Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
7 Cards in this Set
- Front
- Back
criteria for classification of RA
|
1. Morning stiffness lasting for at least 1 hr.
2. Simultaneous arthritis of 3 or more jts 4. Arthritis of hand jts 5. Symetrical Arthritis 6. Abnormal serum rhematoid factor 7. X-ray changes typical of RA on PA hand and wrist X-rays 4 of 7 must be present for at least 6 weeks |
|
Triad of Felty's syndrome
|
Seropositive Rhematoid Arthritis
Splenomegaly Granulocytopenia |
|
Limitations of NSAIDS for RA
|
often ineffective in severe cases
does not prevent damage does not alter disease course |
|
Corticosteroid
|
Limited time frame due to severe toxicity
Repeat injections ill advised in same joint w/in 3 mo. Does not alter disease course |
|
DMARD
|
may not prevent damage despite apparent clinical control
May not have lasting efficacy May not be tolerated due to toxicity Delayed onset of action |
|
proinflammatory cytokines
|
TNF alfa
IL-1 |
|
Anti-inflammatory cytokines
|
IL-1ra
sIL-1R sTNFR IL-10 IL-4 IL-11 |