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30 Cards in this Set
- Front
- Back
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Nucleus not part of striatum |
pallidum |
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Projection neurons doesn't use GABA |
Thalamus |
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Path of D1 dopamine receptors on striatal neurons |
direct |
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Path of D2 dopamin receptors on striatal neurons |
indirect |
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Path that relays via the external segment of globus pallidus (GPe) |
indirect |
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Path that outputs via the internal segment of globus pallidus (GPi) |
both |
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Dominant mutation in Huntingtin gene |
huntington |
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drug induced choreoathetosis |
dyskinesia |
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drug stimulation of dopamine neurons in VTA or synapses accumbens |
drug addiction |
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injury of subthalamic nucleus |
hemiballismus |
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loss of nigral dopamine neurons |
Parkinson |
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loss of striatal neurons |
Huntington |
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marche a petits pas or festinating gait |
Parkinson |
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micrographia, decreasing amplitude and slowing rate when handwriting |
Parkinson |
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Motor and vocal tics |
Tourette |
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REcurrent intrusive thoughts and ritualistic behavior |
OCD |
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tremor while resting |
Parkinson |
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tremor during active movement |
essential tremor |
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chorea has graceful, dance like movements |
true |
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chorea has stereotyped repeated movements |
false |
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chorea has a premonitory urge and sense of relief on completion |
false |
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Athetosis has writhing movement of the body or face |
true |
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compulsions have a premonitory urge and sense of relief on completion |
true |
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tics are stereotyped, repeated movements and vocalizations |
true |
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tics have a premonitory urge and sense of relief on completion |
true |
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Rate limiting step in dopamine synthesis |
tyrosine hydroxylase |
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L-DOPA acts on dopamine receptors in parkinson disease |
false |
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Knowing that reserpine depletes dopamine from synaptic vesicles, this drug should improve movement in Parkinson disease |
false |
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Dopamine is inactivated by |
reuptake |
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dopamine is optically active |
false |
