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22 Cards in this Set

  • Front
  • Back
What layers comprise the artery?
Intima, Media and Tunica Adventitia
What cell types does the intima layer of the artery include?
endothelial and smooth muscle cells.
What is the function of the intima layer of arteries?
Very active in controlling flow and repair. (The endothelium is critical in the development of atherosclerosis)
What makes up the media layer of arteries?
Smooth muscle and collagen protein
What occurs if the media layer of the artery breaks down?
ballooning (aneurism) of the artery
What is contained in the adventitia layer of arteries?
nerves and blood vessels that contribute to the function of the artery.
What are the two types of arteries?
Muscular and Arterioles
To what type of artery does the term "resistance vessel" refer?
Muscular arteries
What is the function of muscular arteries?
1. Carry blood from the heart to the body.
2. Regulate blood flow via nerves and chemicals
3. Highly elastic
What is the function of the arterioles?
Dynamic regulation of blood flow to specific organs via dilation/constriction
Are capillaries considered arteries? (side note: this may be a leading question)
NO!!!
Capillaries of comprised mostly of what cell type?
endothelial
What is the function of capillaries? (difficulty level: you should be able to answer this in your sleep)
delivery of chemicals to tissues via a semi-permeable membrane
Permeability at the capillary depends on what?
blood flow and capillary structure
Describe the development of atherosclerosis.
1. Lipids and other chemicals irritate/inflame the endothelium
2. Arterial cells attempt to clean up with macrophages
3. This may result in the buildup of an atherosclerotic blockage and narrowing of the artery
What two processes lead up to artherosclerotic blockages?
1. accumulation of lipid
2. smooth muscle cell proliferation
What are the three types of artherosclerotic blockages?
1. fatty streak (initial lesion)
2. Advanced lesion (of the fibrous cap of the enothelium, atheroma and smooth muscle)
3. Complicated lesion
What are the 11 risk factors for artherosclerosis?
1. Smoking of tobacco
2. High blood pressure
3. Cholesterol disorders (high LDL, high triglycerides, low HDL)
4. Lack of regular physical activity
5. Diabetes Mellitus
6. Obesity
7. Male gender (lack of estrogen?)
8. Menopause (lack of estrogen.)
9. Older Age
10. Inflammatory proteins
11. Family History
What are the 4 complications of atherosclerosis?
1. Acute occlusion
2. Chronic Narrowing
3. Aneurysms
4. Embolism
What are the three types of aneurysms?
fusiform, saccular and dissecting
What is arteritis?
inflammation of arteries due to autoimmune processes
What is phlebitis?
inflammation of veins due to infection or other inflammatory processes