Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
28 Cards in this Set
- Front
- Back
|
define mycology
|
study of fungi (yeasts/molds) that contain true nuclei, lack chlorophyll, are non-motile (except spore form) and may grow as single cells or finamentous stx
|
|
|
yeasts
|
single celled
creamy, with blastopores and pseudohyphae grow at 37 C as buds |
|
|
molds
|
.cottony, wooly, vevety, powdery or waxy
.spores and hyphae .grow at 25 C (see hyphae) |
|
|
dimorphism
|
possessing two different phases based on temp -
molds 37C, yeasts 25C |
|
|
mycelium
|
'mat' of long strands of hyphae
|
|
|
hyphae
|
-long strands of cells that intertwine to form a mycelium
-two forms 1. septate ( with wall) 2. aseptate (no wall) |
|
|
Pityriasis versicolor
|
tinea versicolor
-nondermatohpyte fungus -hyperpigmented, well demarcated -scaling lesions, -may appear hypopigments on darker skin -use KOH prep to see hyphae/buds, -use woods lamp to see yellow-green color |
|
|
pityrosporum
|
malassezia furfur or ovalis
- similar to P. versicolor |
|
|
woods lamp colors for
1. tinea capitis 2. tinea corporis 3. tinea versicolor 4. vitiligo |
1. gray or green
2. blue-green 3. yellow-green 4. willnot flouresce and will on ly reflect light |
|
|
Tinea Nigra
|
exophilia werneckii
superficial mycosi dk brown to black painless septate hyphae PALMS AND SOLES |
|
|
how do you test for T. Nigra?
|
KOH prep using scraping - to reveal septate hyphae
-SABOURAUD GLUCOSE AGAR |
|
|
Black piedra/white piedra
|
piedraia hortae
hard, black nodules on scalp hair -Trichospron beigeli - light brown, soft nodules, can affect FACIAL AND GENITAL AREAS as well as SCALP |
|
|
name 6 Tinea cutaneous mycoses
|
T. capitis
T. corporis T barbae T. cruirs T pedis T unguium |
|
|
Tinea capitis
|
scalp, no pruitis, circular alopecia
|
|
|
Tinea corporis
|
pruitic
annular central clearing borders elevated and scaly |
|
|
Tinea Cruris
|
jock itch
SPARES THE SCROTUM |
|
|
Tinea Pedis
|
athletes foot
reaction - hypersensitive allergic response see vessicles on hands |
|
|
Tinea Unguium
|
thickened, discolored brittle nails
|
|
|
sporotrichosis
|
subcutaneous fungus
gardeners, greenhouse wkers -soil, plants, wood, moss result of puncture w/ splinter incubation - 1 wk - 6mo nodule >necrotic ulcer |
|
|
sporotrichosis - what does it affect, how to tx
|
affects lymphatics
tx =oral KI if local, or Amphotericin B if disseminated |
|
|
Mycetoma - describe growth and s/s
|
slow growing, subQ lesions, affect extremities
-chara by bone deformity and oozing sinus tract |
|
|
what is known as Darlings disease?
|
Histoplasmosis
|
|
|
Histoplasmosis
cx transmission incubation dx s/s tx |
bird and BAT feces
inhalation of spores 3-21 days Ag detected in RIA urine or serum - DNA probe, sputum complement fixation, Ab 1:32 titers w/ 75%-95% + post 6 weeks s/s = pulm disx, mimics TB Tx - amphotericin B |
|
|
what mycoses can be tx with Amphotericin B?
|
histoplasmosis
Cryptococcus sporotrichosis |
|
|
Coccidioides immitus
transmission s/s labs tx |
SW US (Ca, Az)
inhaled spores 65% asympt, may see ERYTHEMA NODOSUM OR ERYTHEMA MULTIFORME, ASYMMETRICAL ARTHRITIS -lab - WBC <10k, eosiniphilia, elev ESR -grown on cotton on BAP -Ab titers >1:16 suggest extrapulmonary infx >2 fold titer = dissemination most resolve w/out tx, and have lifelong immunity |
|
|
Cryptococcus neoforms
|
ONLY pathogenic fungus to form a capsule
-see in IMC host - -presents as meningitis in HIV w/ CD4 <100 -altered mental hallmark test = India Ink , see Ag in blood or CSF CSF - eleve WBC, PRO, low glucose -Tx - amphotericin B or Diflucan |
|
|
Gilchrist's Disease
|
Blastomyces dermatidis
most asypmt, inhalation s/s - pulmonary,cutaneous (ulcerated granulomas)or systemic NO serologic skin test = Xreactivity w/ Histoplasma |
|
|
Paracoccidiodes brasiliensis
|
S. America - brazil
starts as pulmonary, becomes ulcerative lesions in mouth, nose, then lymph nodes and viscera involved |
