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18 Cards in this Set
- Front
- Back
What are the four stages of respiration?
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Glycolysis, link reaction, Krebs cycle, electron transport chain
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What happens in glycolysis? (Basic)
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Splitting of 6C glucose into two 3C pyruvate molecules
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What happens in the link reaction? (Basic)
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Conversion of 3C pyruvate into carbon dioxide and 2C molecule called acetylcoenzyme A
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What happens in the Krebs cycle? (Basic)
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The introduction of acetyl CoA into a cycle of oxidation-reduction reactions that yield some ATP and a large number of electrons
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What happens in the ETC? (Basic)
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The use of the electrons produced in the Krebs cycle to synthesise ATP with water produced as a by-product
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What are the four main stages of glycolysis?
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Activation of glucose by phosphorylation
Splitting of phosphorylated glucose (into TP) Oxidation of TP Production of ATP --> Formation of Pyruvate |
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What is the product of glycolysis?
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Net gain of two ATP molecules
Two molecules of RNAD TWO molecules of Pyruvate |
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Where are the enzymes for glycolysis found?
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In the CYTOPLASM of cells - does NOT require any organelle or membrane - no oxygen required
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Where does the link reaction/Krebs cycle take place in eukaryotic cells?
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The mitochondria
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The pyruvate molecules produced in the cytoplasm during __________ are actively transported into the ______ of the ____________
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glycolysis, matrix, mitochondria
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What happens to pyruvate in its conversion to acetyl CoA?
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It is oxidised by removing hydrogen (which is accepted by NAD)
Carbon dioxide is lost The 2C compound (acetyl group) combines with CoA to form Acetyl CoA |
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Pyruvate + NAD + CoA -->
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Acetyl CoA + RNAD + Carbon dioxide
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Where is the carbon dioxide produced in respiration?
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Directly form the molecules involved in the link reaction and Krebs cycle
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What is produced from one molecule of pyruvate in the Krebs cycle?
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Reduced coenzymes (NAD and FAD)
1 ATP molecule 3 Carbon dioxide molecules Remember this is *2 for total products |
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What does NAD do?
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It works with dehydrogenase enzymes that catalyse the removal of hydrogen ions from substrates and transfer them to other molecules such as the hydrogen carriers involved in oxidative phosphorylation
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What is the significance of the Krebs cycle? (I.e. what happens?)
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Macromolecules are broken down
Hydrogen atoms are produced that are carried by NAD to the ETC for oxidative phosphorylation It regenerates the 4C molecule that would otherwise accumulate It's a source of intermediate compounds used by cells in the manufacture of other important substances such as fatty acids, amino acids and chlorophyll |
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What's special about the mitochondria of cells that have a high metabolic rate?
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They are more densely packed with cristae
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What is the importance of oxygen in respiration?
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To act as the final acceptor of hydrogen atoms. Without its role in removing H atoms at the end of the chain, the protons would 'back up' and respiration would come to a halt. Cyanide is a non-competitive inhibitor of the final enzyme in the ETC
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