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25 Cards in this Set

  • Front
  • Back
Name the Asthma/ COPD categories.
Anticholinergics
Short Acting Beta Agonist
Systemic Corticosteroids
---------------------------------------
Inhaled corticosteroids
Mast cell stabilizer
Immunomodulator
Leukotriene modifiers
Long acting beta agonist
Methylxanthines
Which class do these drugs belong to?

Ipratropium (Atrovent)
Tiotropium (Spiriva)
Anticholinergics

Block muscarinic cholinergic receptor in the bronchi causing bronchodilation
Which class do these drugs belong to?

Epinephrine
Albuterol
Levalbuterol
Short acting beta agonist

Stimulate beta-2 receptors of intracellular adenyl cylclase in smooth muscles of lungs causing bronchodilation
Which class do these drugs belong to?

Prednisone
Methylprednisone
Hydrocortisone
Systemic Corticosteroids

Suppress inflammation
Which class do these drugs belong to?

Budesonide (Pulmicort)
Flovent
Fluticasone, Triamcinolone
Inhaled Corticosteroids

Suppress inflammation
Which class do these drugs belong to?

Cromolyn (Intal)
Nedocromil (Tilade)
Mast cell stabilizers

Suppress inflammation and prevents histamine release and mast cell degranulation
Which class do these drugs belong to?

Omalizumab (Xolair)
Immunomodulators

Binds to IgE receptor on mast cells and basophils to limit release of mediators of allergic response
Which class do these drugs belong to?

Zileuton (Zyglo CR)
Zafirlukast (Accolate)
Montelukast (Singulair)
Leukotriene Modifiers

Modify inflammatory response to lipoxygenase or blocking leukotriene receptor site which will decrease bronchoconstriction, mucus production and airway edema.
Which class do these drugs belong to?

Salmterol (Serevent)
Formoterol (Foradil)
Long acting beta agonist

Stimulates adenyl cyclase to increase cAMP causing bronchodilation
Which class do these drugs belong to?

Theophylline (PO)
Aminophylline (IV)
Methylxanthines

Inhibits phosphodiesterase enzymes which prevents cAMP degradation in smooth muscle causing bronchodilation and suppression of airway stimuli
Which two meds can be used in combination to quickly treat asthma/ copd?
AA

Atrovent/ Albuterol
Which medication used to treat asthma causes an adverse reaction when given with an MAOI?
Short Acting Beta Agonists
Epinephrine, Albuterol, Levalbuterol

Long Acting Beta Agonists
Salmtereol (Serevent)
Formoterol (Foradil)

also shouldn't be given with beta blocker
Which medication used to treat asthma/ copd should be used with caution when treating diabetic patients?
Systemic corticosteroids

Prednisone, Methylprednisolone, Hydrocortisone

causes hyperglycemia
Which medication used to treat asthma/ copd leads to increased risk for tendon rupture when prescribed with a Quinolone?
Systemic corticosteroids

Prednisone, Methylprednisolone, Hydrocortisone
Which medication could lower a patients seizure threshold when attempting to treat asthma/ copd?
Systemic corticosteroids

Prednisone, Methylprednisolone, Hydrocortisone

Given with Buproprion (Wellbutrin)

dopamine uptake inhibitor for depression
This group of medications used to treat asthma/ copd long term can cause oropharyngeal candidiasis.
Inhaled Corticosteroids

Budesonide (Pulmicort)
Fluticasone, Triamcinolone (Flovent)
This long term medications used to treat asthma/ copd can cause cough and bronchospasm.
Mast Cell Stabilizers

Cromolyn (Intal)
Nedocromil (Tilade)*tastes bad
This group of long term medications used to treat asthma/ copd can all cause hepatotoxicity except?
Leukotriene Modifiers

Zileuton (Zyglo CR)
Zafirlukast (Accolate)

Montelukast (Singulair)***
does not cause hepatitis
What class of drugs used to treat long term asthma/ copd is useful in excercise induced and NSAID induced bronchospasms?
Leukotriene Modifers

Zileuton (Zyglo CR)*
Zafirlukast (Accolate)

Montelukast (Singulair)
Theophylline is given by mouth as long term treatment for asthma/ copd. What asthma/ copd class drug should it not be given with?
Leukotriene Modifiers

Only Zileuton (Zyglo CR)*
Zafirlukast (Accolate)

Note: Zyglo can not be given with Warfarin, Propanolol, or Ergots

can cause an increase [Theophylline]
Which leukotriene modifier can cause agitation, altered behavior, and hallucinations?
Montelukast (Singulair)
What is the only class of drugs used to treat long term asthma/ copd that is metabolized through the Hepatic CYP 450 System?
Leukotriene Modifiers
True or False

Short-acting beta agonists are used to treat asthma and copd?
False

just asthma
Which long acting medication used to treat asthma/ copd bronchoconstriction should not be used with azoles?
Long acting beta agonists

Salmtereol (Serevent)

causes an increased concentration of Serevent
Which medications used to treat asthma/ copd can cause arrhythmias?
Long acting beta agonists
Salmtereol (Serevent)
Formoterol (Foradil)

Methylxanthines
Theophylline (PO)
Aminophylline (IV)

note: methylxanthines are toxic and should be monitored closely. Can cause atrial fibrillation, tachycardia, and seizures