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17 Cards in this Set

  • Front
  • Back

Diagnostic procedures for immune and infectious disorders involve:

identification of pathogenic micro-organisms.




The most accurate and definitive way to identify micro-organisms and cell characteristics is by examining blood, body fluids, and tissue samples under a microscope.

Immune and infectious disorders diagnostic procedures that nurses should be knowledgeable about:

- Serum WBC count with differential


- Radioallergosorbent test


- Skin testing for allergens

Effective treatment of infectious disease begins with:

identification of the pathogenic micro-organism

WBC, or leukocytes (5 different types)

stimulate the inflammatory response and offer protection against various types of infection and foreign antigens

the differential

Laboratory analysis of circulating WBCs




(listed so the percentages of the types of WBCs totals 100%. This number is arrived at by counting the number of each type of cell in a representative sample of 100 WBCs and multiplying it by 100. If the percentage of one type of cell increases, the percentages of other types decrease accordingly.)

Normal reference range for WBCs

5,000-10,000/mm^3




A healthy older adult can have a range of 3,000-9,000/mm^3

Leukopenia

a total WBC count of less than 4,500/mm^3




It may indicate a compromised inflammatory response or viral infection.

Leukocytosis

a total WBC count of greater than 10,000/mm^3




It may indicate an inflammatory response to a pathogen or a disease process.

Neutropenia

a neutrophil count of less than 2,000/mm^3




Neutropenia occurs in clients who are immunocompromised, are undergoing chemotherapy, or have a process that reduces the production of neutrophils.




A client who has neutropenia is at an increased risk for infection.

Neutrophils:

Percent of circulating WBCs: 55% - 75%




Increased in relation to: acute bacterial infection, fungal infection




Decreased in relation to: sepsis, radiation therapy, aplastic anemia, chemotherapy, and influenza




Additional information: the majority of neutrophils are segmented (mature) with a lesser amount being banded (not fully mature), immature neutrophils (bands) should not be found

Lymphocytes:

Percent of circulating WBCs: 20%-40%




Increased in relation to: chronic bacterial or viral infection; viruses such as mononucleosis, mumps, and measles; bacteria such as hepatitis; lymhocytic leukemia, multiple myeloma




Decreased in relation to: Leukemia, Sepsis




Additional information: T-lymphocytes initiate cell-mediated immunity, B-lymphocytes initiate humoral immunity

Monocytes:

Percent of circulating WBCs: 2%-8%




Increased in relation to: chronic inflammation; protozoal infections; tuberculosis; viral infections such as mononucleosis, mumps, and measles




Decreased in relation to: corticosteroids

Eosinophils:

Percent of circulating WBCs: 1%-4%




Increased in relation to: allergic reaction, parasitic infection, chronic inflammation, Hodgkin's disease




Decreased in relation to: stress, corticosteroids

Basophils:

Percent of circulating WBCs: 0.5%-1%




Increased in relation to: Leukemia




Decreased in relation to: acute allergic/hypersensitivity reaction, hyperthyroidism

Radioallergosorbent test (RAST)

a blood test to determine sensitivity to various allergens




It may be done in conjuction with skin testing or as an alternative when the risk of a hypersensitivity reaction to an allergen exists.

The advantage to RAST testing

it will not precipitate a dangerous allergic reaction in the client and is quicker to administer

The disadvantage to RAST testing

it is available for fewer antigens, may be less sensitive than skin testing, and is more expensive