume
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whole blood uses
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replacement therapy for acute blood loss secondary to traumatic injuries or surgical procedures
volume expansion in clients who have extensive burn injury, dehydration, and shock |
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whole blood adverse
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circulatory overload along with common side effects of these
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PRBCS MOA
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increase the number of RBCs
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PRBCs use
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severe symptomatic anemia
hemoglobinopathies medication induced hemolytic anemia erythroblastosis fetalis |
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PRBCs adverse
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common effects
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Blood and blood products common adverse
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acute hemolytic reaction
febrile nonhemolytic reaction anaphylactic reaction mild allergic reaction hyperkalemia transfusion associated graft versus host disease sepsis |
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platelet concentrate MOA
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increases platelet counts
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platelet concentrate USe
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thrombocytopenia (platelet count less than 20000
aplastic anemia chemotherapy induced bone marrow suppression active bleeding platelet count |
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platelet adverse
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febrile nonhemolytic reaction
mild allergic reactions sepsis |
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fresh frozen plasma MOA
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replaces coagulation factors
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fresh frozen plasma use
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active bleeding or massive hemorrhage
extensive burns shock disseminated intravascular coagulation |
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fresh frozen plasma adverse
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common effects of blood and blood products
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pheresed granulocytes
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replaces neutorphils/granulocytes
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pheresed granulocytes use
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severe neutropenia (ANC less than 500)
life-theatening bacterial/fungal infection not responding to antibiotic therapy. neonatal sepsis neutrophil dysfunction |
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pheresed granulocytes adverse
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common effects of blood and blood products
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albumin MOA
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expands circulating blood volume by exerting oncotic pressure
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albumin use
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hypovolemia
hypoalbuminemia burns adult respiratory disease cardiopulmonary bypass surgery hemolytic disease of the newborn |
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albumin adverse
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risk for fluid volume excess such as pulmonary edema
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blood and blood products interventions
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acute hemolytic reaction usually occurs during the first 50 mL of infusion but onset may be delayed
if manifestations occur, stop infusion immediately keeping IV line open with 0.9 sodium chloride and new IV tubing (Iv line open for febrile nonhemolytic reaction, anaphylactic reactions, mild allergic reactions) circulatory overload: wait 2 hours between blood units if clinical manifestations occur, stop transfusion and notify provider immediately place client upright with feet down administer diuretics and oxygen as appropriate monitor I and O prior to any transfusion, assess kidney, respiratory, and cardiovascular for risk of overload sepsis- transfuse unit of blood within 2-4 hours after being removed from refrigerator obtain blood culture, send transfusion bag or analysis for possible contaminants and treat sepsis with antibiotics, IV fluids, vasopressors, steroids be aware that lysis is more likely in producs that were previously frozen or older than one week |
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blood and blood products contraindications
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hypersensitivity reactions
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whole blood, PRBCs transfusion time
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whole blood, PRBCs,- 250 mL/unit; infuse within 2-4 hours
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platelet concentrate transfusion time
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300 mL/unit infuse PRBCs within 15-30 min
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fresh frozen plasma
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200 mL/ unit infuse within 30- 60 min
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albumin
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5% 250-500 mL infuse 1 to 10 mL/min
25% 50-100 mL bottle infuse 4 mL/min |
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administration blood products
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pg. 354
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