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29 Cards in this Set

  • Front
  • Back

Non-selective B2 Agonists

Epinephrine

Short-Acting selective B 2 Agonist

Albuterol

Long-Acting selective B2 Agonist

Salmeterol

Selective B2 Aonist (r-isomer)

Levalbuterol

Phosphodiesterase Inhibitor

Theophylline

Anticholinergic- Medium Acting

Ipratropium Bromide

Anticholinergic- Long Acting

Tiotropium Bromide

Inhaled glucocorticoid

Fluticasone

Cromones

Disodium cromoglycate

Leuktriene Receptor Blockers

Montelukast

Lipoxygenase Inhibitor

Zileuton

Anti-IgE Antibody

Omalizumab

Beta Agonist Mechanism

Relax Bronchial SM


Improve Diaphgram Contraction


Suppress mast cell release


enhance mucocilliary function


decrease microvascular permiability


inhibit phospholipase A2

Phosphodiesterase Inhibitor Mechanism

Decrease mast cell release


mucocilliary clearance


increase diaphgram contracility


relax smooth muscle

Cromone mechanism

prevent mediator release

leukotriene receptor blocker mechanism

block D,C,E receptors

inhaled glucocorticoid mechanism

slow


inhibit phospholipase A2


increase B2 receptor synthesis


decrease inflammation

Beta Agonist Side Effects

Muscle tremor, Tachy, Metabolic (K, Mg, Ca, PO4, Glucose), Psych

Anticholinergic Side Effects

Dry mouth


Bronchodilation


Decrease mucous gland secretion

Phosphodiesterase Inhibitor Side Effects

P450, similar to coffee

Cromones Side Effects

Rebound airway hypersensitivity

Inhaled glucocorticoids Side Effects

Adrenal Suppression and Candidiasis


Beta Agonist Routes

MDI, Solution, Oral, parenteral

Anticholinergic Routes

Tiotriopium Bromide- DPI Capsule, Daily


Ipratropium Bromide- MDI & Areosol

Phosphodiesterase Inhibitor Route

IV/Oral

Cromones Route

Inhalation ONLY

Inhaled glucocorticoids Route

Oral/IV/MDI, NEED spacer

Anticholinergic Indiations

Better for emphysema and bronchitis

cromones indication

prevention ONLY